Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50039014
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303940BDBM50303940(2-(Benzylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,6-...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303950BDBM50303950(Isosorbide-2-benzylcarbamate-5-(o-toluate) | CHEMB...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253231BDBM50253231(Isosorbide-2-(benzylcarbamate)-5-benzoate | (3R,3a...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303952BDBM50303952(2-(Dimethylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303951BDBM50303951(2-(Ethylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,6-d...)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253266BDBM50253266((3R,3aR,6S,6aR)-6-(benzylcarbamoyloxy)hexahydrofur...)
Affinity DataIC50: 12nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303941BDBM50303941(2-(Benzylaminocarbonyloxy-)5-O-(m-hydroxybenzoyl)-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303943BDBM50303943(2-(Benzylaminocarbonyloxy-)5-O-(o-nitro-benzoyl)-1...)
Affinity DataIC50: 18nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004000BDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 19nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303946BDBM50303946(2-(benzylaminocarbonyloxy-)5-O-(o-amino-benzoyl)-1...)
Affinity DataIC50: 27nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303944BDBM50303944(2-(Benzylaminocarbonyloxy-)5-O-(m-nitro-benzoyl)-1...)
Affinity DataIC50: 32nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10620BDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 37nMAssay Description:Inhibition of BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303949BDBM50303949(2-(Benzylaminocarbonyloxy-)5-O-(o-nitroso-benzoyl)...)
Affinity DataIC50: 39nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004000BDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 53nMAssay Description:Inhibition of electric eel AChE type 6SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253230BDBM50253230((3R,3aR,6S,6aR)-6-(benzylcarbamoyloxy)hexahydrofur...)
Affinity DataIC50: 57nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303939BDBM50303939((3R,3aR,6S,6aR)-6-(butylcarbamoyloxy)hexahydrofuro...)
Affinity DataIC50: 72nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303947BDBM50303947(2-(Benzylaminocarbonyloxy-)5-O-(m-amino-benzoyl)-1...)
Affinity DataIC50: 86nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303945BDBM50303945(2-(Benzylaminocarbonyloxy-)5-O-(p-nitro-benzoyl)-1...)
Affinity DataIC50: 117nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303948BDBM50303948(2-(Benzylaminocarbonyloxy-)5-O-(p-amino-benzoyl)-1...)
Affinity DataIC50: 297nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303942BDBM50303942(2-(Benzylaminocarbonyloxy-)5-O-(p-hydroxy-benzoyl)...)
Affinity DataIC50: 323nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303954BDBM50303954(2-(Morpholinocarbonyloxy-)5-O-salicyloyl-1,4:3,6-d...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303953BDBM50303953(2-(Diethylaminocarbonyloxy-)5-O-salicyloyl-1,4:3,6...)
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303940BDBM50303940(2-(Benzylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,6-...)
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of human CES2-mediated pNPA substrate turnoverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Trinity College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252790BDBM50252790(isosorbide-2-benzyl carbamate | Isosorbide-2-benzy...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed