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Found 42
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123745(1-(4-methoxyphenyl)-3-(naphthalen-1-yl)-1H-pyrazol...)
Affinity DataIC50:  10nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123756(1-methyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50:  12nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123754(1-methyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50:  20nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
Affinity DataIC50:  25nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM50257541((1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50:  50nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)
Affinity DataIC50:  65nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)
Affinity DataIC50:  100nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM178081(3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (17))
Affinity DataIC50:  105nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123755(1-methyl-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-am...)
Affinity DataIC50:  120nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM178082(3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-...)
Affinity DataIC50:  120nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123745(1-(4-methoxyphenyl)-3-(naphthalen-1-yl)-1H-pyrazol...)
Affinity DataIC50:  125nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM87245(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)
Affinity DataIC50:  125nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123757(1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (...)
Affinity DataIC50:  150nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123746(1-(4-methoxyphenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50:  150nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123747(1-(tert-butyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...)
Affinity DataIC50:  250nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123746(1-(4-methoxyphenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50:  275nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123748(1-(tert-butyl)-3-methyl-1H-pyrazolo[3,4-d]pyrimidi...)
Affinity DataIC50:  350nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123751(1-(2-ethylphenyl)-3-(naphthalen-2-yl)-1H-pyrazolo[...)
Affinity DataIC50:  355nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)
Affinity DataIC50:  375nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)
Affinity DataIC50:  385nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123749(1-(2-ethylphenyl)-3-(naphthalen-1-yl)-1H-pyrazolo[...)
Affinity DataIC50:  390nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123750(1-(2-ethylphenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrim...)
Affinity DataIC50:  450nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM178083(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (19))
Affinity DataIC50:  500nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123752(3‐(naphthalen‐1‐yl)‐1̴...)
Affinity DataIC50:  545nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123747(1-(tert-butyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...)
Affinity DataIC50:  650nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123756(1-methyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50:  650nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123755(1-methyl-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-am...)
Affinity DataIC50:  695nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM3003(1,3-diphenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |...)
Affinity DataIC50:  700nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123748(1-(tert-butyl)-3-methyl-1H-pyrazolo[3,4-d]pyrimidi...)
Affinity DataIC50:  790nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123754(1-methyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50:  800nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123752(3‐(naphthalen‐1‐yl)‐1̴...)
Affinity DataIC50:  875nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123753(3-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-am...)
Affinity DataIC50:  900nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123757(1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (...)
Affinity DataIC50:  1.20E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM87231(N-[2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-...)
Affinity DataIC50:  1.23E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM3003(1,3-diphenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |...)
Affinity DataIC50:  1.25E+3nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123753(3-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-am...)
Affinity DataIC50:  1.50E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123760(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (19))
Affinity DataIC50:  1.55E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123759(3‐(naphthalen‐2‐yl)‐1HR...)
Affinity DataIC50:  1.75E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123758(3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (17))
Affinity DataIC50:  1.95E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123749(1-(2-ethylphenyl)-3-(naphthalen-1-yl)-1H-pyrazolo[...)
Affinity DataIC50:  5.20E+3nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123751(1-(2-ethylphenyl)-3-(naphthalen-2-yl)-1H-pyrazolo[...)
Affinity DataIC50:  1.55E+4nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123750(1-(2-ethylphenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrim...)
Affinity DataIC50:  3.50E+4nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed