Compile Data Set for Download or QSAR
Report error Found 94 Enz. Inhib. hit(s) with Target = 'Cyclin-K/Cyclin-dependent kinase 13'
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367676BDBM50367676(CHEMBL4160662)
Affinity DataKd:  8.60nMAssay Description:Binding affinity to human CDK13 (694 to 1039 residues)/CyclinK (1 to 267 residues) expressed in baculovirus infected in Sf9 cells by Biolayer interfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 479007BDBM479007(US10894788, Example 47 | US10894788, Example 138 |...)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) using pS7-CTD peptide and ATP as substrate incubated for 120 mins by ADP-Glo reagent based luminescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367676BDBM50367676(CHEMBL4160662)
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK13 (1 to 1512 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597426BDBM50597426(CHEMBL5169449)
Affinity DataIC50: 12nMAssay Description:Inhibition of GST-tagged human CDK13/Cyclin K expressed in Sf9 cells using RBER-IRStide peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662094BDBM50662094(CHEMBL6144395)
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK13/cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 729426BDBM729426(N-(5-(3-benzyl-1-(((1r,4r)-4-((5-cyanopyridin-2-yl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK13/cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594507BDBM50594507(CHEMBL5203891)
Affinity DataKd:  17nMAssay Description:Binding affinity to human CDK13 (694 to 1039 residues)/CyclinK (1 to 267 residues) expressed in baculovirus infected in Sf9 cells by Biolayer interfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367676BDBM50367676(CHEMBL4160662)
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK13/cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808400BDBM808400(7-methyl-3-(2- {[(3S)-piperidin- 3-yl]amino}-5- (t...)
Affinity DataIC50: 20nMAssay Description:Cryopreserved human PBMCs were obtained from AllCells (cat# PB003F). After thawing/dilution protocols using RPMI medium supplemented with 5% FBS (hea...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139171BDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: 21nMAssay Description:Inhibition of GST-tagged human CDK13/Cyclin K expressed in Sf9 cells using RBER-IRStide peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597425BDBM50597425(CHEMBL5194202)
Affinity DataIC50: 22nMAssay Description:Inhibition of GST-tagged human CDK13/Cyclin K expressed in Sf9 cells using RBER-IRStide peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597424BDBM50597424(CHEMBL5187378)
Affinity DataIC50: 22nMAssay Description:Inhibition of GST-tagged human CDK13/Cyclin K expressed in Sf9 cells using RBER-IRStide peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 729437BDBM729437(N-(5-(3-benzyl-1-((1r,4R)-4-((5-cyanopyridin-2-yl)...)
Affinity DataIC50: 22nMAssay Description:Inhibition of CDK13/cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540079BDBM50540079(CHEMBL4632717)
Affinity DataIC50: 22nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808414BDBM808414(3-(2-{[(3S)-6,6- dimethylpiperidin- 3-yl]amino}-5-...)
Affinity DataIC50: 25nMAssay Description:Cryopreserved human PBMCs were obtained from AllCells (cat# PB003F). After thawing/dilution protocols using RPMI medium supplemented with 5% FBS (hea...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808400BDBM808400(7-methyl-3-(2- {[(3S)-piperidin- 3-yl]amino}-5- (t...)
Affinity DataIC50: 27.5nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808401BDBM808401(4-[5-(2-methyl- 2H-1,2,3,4- tetrazol-5-yl)-1H- pyr...)
Affinity DataIC50: 27.5nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808414BDBM808414(3-(2-{[(3S)-6,6- dimethylpiperidin- 3-yl]amino}-5-...)
Affinity DataIC50: 27.5nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528815BDBM50528815(CHEMBL4468670)
Affinity DataIC50: 29nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528813BDBM50528813(CHEMBL4163879 | US20250101023, Example THZ531)
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539904BDBM50539904(CHEMBL4647764)
Affinity DataIC50: 49nMAssay Description:Inhibition of human CDK13/cyclin K using Pol2-CTD as substrate by [gamma-33P]ATP-based radioisotope filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50573506BDBM50573506(CHEMBL4861833)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 57nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK13 (1 to 1512 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528813BDBM50528813(CHEMBL4163879 | US20250101023, Example THZ531)
Affinity DataIC50: 63nMAssay Description:Inhibition of CDK13/cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808425BDBM808425(3-[2-({4- azaspiro[2.5]octan- 6-yl}amino)-5- (trif...)
Affinity DataIC50: 65nMAssay Description:The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 729432BDBM729432(N-(5-(3-benzyl-1-((1r,4r)-4-((5-cyanopyridin-2-yl)...)
Affinity DataIC50: 67nMAssay Description:Inhibition of CDK13/cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597419BDBM50597419(CHEMBL5182767)
Affinity DataIC50: 67nMAssay Description:Inhibition of GST-tagged human CDK13/Cyclin K expressed in Sf9 cells using RBER-IRStide peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50540080BDBM50540080(CHEMBL4648857)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant CDK13/Cyclin K (unknown origin) expresssed in baculovirus infected insect cells using peptide substrate incubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528813BDBM50528813(CHEMBL4163879 | US20250101023, Example THZ531)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant CDK13/Cyclin K (unknown origin) extracted from baculovirus infected insect cells using Pol II CTD-peptide as substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528813BDBM50528813(CHEMBL4163879 | US20250101023, Example THZ531)
Affinity DataIC50: 69nMAssay Description:Competitive irreversible inhibition of CDK13/cyclinK (unknown origin) in presence of Km ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528813BDBM50528813(CHEMBL4163879 | US20250101023, Example THZ531)
Affinity DataIC50: 69nMAssay Description:Inhibition of CDK13/human cyclin K expressed in baculovirus-infected insect cells using pol2 CTD-peptide substrate and [gammaP]ATP by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 729429BDBM729429(N-(5-(3-benzyl-1-((1r,4r)-4-((5-cyanopyridin-2-yl)...)
Affinity DataIC50: 74nMAssay Description:Inhibition of CDK13/cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666855BDBM50666855(CHEMBL6176879)
Affinity DataIC50: 75nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) using pS7-CTD peptide and ATP as substrate incubated for 120 mins by ADP-Glo reagent based luminescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666853BDBM50666853(CHEMBL6163371)
Affinity DataIC50: 76nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) using pS7-CTD peptide and ATP as substrate incubated for 120 mins by ADP-Glo reagent based luminescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 729428BDBM729428(N-(5-(3-benzyl-1-((1r,4r)-4-((5-cyanopyridin-2-yl)...)
Affinity DataIC50: 79nMAssay Description:Inhibition of CDK13/cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666851BDBM50666851(CHEMBL6176040)
Affinity DataIC50: 79nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) using pS7-CTD peptide and ATP as substrate incubated for 120 mins by ADP-Glo reagent based luminescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808416BDBM808416(3-(2-{[(3S)-6,6- dimethylpiperidin- 3-yl]amino}-5-...)
Affinity DataIC50: 81nMAssay Description:Cryopreserved human PBMCs were obtained from AllCells (cat# PB003F). After thawing/dilution protocols using RPMI medium supplemented with 5% FBS (hea...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 729434BDBM729434(US20250100994, Compound YJZ6093)
Affinity DataIC50: 84nMAssay Description:Inhibition of CDK13/cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666856BDBM50666856(CHEMBL6174809)
Affinity DataIC50: 95nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) using pS7-CTD peptide and ATP as substrate incubated for 120 mins by ADP-Glo reagent based luminescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 729425BDBM729425(N-(3-(3-benzyl-1-((1r,4r)-4-((5-cyanopyridin-2-yl)...)
Affinity DataIC50: 99nMAssay Description:Inhibition of CDK13/cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666850BDBM50666850(CHEMBL6176452)
Affinity DataIC50: 107nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) using pS7-CTD peptide and ATP as substrate incubated for 120 mins by ADP-Glo reagent based luminescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666851BDBM50666851(CHEMBL6176040)
Affinity DataIC50: 111nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged CDK13/N-terminal FLAG and C-terminal His-tagged Cyclin K expressed in HEP Sf9 cells using ATP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50573513BDBM50573513(CHEMBL4866757)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597407BDBM50597407(CHEMBL5191136)
Affinity DataIC50: 122nMAssay Description:Inhibition of GST-tagged human CDK13/Cyclin K expressed in Sf9 cells using RBER-IRStide peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50573511BDBM50573511(CHEMBL4864697)
Affinity DataIC50: 123nMAssay Description:Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808416BDBM808416(3-(2-{[(3S)-6,6- dimethylpiperidin- 3-yl]amino}-5-...)
Affinity DataIC50: 125nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808434BDBM808434(3-(2-{[(6S)-4- azaspiro[2.5]octan- 6-yl]amino}-5- ...)
Affinity DataIC50: 125nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808425BDBM808425(3-[2-({4- azaspiro[2.5]octan- 6-yl}amino)-5- (trif...)
Affinity DataIC50: 125nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50573515BDBM50573515(CHEMBL4853887)
Affinity DataIC50: 127nMAssay Description:Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCyclin-K/Cyclin-dependent kinase 13(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808434BDBM808434(3-(2-{[(6S)-4- azaspiro[2.5]octan- 6-yl]amino}-5- ...)
Affinity DataIC50: 152nMAssay Description:The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

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