Compile Data Set for Download or QSAR
Report error Found 79 Enz. Inhib. hit(s) with all data for entry = 50010929
LigandChemical structure of BindingDB Monomer ID 50100278BDBM50100278(2-(2,3-Dimethoxy-phenoxy)-4-imidazol-1-ylmethyl-be...)
Affinity DataIC50: 1nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100300BDBM50100300(2-(2,4-Dichloro-phenylsulfanyl)-4-imidazol-1-ylmet...)
Affinity DataIC50: 1nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100286BDBM50100286(4-Imidazol-1-ylmethyl-2-(naphthalen-2-yloxy)-benzo...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100279BDBM50100279(2-[3-(3-Ethyl-1-methyl-2-oxo-azepan-3-yl)-phenoxy]...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100279BDBM50100279(2-[3-(3-Ethyl-1-methyl-2-oxo-azepan-3-yl)-phenoxy]...)
Affinity DataIC50: 4.90nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in cultured v-Ha-ras-transformed RAT1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100279BDBM50100279(2-[3-(3-Ethyl-1-methyl-2-oxo-azepan-3-yl)-phenoxy]...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100305BDBM50100305(2-(2,4-Dichloro-phenoxy)-4-imidazol-1-ylmethyl-ben...)
Affinity DataIC50: 8nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100296BDBM50100296(2-(Biphenyl-3-yloxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100292BDBM50100292(2-(3-Benzoyl-phenoxy)-4-imidazol-1-ylmethyl-benzon...)
Affinity DataIC50: 13nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100303BDBM50100303(4-Imidazol-1-ylmethyl-2-(3-phenoxy-phenoxy)-benzon...)
Affinity DataIC50: 14nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100278BDBM50100278(2-(2,3-Dimethoxy-phenoxy)-4-imidazol-1-ylmethyl-be...)
Affinity DataIC50: 14nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in cultured v-Ha-ras-transformed RAT1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100308BDBM50100308(4-Imidazol-1-ylmethyl-2-(3-phenylamino-phenoxy)-be...)
Affinity DataIC50: 17nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100300BDBM50100300(2-(2,4-Dichloro-phenylsulfanyl)-4-imidazol-1-ylmet...)
Affinity DataIC50: 23nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100309BDBM50100309(2-(3-tert-Butyl-phenoxy)-4-imidazol-1-ylmethyl-ben...)
Affinity DataIC50: 27nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100283BDBM50100283(2-(3-Ethynyl-phenoxy)-4-imidazol-1-ylmethyl-benzon...)
Affinity DataIC50: 27nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100311BDBM50100311(2-(3,4-Dichloro-phenoxy)-4-imidazol-1-ylmethyl-ben...)
Affinity DataIC50: 28nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100299BDBM50100299(N-[3-(2-Cyano-5-imidazol-1-ylmethyl-phenoxy)-pheny...)
Affinity DataIC50: 38nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100298BDBM50100298(2-(3-Bromo-phenoxy)-4-imidazol-1-ylmethyl-benzonit...)
Affinity DataIC50: 38nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100290BDBM50100290(3-(2-Cyano-5-imidazol-1-ylmethyl-phenoxy)-N-phenyl...)
Affinity DataIC50: 38nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100304BDBM50100304(2-(4-Chloro-phenoxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50: 38nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100289BDBM50100289(4-Imidazol-1-ylmethyl-2-(3-methoxy-phenoxy)-benzon...)
Affinity DataIC50: 40nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100294BDBM50100294(2-(2-Chloro-phenoxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50: 41nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100287BDBM50100287(2-(3-Acetyl-phenoxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50: 45nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100302BDBM50100302(2-(3-Chloro-phenoxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50: 53nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100307BDBM50100307(2-(2-Biphenyl-4-yl-ethoxy)-4-imidazol-1-ylmethyl-b...)
Affinity DataIC50: 86nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100300BDBM50100300(2-(2,4-Dichloro-phenylsulfanyl)-4-imidazol-1-ylmet...)
Affinity DataIC50: 96nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in cultured v-Ha-ras-transformed RAT1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100276BDBM50100276(2-(2,5-Dimethoxy-phenoxy)-4-imidazol-1-ylmethyl-be...)
Affinity DataIC50: 100nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100293BDBM50100293(2-(Biphenyl-2-yloxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50: 110nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100291BDBM50100291(2-(3-Cyano-phenoxy)-4-imidazol-1-ylmethyl-benzonit...)
Affinity DataIC50: 130nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100310BDBM50100310(4-Imidazol-1-ylmethyl-2-(naphthalen-1-yloxy)-benzo...)
Affinity DataIC50: 150nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100306BDBM50100306(2-(3-Fluoro-phenoxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50: 180nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100282BDBM50100282(4-Imidazol-1-ylmethyl-2-(3-phenyl-propoxy)-benzoni...)
Affinity DataIC50: 200nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100281BDBM50100281(4-Imidazol-1-ylmethyl-2-phenoxy-benzonitrile | CHE...)
Affinity DataIC50: 230nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100277BDBM50100277(2-(3-Benzyl-phenoxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50: 230nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100305BDBM50100305(2-(2,4-Dichloro-phenoxy)-4-imidazol-1-ylmethyl-ben...)
Affinity DataIC50: 260nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in cultured v-Ha-ras-transformed RAT1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100303BDBM50100303(4-Imidazol-1-ylmethyl-2-(3-phenoxy-phenoxy)-benzon...)
Affinity DataIC50: 280nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100305BDBM50100305(2-(2,4-Dichloro-phenoxy)-4-imidazol-1-ylmethyl-ben...)
Affinity DataIC50: 280nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100295BDBM50100295(4-Imidazol-1-ylmethyl-2-(4-methoxy-phenoxy)-benzon...)
Affinity DataIC50: 290nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100312BDBM50100312(4-Imidazol-1-ylmethyl-2-(2-methoxy-phenoxy)-benzon...)
Affinity DataIC50: 340nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100297BDBM50100297(4-Imidazol-1-ylmethyl-2-(4-phenyl-butoxy)-benzonit...)
Affinity DataIC50: 380nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100313BDBM50100313(2-(2,4-Dichloro-benzenesulfinyl)-4-imidazol-1-ylme...)
Affinity DataIC50: 390nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100297BDBM50100297(4-Imidazol-1-ylmethyl-2-(4-phenyl-butoxy)-benzonit...)
Affinity DataIC50: 440nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100285BDBM50100285(4-{5-[4-(3-Chloro-phenyl)-2-(2-methanesulfonyl-eth...)
Affinity DataIC50: 475nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100296BDBM50100296(2-(Biphenyl-3-yloxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50: 520nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100309BDBM50100309(2-(3-tert-Butyl-phenoxy)-4-imidazol-1-ylmethyl-ben...)
Affinity DataIC50: 520nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100286BDBM50100286(4-Imidazol-1-ylmethyl-2-(naphthalen-2-yloxy)-benzo...)
Affinity DataIC50: 520nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100277BDBM50100277(2-(3-Benzyl-phenoxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50: 600nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100308BDBM50100308(4-Imidazol-1-ylmethyl-2-(3-phenylamino-phenoxy)-be...)
Affinity DataIC50: 630nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100293BDBM50100293(2-(Biphenyl-2-yloxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50: 740nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100292BDBM50100292(2-(3-Benzoyl-phenoxy)-4-imidazol-1-ylmethyl-benzon...)
Affinity DataIC50: 840nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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