Compile Data Set for Download or QSAR
maximum 50k data
Found 91 Enz. Inhib. hit(s) with all data for entry = 50033096
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50229787((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...)
Affinity DataIC50:  61nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339398((+)-R-3-(4-Chlorophenyl)-3-(1-hydroxymethylcyclopr...)
Affinity DataIC50:  170nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339369((+/-)-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cycl...)
Affinity DataIC50:  230nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339371((+/-)-trans-3-(4-Chlorophenyl)-3-(4-hydroxycyclohe...)
Affinity DataIC50:  310nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339355((+/-)-3-(4-Chlorophenyl)-3-(4-hydroxybutoxy)-2-(4-...)
Affinity DataIC50:  360nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339365((+/-)-trans-3-(4-Chlorophenyl)-3-(5-hydroxycyclooc...)
Affinity DataIC50:  380nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339370((+/-)-trans-3-(4-Chlorophenyl)-3-(4-hydroxycyclohe...)
Affinity DataIC50:  390nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339368((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxy-2,2-dimethyl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339437((+/-)-3-(4-chlorophenyl)-3-((cis)-3-hydroxycyclope...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339353((+/-)-(Z)-3-(4-Chlorophenyl)-3-(4-hydroxybut-2-eny...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339354((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxypropoxy)-2-(4...)
Affinity DataIC50:  450nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339361((+/-)-3-(4-Bromophenyl)-3-(4-hydroxybutoxy)-2-(4-n...)
Affinity DataIC50:  570nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339367((+/-)-cis-3-(4-Chlorophenyl)-3-(2-hydroxymethylcyc...)
Affinity DataIC50:  570nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339363((+/-)-trans-3-(4-Chlorophenyl)-3-(4-hydroxymethylc...)
Affinity DataIC50:  580nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339366((+/-)-3-(4-Chlorophenyl)-3-(4-hydroxybut-2-ynyloxy...)
Affinity DataIC50:  660nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339436((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxycyclopentoxy)...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339364((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxymethylbenzylo...)
Affinity DataIC50:  730nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339357((+/-)-(S)-3-(4-Chlorophenyl)-2-[1-(4-chlorophenyl)...)
Affinity DataIC50:  900nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339362((+/-)-3-(4-Chlorophenyl)-3-(4-hydroxymethylbenzylo...)
Affinity DataIC50:  980nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339375((+/-)-2-(4-Bromobenzyl)-3-(4-chlorophenyl)-3-((1-(...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339399((-)-S-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cycl...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339360((+/-)-3-(4-Bromophenyl)-3-(3-hydroxypropoxy)-2-(4-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339351((+/-)-cis-3-(4-Chlorophenyl)-3-(4-hydroxycyclopent...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339376((+/-)-3-(4-Chlorophenyl)-3-(1-hydroxymethylcyclopr...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339440((+/-)-cis-3-(4-Chlorophenyl)-3-(4-hydroxycyclopent...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339372((+/-)-4-((1-(4-Chlorophenyl)-1-((1-(hydroxymethyl)...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339352((+/-)-cis-3-(4-Chlorophenyl)-3-(4-hydroxycyclopent...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339438((+/-)-cis-4-((1-(4-Chlorophenyl)-1-(4-hydroxycyclo...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339377((+/-)-3-(4-Chlorophenyl)-3-(1-hydroxy-2-cyclopropy...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339374((+/-)-2-(4-Chlorobenzyl)-3-(4-chlorophenyl)-3-((1-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339408(3-(4-chlorophenyl)-3-hydroxy-2-(4-nitrobenzyl)isoi...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339358((+/-)-(R)-3-(4-Chlorophenyl)-2-[1-(4-chlorophenyl)...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339373((+/-)-3-(4-Chlorophenyl)-2-(4-fluorobenzyl)-3-(1-h...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339378((+/-)-3-(4-Chlorophenyl)-3-(1-hydroxymethylcyclopr...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339435((+/-)-(cis/trans)-2-Benzyl-3-(4-chlorophenyl)-3-(3...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339407(3-(4-Bromophenyl)-3-hydroxy-2-(4-nitrobenzyl)isoin...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339359((+/-)-3-(4-Chlorophenyl)-3-(4-hydroxybutoxy)-2-[2-...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339356((+/-)-4-[1-(4-Chlorophenyl)-1-(4-hydroxybutoxy)-3-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339415(3-(4-Chlorophenyl)-3-hydroxy-2-(4-chlorobenzyl)iso...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339414(2-(4-bromobenzyl)-3-(4-chlorophenyl)-3-hydroxyisoi...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339439((+/-)-cis-2-Benzyl-3-(4-chlorophenyl)-3-(4-hydroxy...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339411(2-(4-(Aminomethyl)benzonitrile)-3-(4-chlorophenyl)...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339404(3-(4-Chlorophenyl)-3-hydroxy-2-[2-(4-nitrophenyl)e...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339403(2-(4-aminophenethyl)-3-(4-chlorophenyl)-3-hydroxyi...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339405(3-(4-chlorophenyl)-3-hydroxy-2-phenethylisoindolin...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339379((+/-)-3-(4-Chlorophenyl)-2-((R)-1-(4-chlorophenyl)...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339380((+/-)-3-(4-Chlorophenyl)-2-((S)-1-(4-chlorophenyl)...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339409(3-(4-Fluorophenyl)-3-hydroxy-2-(4-nitrobenzyl)-2,3...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339392((+/-)-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cycl...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339424(CHEMBL1688159 | Methyl 4-((1-(4-chlorophenyl)-1-hy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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