Compile Data Set for Download or QSAR
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Found 13 Enz. Inhib. hit(s) with all data for entry = 50020664
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216173(CHEMBL230245 | N-[(1S,2R)-2-amino-1-benzyl-3-fluor...)
Affinity DataIC50:  2nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216175(CHEMBL425828 | N-[(1S,2R)-2-amino-1-benzyl-3-metho...)
Affinity DataIC50:  12nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216179(CHEMBL395084 | N-[(1S)-1-benzyl-2-hydroxyethyl]-2-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216174(CHEMBL230355 | N-[(1S,2R)-2-amino-1-benzyl-3-fluor...)
Affinity DataIC50:  18nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216176(CHEMBL230250 | N-[(1S)-2-amino-1-benzylethyl]-2-{t...)
Affinity DataIC50:  34nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216173(CHEMBL230245 | N-[(1S,2R)-2-amino-1-benzyl-3-fluor...)
Affinity DataIC50:  49nMAssay Description:Inhibition of BACE1 assessed as effect on soluble APPbeta N-terminal fragment secretion in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216175(CHEMBL425828 | N-[(1S,2R)-2-amino-1-benzyl-3-metho...)
Affinity DataIC50:  173nMAssay Description:Inhibition of BACE1 assessed as effect on soluble APPbeta N-terminal fragment secretion in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216176(CHEMBL230250 | N-[(1S)-2-amino-1-benzylethyl]-2-{t...)
Affinity DataIC50:  280nMAssay Description:Inhibition of BACE1 assessed as effect on soluble APPbeta N-terminal fragment secretion in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216178(CHEMBL394850 | N-[(1S)-1-benzyl-2-hydroxyethyl]-2-...)
Affinity DataIC50:  350nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216174(CHEMBL230355 | N-[(1S,2R)-2-amino-1-benzyl-3-fluor...)
Affinity DataIC50:  910nMAssay Description:Inhibition of BACE1 assessed as effect on soluble APPbeta N-terminal fragment secretion in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216177(CHEMBL230349 | N-[(1S)-1-benzyl-2-hydroxyethyl]-2-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216179(CHEMBL395084 | N-[(1S)-1-benzyl-2-hydroxyethyl]-2-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of BACE1 assessed as effect on soluble APPbeta N-terminal fragment secretion in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216178(CHEMBL394850 | N-[(1S)-1-benzyl-2-hydroxyethyl]-2-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of BACE1 assessed as effect on soluble APPbeta N-terminal fragment secretion in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed