Compile Data Set for Download or QSAR
Report error Found 891 of affinity data for UniProtKB/TrEMBL: Q13258
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417722(CHEMBL1644207)
Affinity DataIC50: 0.0200nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205275([(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfony...)
Affinity DataKd:  0.0300nMAssay Description:Binding affinity to human DP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417777(CHEMBL1644214)
Affinity DataIC50: 0.0501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205275([(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfony...)
Affinity DataIC50: 0.0900nMAssay Description:Activity at human DP receptor in washed platelets assessed as inhibition of PGD2-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417721(CHEMBL1644206)
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277668((R)-2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-...)
Affinity DataIC50: 0.140nMAssay Description:Antagonist activity at DP1 in washed human platelet assessed as inhibition of PGD2-induced [125I]cAMP production preincubated 10 mins before PGD2 cha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277632((S)-2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-...)
Affinity DataIC50: 0.220nMAssay Description:Antagonist activity at DP1 in washed human platelet assessed as inhibition of PGD2-induced [125I]cAMP production preincubated 10 mins before PGD2 cha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205274([(3R)-5-bromo-4-(4-chlorobenzyl)-7-fluoro-1,2,3,4-...)
Affinity DataIC50: 0.260nMAssay Description:Activity at human DP receptor in washed platelets assessed as inhibition of PGD2-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50060454((Z)-7-{(1R,2R,3S,5S)-2-[(5-Fluoro-benzo[b]thiophen...)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of [3H]PGD-2 specific binding to Prostaglandin D2 receptor from human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205276([(3R)-4-(4-chlorobenzyl)-7-fluoro-5-acetyl-1,2,3,4...)
Affinity DataIC50: 0.290nMAssay Description:Activity at human DP receptor in washed platelets assessed as inhibition of PGD2-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417759(CHEMBL1644213)
Affinity DataIC50: 0.302nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417747(CHEMBL1644245)
Affinity DataIC50: 0.302nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331736(2-((R)-9-((S)-1-(3-chlorophenyl)ethyl)-6-fluoro-8-...)
Affinity DataKi:  0.310nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277668((R)-2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-...)
Affinity DataKi:  0.320nMAssay Description:Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331733(2-((R)-9-((S)-1-(3,4-dichlorophenyl)ethyl)-6-fluor...)
Affinity DataKi:  0.330nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331738(2-((R)-6-fluoro-9-((S)-1-(4-fluorophenyl)ethyl)-8-...)
Affinity DataKi:  0.330nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331742(2-((R)-9-((R)-1-(4-chlorophenyl)-2-fluoroethyl)-6-...)
Affinity DataKi:  0.360nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331735(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-phenyl...)
Affinity DataKi:  0.360nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331732(2-((R)-9-((S)-1-(4-chloro-3-fluorophenyl)ethyl)-6-...)
Affinity DataKi:  0.380nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331739(2-((R)-9-((S)-1-(4-bromophenyl)ethyl)-6-fluoro-8-(...)
Affinity DataKi:  0.380nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331743(2-((R)-9-((R)-1-(4-chlorophenyl)-2,2-difluoroethyl...)
Affinity DataKi:  0.390nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277629(2-(9-(2,4-dichlorophenylthio)-1-isopropyl-7,8-dihy...)
Affinity DataKi:  0.390nMAssay Description:Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277631(2-(1-isopropyl-9-(2,4,5-trichlorophenylthio)-7,8-d...)
Affinity DataKi:  0.390nMAssay Description:Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417725(CHEMBL1644211)
Affinity DataIC50: 0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417771(CHEMBL1644247)
Affinity DataIC50: 0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417764(CHEMBL1644227)
Affinity DataIC50: 0.398nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50060462(CHEMBL116837 | S-5751 | (Z)-7-{(1R,2R,3S,5S)-2-[(5...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [3H]PGD-2 specific binding to Prostaglandin D2 receptor from human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331734(2-((R)-9-((S)-1-(4-chloro-2-fluorophenyl)ethyl)-6-...)
Affinity DataKi:  0.410nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50128750(7-{2-[(5-Fluoro-benzo[b]thiophene-3-carbonyl)-amin...)
Affinity DataIC50: 0.420nMAssay Description:Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]PGD-2 binding to human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  0.430nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417773(CHEMBL1644253)
Affinity DataIC50: 0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417726(CHEMBL1644212)
Affinity DataIC50: 0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417723(CHEMBL1644208)
Affinity DataIC50: 0.501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331740(2-((R)-9-((S)-1-(4-cyanophenyl)ethyl)-6-fluoro-8-(...)
Affinity DataKi:  0.510nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277577(2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-dihy...)
Affinity DataKi:  0.530nMAssay Description:Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205275([(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfony...)
Affinity DataKi:  0.570nMAssay Description:Binding affinity to human DP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205278([(3R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(met...)
Affinity DataKi:  0.570nMAssay Description:Inhibition of prostaglandin DP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50594971(TREPROSTINIL | CHEBI:50861 | Treprostinil | Trespr...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human DP1 expressed in human 1321N1 cells assessed as increase in cAMP level incubated for 20 mins measured after 60 mins additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277632((S)-2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-...)
Affinity DataKi:  0.640nMAssay Description:Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277630(2-(1-isopropyl-9-(4-(trifluoromethyl)phenylthio)-7...)
Affinity DataKi:  0.670nMAssay Description:Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277575(2-(9-(4-chlorophenylthio)-1-isopropyl-7,8-dihydro-...)
Affinity DataKi:  0.710nMAssay Description:Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277573(2-(1-(cyclopropylmethyl)-9-(3,4-dichlorophenylthio...)
Affinity DataKi:  0.740nMAssay Description:Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331731(2-((R)-9-((S)-1-(4-chlorophenyl)ethyl)-6-fluoro-8-...)
Affinity DataKi:  0.75nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417728(CHEMBL1644217)
Affinity DataIC50: 0.794nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277540(2-(1-cyclopropyl-9-(3,4-dichlorophenylthio)-7,8-di...)
Affinity DataKi:  0.800nMAssay Description:Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50152512({1-[4-(7-Fluoro-4-methyl-3,4-dihydro-2H-benzo[1,4]...)
Affinity DataIC50: 0.810nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277576(2-(10-(3,4-dichlorophenylthio)-1-isopropyl-6,7,8,9...)
Affinity DataKi:  0.880nMAssay Description:Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277443((+/-)-2-(5-(4-chlorophenylthio)-4-isopropyl-6,7,8,...)
Affinity DataKi:  0.880nMAssay Description:Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50331730((+/-)-2-(9-(4-chlorobenzyl)-6-fluoro-8-(methylsulf...)
Affinity DataKi:  0.890nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417763(CHEMBL1644224)
Affinity DataIC50: 0.891nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Displayed 1 to 50 (of 891 total ) | Next | Last >>
Jump to: