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TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 209861BDBM209861(TAK-901 | 5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N...)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of Aurora B/INCENP (unknown origin) assessed as affinity constant pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315769BDBM50315769(GSK-1070916 | 4-[3-(4-N,N-Dimethylcarbamylaminophe...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of human Aurora B/INCENP pre-incubated for 30 mins before 5-FAM-PKAtide substrate addition and measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 47224BDBM47224(US9073917, 2-inventive)
Affinity DataIC50: 1nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Ev que, 86600 Celle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277545BDBM50277545(Alisertib | MLN8237 | CHEMBL483158 | 4-(9-chloro-7...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAurora kinase C/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315769BDBM50315769(GSK-1070916 | 4-[3-(4-N,N-Dimethylcarbamylaminophe...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human Aurora C/human GST-tagged INCENP pre-incubated for 30 mins before 5-FAM-PKAtide substrate addition and measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175305BDBM50175305(CHEMBL3600873)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 167515BDBM167515(US9073917, 12- comparative)
Affinity DataIC50: 3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 167510BDBM167510(US9073917, 7- comparative)
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 167506BDBM167506(US9073917, 1-inventive)
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 117012BDBM117012(US8637532, 739)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574278BDBM50574278(CHEMBL4854144)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 167507BDBM167507(US9073917, 4- comparative)
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 167508BDBM167508(US9073917, 5- comparative)
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 167512BDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50: 8nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 167513BDBM167513(US9073917, 10- comparative)
Affinity DataIC50: 9nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 116525BDBM116525(US8637532, 211)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 167516BDBM167516(US9073917, 13- comparative)
Affinity DataIC50: 10nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 167509BDBM167509(US9073917, 6- comparative)
Affinity DataIC50: 13nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 209861BDBM209861(TAK-901 | 5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora B/INCENP (unknown origin) pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244953BDBM50244953(CHEMBL4063500)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged Aurora B//N-terminal GST-tagged INCENP (821-end residues) expressed in baculovirus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 167511BDBM167511(US9073917, 8- comparative)
Affinity DataIC50: 21nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase C/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244953BDBM50244953(CHEMBL4063500)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged Aurora-C (35-end residues)/N-terminal GST-tagged INCENP (821-end residues) expressed in baculo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574272BDBM50574272(CHEMBL4875416)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574268BDBM50574268(CHEMBL4851020)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574269BDBM50574269(CHEMBL4857965)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574270BDBM50574270(CHEMBL4855657)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574279BDBM50574279(CHEMBL4869229)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574274BDBM50574274(CHEMBL4860970)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574275BDBM50574275(CHEMBL4856439)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 167512BDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50: 107nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198027BDBM50198027(CHEMBL3921246)
Affinity DataIC50: 150nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574277BDBM50574277(CHEMBL4871106)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574271BDBM50574271(CHEMBL4876446)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467633BDBM50467633(CHEMBL4291945)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetInner centromere protein(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  204nMAssay Description:Binding affinity to human INCENP incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574276BDBM50574276(CHEMBL4846712)
Affinity DataIC50: 233nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574273BDBM50574273(CHEMBL4871853)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198044BDBM50198044(CHEMBL3903187)
Affinity DataIC50: 830nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574280BDBM50574280(CHEMBL4853030)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198086BDBM50198086(CHEMBL3985313)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198082BDBM50198082(CHEMBL3904239)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198081BDBM50198081(CHEMBL3915550)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198045BDBM50198045(CHEMBL3975102)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198080BDBM50198080(CHEMBL3932394)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetInner centromere protein(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  3.05E+3nMAssay Description:Binding affinity to human INCENP incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50465482BDBM50465482(CHEMBL4288628)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50465481BDBM50465481(CHEMBL4291472)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60452BDBM60452(US9073917, 3-comparative)
Affinity DataIC50: 3.80E+3nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Ev que, 86600 Celle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467663BDBM50467663(CHEMBL4285153)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50465478BDBM50465478(CHEMBL4286130)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
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