Compile Data Set for Download or QSAR
Found 26 of affinity data for UniProtKB/TrEMBL: P0C6F2
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567102(US11420959, Example I-1)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)CN)cc2)[nH]c1=O
Show InChI InChI=1S/C23H29N3O4S/c1-2-18-19(12-15-6-4-3-5-7-15)25-23(26-22(18)29)31-14-20(27)16-8-10-17(11-9-16)30-21(28)13-24/h8-11,15H,2-7,12-14,24H2,1H3,(H,25,26,29)
Affinity DataEC50:  4nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Show SMILES Cc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12
Show InChI InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)
Affinity DataEC50:  13nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567104(US11420959, Example I-3)
Show SMILES CC[C@@H](C)[C@@H](N)C(=O)Oc1ccc(cc1)C(=O)CSc1nc(CC2CCCCC2)c(CC)c(=O)[nH]1
Affinity DataEC50:  5nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567105(US11420959, Example I-4)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C3CCCN3)cc2)[nH]c1=O
Affinity DataEC50:  12nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567106(US11420959, Example I-5)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)Cc3c[nH]c4ccccc34)cc2)[nH]c1=O
Affinity DataEC50:  4nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567107(US11420959, Example I-6)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)[C@@H](C)N)cc2)[nH]c1=O
Affinity DataEC50:  4nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567108(US11420959, Example I-7)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)Cc3ccccc3)cc2)[nH]c1=O
Affinity DataEC50:  9nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567109(US11420959, Example I-8)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)CCSC)cc2)[nH]c1=O
Affinity DataEC50:  4nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567110(US11420959, Example I-9)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)CCCCN)cc2)[nH]c1=O
Affinity DataEC50:  6nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567111(US11420959, Example I-10)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)Cc3cnc[nH]3)cc2)[nH]c1=O
Affinity DataEC50:  12nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567112(US11420959, Example I-11)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)CCC(N)=O)cc2)[nH]c1=O
Affinity DataEC50:  5nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567113(US11420959, Example I-12)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)CC(N)=O)cc2)[nH]c1=O
Affinity DataEC50:  4nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567114(US11420959, Example I-13)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)C(C)C)cc2)[nH]c1=O
Affinity DataEC50:  3nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567115(US11420959, Example I-14)
Show SMILES CC[C@@H](C)[C@@H](N)C(=O)Oc1ccc(cc1)C(=O)CSc1nc(CC2CCCCC2)c(C(C)C)c(=O)[nH]1
Affinity DataEC50:  4nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567116(US11420959, Example I-15)
Show SMILES CC(C)c1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C3CCCN3)cc2)[nH]c1=O
Affinity DataEC50:  12nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567117(US11420959, Example I-16)
Show SMILES CC(C)c1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)Cc3c[nH]c4ccccc34)cc2)[nH]c1=O
Affinity DataEC50:  4nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567118(US11420959, Example I-17)
Show SMILES CC(C)c1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)CN)cc2)[nH]c1=O
Show InChI InChI=1S/C24H31N3O4S/c1-15(2)22-19(12-16-6-4-3-5-7-16)26-24(27-23(22)30)32-14-20(28)17-8-10-18(11-9-17)31-21(29)13-25/h8-11,15-16H,3-7,12-14,25H2,1-2H3,(H,26,27,30)
Affinity DataEC50:  3nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567119(US11420959, Example I-18)
Show SMILES CC(C)CC(N)C(=O)Oc1ccc(cc1)C(=O)CSc1nc(CC2CCCCC2)c(C(C)C)c(=O)[nH]1
Affinity DataEC50:  4nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567120(US11420959, Example I-19)
Show SMILES CC(C)C(N)C(=O)Oc1ccc(cc1)C(=O)CSc1nc(CC2CCCCC2)c(C(C)C)c(=O)[nH]1
Affinity DataEC50:  3nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567121(US11420959, Example I-20)
Show SMILES CSCCC(N)C(=O)Oc1ccc(cc1)C(=O)CSc1nc(CC2CCCCC2)c(C(C)C)c(=O)[nH]1
Affinity DataEC50:  3nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567122(US11420959, Example I-21)
Show SMILES CC(C)c1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)Cc3ccccc3)cc2)[nH]c1=O
Affinity DataEC50:  4nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567123(US11420959, Example I-22)
Show SMILES Cc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)Cc3ccccc3)cc2)[nH]c1=O
Affinity DataEC50:  10nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567124(US11420959, Example I-23)
Show SMILES Cc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)CN)cc2)[nH]c1=O
Show InChI InChI=1S/C22H27N3O4S/c1-14-18(11-15-5-3-2-4-6-15)24-22(25-21(14)28)30-13-19(26)16-7-9-17(10-8-16)29-20(27)12-23/h7-10,15H,2-6,11-13,23H2,1H3,(H,24,25,28)
Affinity DataEC50:  8nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567125(US11420959, Example I-24)
Show SMILES CSCCC(N)C(=O)Oc1ccc(cc1)C(=O)CSc1nc(CC2CCCCC2)c(C)c(=O)[nH]1
Affinity DataEC50:  12nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Show SMILES Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O
Show InChI InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
Affinity DataEC50:  49nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(HIV-1)
Yunnan University; Kunming Institute of Zoology, Chinese Academy of Sciences

US Patent
LigandPNGBDBM567103(US11420959, Example I-2)
Show SMILES CCc1c(CC2CCCCC2)nc(SCC(=O)c2ccc(OC(=O)C(N)CC(C)C)cc2)[nH]c1=O
Affinity DataEC50:  3nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid