Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 3159
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM28802(2-{[(5-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataIC50: 97nM EC50:  4nMpH: 8.0 T: 2°CAssay Description:For hPPAR alpha, percentage inhibition was calculated relative to unlabeled GW2331, which was used as the active site-specific competitive binder. Fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM28800(2-{[(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataIC50: 260nM EC50:  10nMpH: 8.0 T: 2°CAssay Description:For hPPAR alpha, percentage inhibition was calculated relative to unlabeled GW2331, which was used as the active site-specific competitive binder. Fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
LigandPNGBDBM28802(2-{[(5-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50:  123nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Bristol-Myers Squibb

LigandPNGBDBM28802(2-{[(5-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50:  145nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Golden hamster)
Bristol-Myers Squibb

LigandPNGBDBM28802(2-{[(5-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50:  178nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
LigandPNGBDBM28800(2-{[(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50:  317nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Bristol-Myers Squibb

LigandPNGBDBM28800(2-{[(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50:  426nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Golden hamster)
Bristol-Myers Squibb

LigandPNGBDBM28800(2-{[(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50:  488nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb

LigandPNGBDBM28800(2-{[(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataIC50: 1.50E+4nM EC50:  4.10E+3nMpH: 8.0 T: 2°CAssay Description:For PPARgamma, the percentage inhibition was calculated relative to rosiglitazone, which was used as the active site-specific competitive binder. Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb

LigandPNGBDBM28802(2-{[(5-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataIC50: 1.50E+4nM EC50:  4.51E+3nMpH: 8.0 T: 2°CAssay Description:For PPARgamma, the percentage inhibition was calculated relative to rosiglitazone, which was used as the active site-specific competitive binder. Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM28803(Clofop | HCG 004 | 2-[4-(4-chlorophenoxy)phenoxy]p...)
Affinity DataIC50: 9.84E+4nM EC50:  1.16E+4nMpH: 8.0 T: 2°CAssay Description:For hPPAR alpha, percentage inhibition was calculated relative to unlabeled GW2331, which was used as the active site-specific competitive binder. Fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
LigandPNGBDBM28803(Clofop | HCG 004 | 2-[4-(4-chlorophenoxy)phenoxy]p...)
Affinity DataEC50:  1.77E+4nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Bristol-Myers Squibb

LigandPNGBDBM28803(Clofop | HCG 004 | 2-[4-(4-chlorophenoxy)phenoxy]p...)
Affinity DataEC50:  1.85E+4nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Bristol-Myers Squibb

LigandPNGBDBM28800(2-{[(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50: >2.50E+4nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Bristol-Myers Squibb

LigandPNGBDBM28802(2-{[(5-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50: >2.50E+4nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Golden hamster)
Bristol-Myers Squibb

LigandPNGBDBM28803(Clofop | HCG 004 | 2-[4-(4-chlorophenoxy)phenoxy]p...)
Affinity DataEC50:  2.87E+4nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb

LigandPNGBDBM28803(Clofop | HCG 004 | 2-[4-(4-chlorophenoxy)phenoxy]p...)
Affinity DataIC50: 9.84E+4nM EC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:For PPARgamma, the percentage inhibition was calculated relative to rosiglitazone, which was used as the active site-specific competitive binder. Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2009
Entry Details Article
PubMed