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Report error Found 539 of affinity data for UniProtKB/TrEMBL: P55085
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50609292(CHEMBL5273903)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PAR2 expressed in human HT-29 cells incubated for 30 mins by FLIPR Tetra system methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50091326(CHEMBL3582248)
Affinity DataIC50: 2nMAssay Description:Antagonist activity against PAR2 in human HT29 cells assessed as inhibition of SLIGKV-induced Ca2+ responses pre-incubated for 30 mins before SLIGKV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50091328(CHEMBL3582250)
Affinity DataIC50: 2nMAssay Description:Antagonist activity against PAR2 in human HT29 cells assessed as inhibition of SLIGKV-induced Ca2+ responses pre-incubated for 30 mins before SLIGKV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50503927(CHEMBL4470628)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at PAR2 in human EAhy926 cells assessed as inhibition of trypsin-induced intracellular calcium mobilization preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50274114(CHEMBL4128763)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human PAR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440872(CHEMBL2431724)
Affinity DataEC50:  4nMAssay Description:Agonist activity at PAR2 in human 16HBE14o- cells assessed as increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50091327(CHEMBL3582251)
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity against PAR2 in human HT29 cells assessed as inhibition of SLIGKV-induced Ca2+ responses pre-incubated for 30 mins before SLIGKV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50091327(CHEMBL3582251)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity against PAR2 in human HT29 cells assessed as inhibition of trypsin-induced Ca2+ responses pre-incubated for 30 mins before trypsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50091328(CHEMBL3582250)
Affinity DataIC50: 5nMAssay Description:Antagonist activity against PAR2 in human HT29 cells assessed as inhibition of trypsin-induced Ca2+ responses pre-incubated for 30 mins before trypsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50091326(CHEMBL3582248)
Affinity DataIC50: 5nMAssay Description:Antagonist activity against PAR2 in human HT29 cells assessed as inhibition of trypsin-induced Ca2+ responses pre-incubated for 30 mins before trypsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440872(CHEMBL2431724)
Affinity DataEC50:  10nMAssay Description:Agonist activity at PAR2 in human 16HBE14o- cells assessed as increase in MAPK levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50241049(CHEMBL463763 | Triptolide, 1 | triptolide)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human PAR2 expressed in human A549 cells assessed as inhibition of 2f-LIGRLO-NH2-induced NFkappaB activation by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233671(CHEMBL4100763)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233671(CHEMBL4100763)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50618279(CHEMBL5431335)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at PAR2 (unknown origin) expressed in human 1321N1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50241049(CHEMBL463763 | Triptolide, 1 | triptolide)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human PAR2 expressed in human A549 cells coexpressing TACR1 assessed as inhibition of substance P-induced IL-8 production by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50274114(CHEMBL4128763)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at PAR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440860(CHEMBL2431720)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human PAR2 expressed in African green monkey COS7 cells assessed as stimulation of inositol triphosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50412711(CHEMBL459723)
Affinity DataEC50:  25.1nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as effect on intracellular calcium mobilization by R-SAT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50412718(CHEMBL509819)
Affinity DataEC50:  25.1nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as effect on intracellular calcium mobilization by R-SAT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50412708(AC-264613 | CHEMBL494502)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as stimulation of phosphatidylinositol hydrolysis after 45 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50412708(AC-264613 | CHEMBL494502)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as increase in intracellular calcium level by bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50412708(AC-264613 | CHEMBL494502)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as stimulation of cell proliferation after 5 days by beta-galactosidase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50412708(AC-264613 | CHEMBL494502)
Affinity DataEC50:  31.6nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as effect on intracellular calcium mobilization by R-SAT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50412708(AC-264613 | CHEMBL494502)
Affinity DataEC50:  31.6nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as effect on intracellular calcium mobilization by R-SAT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233672(CHEMBL4095478)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233672(CHEMBL4095478)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50412709(CHEMBL461639)
Affinity DataEC50:  50.1nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as effect on intracellular calcium mobilization by R-SAT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50553233(CHEMBL4798456)
Affinity DataEC50:  62nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233749(CHEMBL4073996)
Affinity DataEC50:  62nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233749(CHEMBL4073996)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50553232(CHEMBL4782345)
Affinity DataEC50:  73nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233748(CHEMBL4092076)
Affinity DataEC50:  79nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233670(CHEMBL4093061)
Affinity DataEC50:  79nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233670(CHEMBL4093061)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233748(CHEMBL4092076)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50553234(CHEMBL4793975)
Affinity DataEC50:  84nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50553234(CHEMBL4793975)
Affinity DataEC50:  90nMAssay Description:Agonist activity at PAR2 in HUVEC cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50633499(CHEMBL5404935)
Affinity DataIC50: 90nMAssay Description:Antagonist activity at PAR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233668(CHEMBL4071278)
Affinity DataEC50:  95nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440853(CHEMBL236037)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440852(CHEMBL414319)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440851(CHEMBL267729)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50233668(CHEMBL4071278)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440850(CHEMBL238396)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440857(CHEMBL392253)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440856(CHEMBL398128)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440855(CHEMBL236293)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440854(CHEMBL236292)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50440863(CHEMBL2431716)
Affinity DataIC50: 100nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 20 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMed
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