Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50015199
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152951((S)-4-[4-(2,5-Difluoro-benzyl)-piperidin-1-yl]-2,3...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152951((S)-4-[4-(2,5-Difluoro-benzyl)-piperidin-1-yl]-2,3...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152940((S)-7-[4-(2,5-Difluoro-benzyl)-piperidin-1-yl]-2,3...)
Affinity DataIC50: 5.5nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152942((S)-4-[4-(2-Iodo-benzyl)-piperazin-1-yl]-2,3,4,6-t...)
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152955(4-[4-(2-bromobenzyl)hexahydro-1-pyridinyl]spiro[cy...)
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152946(4-[4-(2-iodobenzyl)hexahydro-1-pyrazinyl]spiro[cyc...)
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152948(4-[4-(2-iodobenzyl)hexahydro-1-pyrazinyl]spiro[cyc...)
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152959(4-[4-(2-methoxybenzyl)hexahydro-1-pyridinyl]spiro[...)
Affinity DataIC50: 59nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152939(4-[4-(2-bromobenzyl)hexahydro-1-pyridinyl]spiro[cy...)
Affinity DataIC50: 73nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152960(4-[4-(2-bromo-5-fluorobenzyl)hexahydro-1-pyridinyl...)
Affinity DataIC50: 77nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152947(4-[4-(2-bromo-5-fluorobenzyl)hexahydro-1-pyridinyl...)
Affinity DataIC50: 82nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152958(4-[4-(2-bromo-5-methoxybenzyl)hexahydro-1-pyraziny...)
Affinity DataIC50: 91nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152953(4-[4-(2,5-dichlorobenzyl)hexahydro-1-pyrazinyl]spi...)
Affinity DataIC50: 92nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152952(4-[4-(2-chlorobenzyl)hexahydro-1-pyridinyl]spiro[c...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152956(4-[4-(2,5-difluorobenzyl)hexahydro-1-pyridinyl]spi...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152945(4-[4-(2-chlorobenzyl)hexahydro-1-pyridinyl]spiro[c...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152950(4-[4-(2-methoxybenzyl)hexahydro-1-pyridinyl]spiro[...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152941(4-[4-(2-trifluorobenzyl)hexahydro-1-pyridinyl]spir...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152949(4-[4-(2,5-difluorobenzyl)hexahydro-1-pyrazinyl]spi...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152954(4-[4-(2-fluoro-5-methoxybenzyl)hexahydro-1-pyrazin...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152944(4-[4-(2-fluorobenzyl)hexahydro-1-pyridinyl]spiro[c...)
Affinity DataIC50: 410nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152938(4-[4-(2-fluoro-5-methoxybenzyl)hexahydro-1-pyrazin...)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152943(4-[4-(2-fluorobenzyl)hexahydro-1-pyridinyl]spiro[c...)
Affinity DataIC50: 480nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152957(4-[4-(2-trifluorobenzyl)hexahydro-1-pyridinyl]spir...)
Affinity DataIC50: 510nMAssay Description:Inhibitory activity against human- serotonin reuptake transmitter using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed