34 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Benzo[b]thiophene-2-carboxamide derivatives as potent urotensin-II receptor antagonists.
Korea Research Institute of Chemical Technology
Urotensin II((4-11)) Azasulfuryl Peptides: Synthesis and Biological Activity.
University of Montreal
De Novo Conception of Small Molecule Modulators Based on Endogenous Peptide Ligands: Pyrrolodiazepin-2-one¿-Turn Mimics That Differentially Modulate Urotensin II Receptor-Mediated Vasoconstriction ex Vivo.
University of Montreal
Lead optimization of P5U and urantide: discovery of novel potent ligands at the urotensin-II receptor.
University of Naples&Quot;Federico Ii&Quot
Synthesis and SAR of thieno[3,2-b]pyridinyl urea derivatives as urotensin-II receptor antagonists.
Korea Research Institute of Chemical Technology
Development and pharmacological characterization of conformationally constrained urotensin II-related peptide agonists.
Laval University
Deconstruction of sulfonamide inhibitors of the urotensin receptor (UT) and design and synthesis of benzylamine and benzylsulfone antagonists.
Boehringer Ingelheim Pharmaceuticals
Aminoalkoxybenzyl pyrrolidines as novel human urotensin-II receptor antagonists.
Glaxosmithkline
Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists.
National Institute of Neuroscienc
New insight into the binding mode of peptide ligands at Urotensin-II receptor: structure-activity relationships study on P5U and urantide.
University of Naples Federico Ii
N-alkyl-5H-pyrido[4,3-b]indol-1-amines and derivatives as novel urotensin-II receptor antagonists.
Glaxosmithkline
Structure-activity relationships of a novel series of urotensin II analogues: identification of a urotensin II antagonist.
University of Rouen
Identification of new agonists of urotensin-II from a cyclic peptide library.
Prism Bio. Lab.
Development of potent and selective small-molecule human Urotensin-II antagonists.
Glaxosmithkline
Urotensin-II receptor modulators as potential drugs.
Johnson & Johnson Pharmaceutical Research & Development
Nonpeptide urotensin-II receptor antagonists: a new ligand class based on piperazino-phthalimide and piperazino-isoindolinone subunits.
Johnson & Johnson Pharmaceutical Research & Development
Urotensin-II receptor antagonists: synthesis and SAR of N-cyclic azaalkyl benzamides.
Glaxosmithkline
Potent and selective small-molecule human urotensin-II antagonists with improved pharmacokinetic profiles.
Glaxosmithkline
Phenylpiperidine-benzoxazinones as urotensin-II receptor antagonists: synthesis, SAR, and in vivo assessment.
Johnson & Johnson Pharmaceutical Research & Development
Architecture of the human urotensin II receptor: comparison of the binding domains of peptide and non-peptide urotensin II agonists.
Università
Urolinin: The First Linear Peptidic Urotensin-II Receptor Agonist.
Charit£-Universit£Tsmedizin Berlin
Identification of nonpeptidic urotensin II receptor antagonists by virtual screening based on a pharmacophore model derived from structure-activity relationships and nuclear magnetic resonance studies on urotensin II.
Aventis Pharma Germany
Insights into the Molecular Determinants Involved in Urocontrin and Urocontrin A Action.
Laval University
Functional Selectivity Revealed by N-Methylation Scanning of Human Urotensin II and Related Peptides.
University of Naples "Federico Ii
Synthesis and SAR of 5-aryl-furan-2-carboxamide derivatives as potent urotensin-II receptor antagonists.
Korea Research Institute of Chemical Technology
Design, parallel synthesis and SAR of novel urotensin II receptor agonists.
G£Teborg University
Novel potent and efficacious nonpeptidic urotensin II receptor agonists.
G£Teborg University
Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954).
Acadia Pharmaceuticals
A new, potent urotensin II receptor peptide agonist containing a Pen residue at the disulfide bridge.
University of Naples Federico Ii
Discovery of New Allosteric Modulators of the Urotensinergic System through Substitution of the Urotensin II-Related Peptide (URP) Phenylalanine Residue.
Laval University