Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50046640
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122844(CHEMBL3622175)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human ERG by by patchXpress methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122844(CHEMBL3622175)
Affinity DataIC50: >3.00E+4nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122844(CHEMBL3622175)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122831(CHEMBL3622177)
Affinity DataEC50:  7.10nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122838(CHEMBL3622176)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122838(CHEMBL3622176)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122844(CHEMBL3622175)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122846(CHEMBL3622174)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122849(CHEMBL3622173)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122850(CHEMBL3622172)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122870(CHEMBL3622171)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122875(CHEMBL3622170)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122909(CHEMBL3622169)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122931(CHEMBL3622168)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122932(CHEMBL3622167)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122933(CHEMBL3622166)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122934(CHEMBL3622165)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122935(CHEMBL3622164)
Affinity DataEC50:  8.70nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122755(CHEMBL3622180)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122756(CHEMBL3622179)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122794(CHEMBL3622178)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122838(CHEMBL3622176)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122838(CHEMBL3622176)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122844(CHEMBL3622175)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122846(CHEMBL3622174)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122849(CHEMBL3622173)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122850(CHEMBL3622172)
Affinity DataEC50:  5.20nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122870(CHEMBL3622171)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122875(CHEMBL3622170)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122909(CHEMBL3622169)
Affinity DataEC50:  15nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122931(CHEMBL3622168)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122932(CHEMBL3622167)
Affinity DataEC50:  9.90nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122933(CHEMBL3622166)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122934(CHEMBL3622165)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122935(CHEMBL3622164)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122936(CHEMBL3622181)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122947(CHEMBL3622182)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122794(CHEMBL3622178)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122831(CHEMBL3622177)
Affinity DataEC50:  13nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122755(CHEMBL3622180)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122756(CHEMBL3622179)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed