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Found 36 Enz. Inhib. hit(s) with all data for entry = 50029751
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287545(4-[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287543(5-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-me...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287550(5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsul...)
Affinity DataIC50:  19nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50169640(5-(2-Ethoxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo[...)
Affinity DataIC50:  82nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50169640(5-(2-Ethoxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo[...)
Affinity DataIC50: >100nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287545(4-[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  260nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287546(5-(2-Ethoxy-phenyl)-1,3-dimethyl-1,6-dihydro-pyraz...)
Affinity DataIC50:  330nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287543(5-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-me...)
Affinity DataIC50:  390nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287550(5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsul...)
Affinity DataIC50:  460nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287551(CHEMBL52245 | N-(2-(1-methyl-7-oxo-3-propyl-6,7-di...)
Affinity DataIC50:  780nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  790nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50169640(5-(2-Ethoxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo[...)
Affinity DataIC50:  860nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287549(5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl...)
Affinity DataIC50:  960nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287544(5-(2-Hydroxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14363(3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287546(5-(2-Ethoxy-phenyl)-1,3-dimethyl-1,6-dihydro-pyraz...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287547(1-Methyl-5-(2-nitro-phenyl)-3-propyl-1,6-dihydro-p...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287548(5-Phenyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrim...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM14363(3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287545(4-[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287549(5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287550(5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsul...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287548(5-Phenyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrim...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287551(CHEMBL52245 | N-(2-(1-methyl-7-oxo-3-propyl-6,7-di...)
Affinity DataIC50:  8.30E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287546(5-(2-Ethoxy-phenyl)-1,3-dimethyl-1,6-dihydro-pyraz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14363(3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287547(1-Methyl-5-(2-nitro-phenyl)-3-propyl-1,6-dihydro-p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287543(5-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287544(5-(2-Hydroxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article