BDBM50380140 CHEMBL2011155::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 10

SMILES: NS(=O)(=O)c1cc(ccc1Cl)C(=O)CSc1ncccn1

InChI Key: InChIKey=ZHRHWGNFAKOKSF-UHFFFAOYSA-N

Data: 32 Kd  12 K_off  6 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 50 hits for monomerid = 50380140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 13 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	1.20E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	5.50E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	4.10E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	2.00E+6	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	8.80E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	1.20E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.160	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.430	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0220	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0730	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	333	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0730	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Horse)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	1.00E-8	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0220	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Rhesus macaque)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.430	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.55E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	333	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	714	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50380140 (CHEMBL2011155 | carbonic anhydrase (CA) inhibitors...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair