Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 10882
TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576219BDBM576219(WO2022094012, Example 21B)
Affinity DataEC50:  0.5nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576201BDBM576201(WO2022094012, Example 6B)
Affinity DataEC50:  0.600nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576202BDBM576202(WO2022094012, Example 7)
Affinity DataEC50:  4.60nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576205BDBM576205(WO2022094012, Example 9B)
Affinity DataEC50:  6nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576216BDBM576216(WO2022094012, Example 19B)
Affinity DataEC50:  6.60nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576217BDBM576217(WO2022094012, Example 20)
Affinity DataEC50:  9.5nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576210BDBM576210(WO2022094012, Example 14)
Affinity DataEC50:  9.70nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576200BDBM576200(WO2022094012, Example 6A)
Affinity DataEC50:  12nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576203BDBM576203(WO2022094012, Example 8)
Affinity DataEC50:  14nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576213BDBM576213(WO2022094012, Example 17)
Affinity DataEC50:  19nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576208BDBM576208(WO2022094012, Example 12)
Affinity DataEC50:  20nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576218BDBM576218(WO2022094012, Example 21A)
Affinity DataEC50:  20nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576214BDBM576214(WO2022094012, Example 18)
Affinity DataEC50:  27nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576195BDBM576195(WO2022094012, Example 1B)
Affinity DataEC50:  126nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576215BDBM576215(WO2022094012, Example 19A)
Affinity DataEC50:  337nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576204BDBM576204(WO2022094012, Example 9A)
Affinity DataEC50:  416nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576209BDBM576209(WO2022094012, Example 13)
Affinity DataEC50:  634nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576207BDBM576207(WO2022094012, Example 11)
Affinity DataEC50:  778nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576196BDBM576196(WO2022094012, Example 2)
Affinity DataEC50:  813nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576206BDBM576206(WO2022094012, Example 10 | (R,E)-4-ethyl-3-methyl-...)
Affinity DataEC50:  950nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576194BDBM576194(WO2022094012, Example 1A)
Affinity DataEC50:  1.06E+3nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576211BDBM576211(WO2022094012, Example 15)
Affinity DataEC50:  1.18E+3nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576199BDBM576199(WO2022094012, Example 5)
Affinity DataEC50:  1.38E+3nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576197BDBM576197(WO2022094012, Example 3)
Affinity DataEC50:  2.50E+3nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576198BDBM576198(WO2022094012, Example 4)
Affinity DataEC50:  3.84E+3nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012

TargetOrexin receptor type 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 576212BDBM576212(WO2022094012, Example 16)
Affinity DataEC50:  3.88E+3nMAssay Description: In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022094012