Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 3107
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28104(3-cyanoquinoline, 29 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28091(3-cyanoquinoline, 16 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28105(3-cyanoquinoline, 30 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28112(3-cyanoquinoline, 37 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  13nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28110(3-cyanoquinoline, 35 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  14nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28106(3-cyanoquinoline, 31 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28111(3-cyanoquinoline, 36 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  15nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28115(3-cyanoquinoline, 40 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  16nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28114(3-cyanoquinoline, 39 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  16nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28109(3-cyanoquinoline, 34 | {2-[4-(3-{[4-({3-chloro-4-[...)
Affinity DataIC50:  17nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28107(3-cyanoquinoline, 32 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28095(3-cyanoquinoline, 20 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28098(3-cyanoquinoline, 23 | 7-{3-[tert-butyl(2-hydroxye...)
Affinity DataIC50:  24nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28096(3-cyanoquinoline, 21 | 7-({3-[bis(2-hydroxyethyl)a...)
Affinity DataIC50:  26nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28088(3-cyanoquinoline, 13 | 4-({3-chloro-4-[(1,4,5-trim...)
Affinity DataIC50:  26nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28099(3-cyanoquinoline, 24 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28092(3-cyanoquinoline, 17 | 4-({3-bromo-4-[(1,4,5-trime...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28103(3-cyanoquinoline, 28 | N-(3-{[4-({3-chloro-4-[(1-e...)
Affinity DataIC50:  31nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28101(3-cyanoquinoline, 26 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  32nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28100(3-cyanoquinoline, 25 | 4-(3-{[4-({3-chloro-4-[(1-e...)
Affinity DataIC50:  45nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28113(3-cyanoquinoline, 38 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  47nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28118(3-cyanoquinoline, 3 | 4-({3-chloro-4-[(1-methyl-1H...)
Affinity DataIC50:  50nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28089(3-cyanoquinoline, 14 | 4-({4-[(1-benzyl-4,5-dimeth...)
Affinity DataIC50:  65nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28123(3-cyanoquinoline, 8 | 4-({3-chloro-4-[(1-methyl-1H...)
Affinity DataIC50:  66nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28108(3-cyanoquinoline, 33 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  67nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28117(3-cyanoquinoline, 42 | 4-[(3-chloro-4-{[4,5-dimeth...)
Affinity DataIC50:  79nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28119(3-cyanoquinoline, 4 | 4-({3-chloro-4-[(1-methyl-1H...)
Affinity DataIC50:  88nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28102(3-cyanoquinoline, 27 | ethyl 1-(3-{[4-({3-chloro-4...)
Affinity DataIC50:  135nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28087(3-cyanoquinoline, 2 | 4-({3-chloro-4-[(1-methyl-1H...)
Affinity DataIC50:  140nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28121(3-cyanoquinoline, 6 | 4-({3-chloro-4-[(1-methyl-1H...)
Affinity DataIC50:  150nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28120(3-cyanoquinoline, 5 | 4-({3-chloro-4-[(1-methyl-1H...)
Affinity DataIC50:  151nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28116(3-cyanoquinoline, 41 | 4-({3-chloro-4-[(4,5-dimeth...)
Affinity DataIC50:  189nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28090(3-cyanoquinoline, 15 | 4-({3-chloro-4-[(1,5-dimeth...)
Affinity DataIC50:  291nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28093(3-cyanoquinoline, 18 | 7-{[3-(dimethylamino)propyl...)
Affinity DataIC50:  394nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28127(3-cyanoquinoline, 12 | 4-({3-chloro-4-[(1-methyl-1...)
Affinity DataIC50:  600nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28126(3-cyanoquinoline, 11 | 4-({3-chloro-4-[(1-methyl-1...)
Affinity DataIC50:  847nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28122(3-cyanoquinoline, 7 | 6-methoxy-4-({4-[(1-methyl-1...)
Affinity DataIC50:  1.00E+3nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28124(3-cyanoquinoline, 9 | 6-methoxy-7-[3-(morpholin-4-...)
Affinity DataIC50:  1.09E+3nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28097(3-cyanoquinoline, 22 | N-(3-{[4-({3-chloro-4-[(1-e...)
Affinity DataIC50:  3.88E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28125(3-cyanoquinoline, 10 | 4-{[3-chloro-4-(pyridin-2-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28094(3-cyanoquinoline, 19 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  1.37E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed