Compile Data Set for Download or QSAR
Report error Found 81 of affinity data for UniProtKB/TrEMBL: Q9JIA7
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514480BDBM50514480(CHEMBL4466524)
Affinity DataKi:  400nMAssay Description:Inhibition of recombinant mouse SphK2 expressed in baculovirus infected Sf9 insect cells using D-erythro-sphingosine as substrate measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407506BDBM50407506(CHEMBL4595333)
Affinity DataKi:  400nMAssay Description:Inhibition of recombinant mouse SphK2 expressed in baculovirus infected Sf9 cells using D-erythro-sphingosine and [gamma-32P]ATP as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241906BDBM241906(US9421177, VPC96047)
Affinity DataKi:  500nM ΔG°:  -37.4kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407507BDBM50407507(CHEMBL5281819)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of recombinant mouse SphK2 expressed in baculovirus infected Sf9 cells using D-erythro-sphingosine and [gamma-32P]ATP as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266438BDBM50266438(CHEMBL4095315)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of recombinant mouse SPHK2 using sphingosine as substrate in presence ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241937BDBM241937(US9421177, VPC96091)
Affinity DataKi:  1.50E+3nM ΔG°:  -34.6kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343829BDBM50343829((S)-1-(4-Dodecylbenzoyl)pyrrolidine-2-carboximidam...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241936BDBM241936(US9421177, VPC96077)
Affinity DataKi:  2.00E+3nM ΔG°:  -33.8kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241932BDBM241932(US9421177, VPC95291)
Affinity DataKi:  2.60E+3nM ΔG°:  -33.2kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343831BDBM50343831((S)-1-(4-(7-(Cyclohexylmethoxy)heptyl)benzoyl)pyrr...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241905BDBM241905(US9421177, VPC95287)
Affinity DataKi:  4.00E+3nM ΔG°:  -32.0kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241935BDBM241935(US9421177, VPC95297)
Affinity DataKi:  4.00E+3nM ΔG°:  -32.0kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241913BDBM241913(US9421177, VPC143033)
Affinity DataKi:  4.00E+3nM ΔG°:  -32.0kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343835BDBM50343835((S)-1-(4-(4-(3-(2-Cyclohexylethyl)phenyl)oxazol-2-...)
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343820BDBM50343820(N-(4-(7-((Adamantan-1-ylmethoxy)heptyl)phenyl)-1-c...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241928BDBM241928(US9421177, VPC143090)
Affinity DataKi:  4.60E+3nM ΔG°:  -31.7kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241938BDBM241938(US9421177, VPC96115)
Affinity DataKi:  5.00E+3nM ΔG°:  -31.5kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343828BDBM50343828(N-(1-Carbamimidoylcyclobutyl)-4-dodecylbenzamide H...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343830BDBM50343830((R)-1-(4-Dodecylbenzoyl)pyrrolidine-2-carboximidam...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241914BDBM241914(US9421177, VPC143081)
Affinity DataKi:  5.00E+3nM ΔG°:  -31.5kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343832BDBM50343832((S)-1-(4-(9-cyclohexylnonyl)benzoyl)pyrrolidine-2-...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241915BDBM241915(US9421177, VPC143064)
Affinity DataKi:  6.00E+3nM ΔG°:  -31.0kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343836BDBM50343836((S)-1-(4-(4-(3-(2-Cyclohexylethyl)phenyl)thiazol-2...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343818BDBM50343818(1-Carbamimidoyl-N-(4-(7-(cyclohexylmethoxy)heptyl)...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241922BDBM241922(US9421177, VPC143105)
Affinity DataKi:  7.00E+3nM ΔG°:  -30.6kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343811BDBM50343811(1-Carbamimidoyl-N-tetradecylcyclopropanecarboxamid...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241929BDBM241929(US9421177, VPC143057)
Affinity DataKi:  7.50E+3nM ΔG°:  -30.4kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359977BDBM50359977(CHEMBL1927590)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of mouse SphK2 expressed in baculovirus infected Sf9 insect cells using sphingosine and [gamma-(32)P]-ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343833BDBM50343833((S)-1-(11-(Cyclohexylmethoxy)undecanoyl)pyrrolidin...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359976BDBM50359976(CHEMBL1927588)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of mouse SphK2 expressed in baculovirus infected Sf9 insect cells using sphingosine and [gamma-(32)P]-ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343815BDBM50343815(1-Carbamimidoyl-N-(4-(9-phenylnonyl)phenyl)cyclopr...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343816BDBM50343816(1-carbamimidoyl-N-(4-(8-phenyloctyl)phenyl)cyclopr...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438143BDBM50438143(CHEMBL2409891)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse SphK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438142BDBM50438142(CHEMBL2409847)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse SphK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241908BDBM241908(US9421177, VPC96055)
Affinity DataKi:  1.00E+4nM ΔG°:  -29.7kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241919BDBM241919(US9421177, VPC143129)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241920BDBM241920(US9421177, VPC143119)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343826BDBM50343826(N-(1-carbamimidoylcyclopropyl)-4-(undecyloxy)benza...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241911BDBM241911(US9421177, VPC171167)
Affinity DataKi:  1.00E+4nM ΔG°:  -29.7kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343817BDBM50343817(1-Carbamimidoyl-N-(4-(6-(cyclohexylmethoxy)hexyl)p...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241921BDBM241921(US9421177, VPC143113)
Affinity DataKi:  1.20E+4nM ΔG°:  -29.2kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343827BDBM50343827(N-(1-Carbamimidoylcyclopropyl)-11-(cyclohexylmetho...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359979BDBM50359979(CHEMBL1927596)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of mouse SphK2 expressed in baculovirus infected Sf9 insect cells using sphingosine and [gamma-(32)P]-ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175277BDBM50175277(CHEMBL3809675)
Affinity DataKi:  1.41E+4nMAssay Description:Inhibition of recombinant mouse SphK2 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate in presence of [gamma-33P]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241939BDBM241939(US9421177, VPC143237)
Affinity DataKi:  1.50E+4nM ΔG°:  -28.6kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343823BDBM50343823(N-(1-Carbamimidoylcyclopropyl)-4-(7-(cyclohexylmet...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241927BDBM241927(US9421177, VPC14a1051)
Affinity DataKi:  1.50E+4nM ΔG°:  -28.6kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241926BDBM241926(US9421177, VPC143154)
Affinity DataKi:  1.80E+4nM ΔG°:  -28.2kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343824BDBM50343824(N-(1-Carbamimidoylcyclopropyl)-4-(7-(cyclopentylme...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine kinase 2(Mouse)
Virginia Tech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 241910BDBM241910(US9421177, VPC171147)
Affinity DataKi:  2.00E+4nM ΔG°:  -27.9kJ/moleT: 2°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

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