Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50040192
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390701(CHEMBL2070229)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390710(CHEMBL2070319)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390703(CHEMBL2070231)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390702(CHEMBL2070230)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390709(CHEMBL2070318)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390713(CHEMBL2070228)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390708(CHEMBL2070317)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390705(CHEMBL2070314)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390707(CHEMBL2070316 | US8486964, 1)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390699(CHEMBL2070226)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390712(CHEMBL2070321)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390706(CHEMBL2070315 | US8486964, 4)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390700(CHEMBL2070227)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390693(CHEMBL2070218)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390698(CHEMBL2070225)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390700(CHEMBL2070227)
Affinity DataIC50: 362nMAssay Description:Inhibition of 11beta-HSD1 in mouse 3T3L1 cells assessed as conversion of cortisone to cortisol level after 150 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390700(CHEMBL2070227)
Affinity DataIC50: 362nMAssay Description:Inhibition of 11beta-HSD1 in mouse 3T3L1 cells assessed as conversion of cortisone to cortisol level after 150 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390704(CHEMBL2070313)
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390697(CHEMBL2070224)
Affinity DataIC50: 430nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390711(CHEMBL2070320)
Affinity DataIC50: 439nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390696(CHEMBL2070223)
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390692(CHEMBL2070215)
Affinity DataIC50: 780nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390695(CHEMBL2070222)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390702(CHEMBL2070230)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of 11beta-HSD1 in mouse 3T3L1 cells assessed as conversion of cortisone to cortisol level after 150 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390702(CHEMBL2070230)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of 11beta-HSD1 in mouse 3T3L1 cells assessed as conversion of cortisone to cortisol level after 150 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390694(CHEMBL2070220)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390700(CHEMBL2070227)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390702(CHEMBL2070230)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed