Compile Data Set for Download or QSAR
Report error Found 484 Enz. Inhib. hit(s) with all data for entry = 12261
TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485457BDBM485457(N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(5-phen...)
Affinity DataIC50: 2.51nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485461BDBM485461(N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(5- phe...)
Affinity DataIC50: 2.95nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485467BDBM485467(N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(*S)-(2-methy...)
Affinity DataIC50: 3.98nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485460BDBM485460(N-((1R,2S)-2-acrylamidocyclopentyl)-4-oxo-5-(5- ph...)
Affinity DataIC50: 4.07nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485459BDBM485459(N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(5-phen...)
Affinity DataIC50: 4.07nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485458BDBM485458(N-((1RS,2RS)-2-Acrylamidocyclopentyl)-5-(2-methyl-...)
Affinity DataIC50: 4.17nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485600BDBM485600(N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(4-(py...)
Affinity DataIC50: 4.17nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485270BDBM485270(N-((1R,2S)-2-acrylamidocyclopentyl)-4-oxo-5-(4-phe...)
Affinity DataIC50: 4.27nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485345BDBM485345(N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(5-phe...)
Affinity DataIC50: 4.27nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485338BDBM485338(N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(6-phen...)
Affinity DataIC50: 4.47nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485333BDBM485333(N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(6-phe...)
Affinity DataIC50: 4.57nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485367BDBM485367(N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(5-phe...)
Affinity DataIC50: 4.79nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485331BDBM485331(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*R)-(4-isop...)
Affinity DataIC50: 5.01nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485349BDBM485349(N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(6-cyclobutox...)
Affinity DataIC50: 5.13nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485344BDBM485344(N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(6-phe...)
Affinity DataIC50: 5.25nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485340BDBM485340(N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(*R)-(4-isopr...)
Affinity DataIC50: 5.25nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485464BDBM485464(N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(*S)-(...)
Affinity DataIC50: 5.37nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485335BDBM485335(US10934310, Ex # 197 | N-((1R,2S)-2-Acrylamidocycl...)
Affinity DataIC50: 5.5nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485536BDBM485536(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(6-isob...)
Affinity DataIC50: 5.62nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485273BDBM485273(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(2-meth...)
Affinity DataIC50: 5.62nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485534BDBM485534(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(6-(cyc...)
Affinity DataIC50: 5.89nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485466BDBM485466(N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(2- phe...)
Affinity DataIC50: 5.89nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485355BDBM485355(N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(4-phe...)
Affinity DataIC50: 5.89nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485589BDBM485589(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(6-isop...)
Affinity DataIC50: 6.31nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485388BDBM485388(N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(6-isopropoxy...)
Affinity DataIC50: 6.46nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485337BDBM485337(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(4-meth...)
Affinity DataIC50: 6.46nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485366BDBM485366(N-((1R,2R)-2-Acrylamidocyclopentyl)-5-(*S)-(4-meth...)
Affinity DataIC50: 6.61nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485593BDBM485593(N-((1S,3R)-3-Acrylamidocyclopentyl)-5-(*S)-(4-meth...)
Affinity DataIC50: 6.76nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485386BDBM485386(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(2-methyl-4-...)
Affinity DataIC50: 6.92nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485365BDBM485365(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(2-methyl-4-...)
Affinity DataIC50: 7.41nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485332BDBM485332(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(4-meth...)
Affinity DataIC50: 7.41nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485531BDBM485531(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(2-methyl-4-...)
Affinity DataIC50: 7.41nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485284BDBM485284(N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(4-phen...)
Affinity DataIC50: 7.59nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485271BDBM485271(N-((1R,2R)-2-Acrylamidocyclopentyl)-5-(*S)-(2-meth...)
Affinity DataIC50: 7.76nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485334BDBM485334(N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(2-phen...)
Affinity DataIC50: 7.94nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485462BDBM485462(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(S)-(6-isobu...)
Affinity DataIC50: 8.13nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485359BDBM485359(5-([1,1'-Biphenyl]-3-yl)-N-((1R,2S)-2-acrylamidocy...)
Affinity DataIC50: 8.13nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485529BDBM485529(N-((1R,3S)-3-Acrylamidocyclopentyl)-5-(*S)-(6-(cyc...)
Affinity DataIC50: 8.51nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485284BDBM485284(N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(4-phen...)
Affinity DataIC50: 8.71nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485369BDBM485369(N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(6-phe...)
Affinity DataIC50: 8.71nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485532BDBM485532(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(4-((6-methy...)
Affinity DataIC50: 8.71nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485522BDBM485522(N-((1R,3S)-3-Acrylamidocyclopentyl)-5-(*S)-(4-meth...)
Affinity DataIC50: 8.91nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485341BDBM485341(N-((1R,3R)-3-Acrylamidocyclopentyl)-5-(*S)-(2-meth...)
Affinity DataIC50: 8.91nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485474BDBM485474(N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(2- ph...)
Affinity DataIC50: 9.12nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485553BDBM485553(5-(*S)-(4-Methyl-6-phenoxypyridin-3-yl)-4-oxo-N-((...)
Affinity DataIC50: 9.12nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485278BDBM485278(5-(*S)-(2-Methyl-4-phenoxyphenyl)-N-((1R,2R)-2-(2-...)
Affinity DataIC50: 9.12nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485470BDBM485470(N-((1*S,3*S)-3-Acrylamidocyclopentyl)-5-(*S)-(4-me...)
Affinity DataIC50: 9.12nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485353BDBM485353(N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(6-cyclobutox...)
Affinity DataIC50: 9.33nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485601BDBM485601(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(3-isopropyl...)
Affinity DataIC50: 9.55nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [389-659](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 485339BDBM485339(N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(*S)-(4-methy...)
Affinity DataIC50: 9.55nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

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