BDBM85043 CAS_149017-66-3::CHEMBL69234::NSC_6093163::PPADS

SMILES Cc1nc(N=Nc2ccc(cc2S(O)(=O)=O)S(O)(=O)=O)c(COP(O)(O)=O)c(C=O)c1O

InChI Key InChIKey=PNFZSRRRZNXSMF-UHFFFAOYSA-N

Data  4 KI  15 IC50  14 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 85043   

TargetP2X purinoceptor 2(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X2 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  240nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 6(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of inward ion current elicited by ATP at rat P2X6 receptor (mutant type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  99nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of inward ion current elicited by ATP at rat P2X4 receptor (mutant type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  2.75E+4nMAssay Description:Inhibition of inward ion current elicited by ATP at human P2X4 receptor (mutant type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor(Mus musculus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of inward ion current elicited by ATP at mouse P2X4 receptor (mutant type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 6(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of inward ion current elicited by ATP at rat P2X6 receptor (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of inward ion current elicited by ATP at rat P2X4 receptor (wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of 10 nM 2-MeSADP-stimulated phospholipase C in turkey erythrocyte membranes using [3H]-inositolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  9.85E+4nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  2.40E+5nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X3 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed