Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 4 subunit B'
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470392BDBM50470392(CHEMBL4283208)
Affinity DataIC50: 3nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470400BDBM50470400(CHEMBL4289998)
Affinity DataIC50: 4nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470403BDBM50470403(CHEMBL4294467)
Affinity DataIC50: 4nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470394BDBM50470394(CHEMBL4281775)
Affinity DataIC50: 8nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470395BDBM50470395(CHEMBL4279313)
Affinity DataIC50: 9nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470405BDBM50470405(CHEMBL4289650)
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393079BDBM50393079(CHEMBL2152855 | US9040542, 23)
Affinity DataKi:  12nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 Par E subunit by ATPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470393BDBM50470393(CHEMBL4291061)
Affinity DataIC50: 12nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470404BDBM50470404(CHEMBL4279382)
Affinity DataIC50: 14nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470402BDBM50470402(CHEMBL4278317)
Affinity DataIC50: 21nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470399BDBM50470399(CHEMBL4286573)
Affinity DataIC50: 23nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470406BDBM50470406(CHEMBL4295081)
Affinity DataIC50: 24nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470398BDBM50470398(CHEMBL4286232)
Affinity DataIC50: 25nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393080BDBM50393080(CHEMBL2152856)
Affinity DataKi:  30nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 Par E subunit by ATPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470396BDBM50470396(CHEMBL4293447)
Affinity DataIC50: 49nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058509BDBM50058509(CHEMBL3329317)
Affinity DataIC50: 86nMAssay Description:Inhibition of Staphylococcus aureus ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393080BDBM50393080(CHEMBL2152856)
Affinity DataIC50: 150nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 Par E subunit by ATPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173879BDBM50173879(CHEMBL3810359)
Affinity DataIC50: 183nMAssay Description:Inhibition of Staphylococcus aureus DNA parE ATPase activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470401BDBM50470401(CHEMBL4290062)
Affinity DataIC50: 200nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470397BDBM50470397(CHEMBL4294536)
Affinity DataIC50: 400nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006565BDBM50006565(CHEMBL3235085)
Affinity DataIC50: 700nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173878BDBM50173878(CHEMBL3809316)
Affinity DataIC50: 746nMAssay Description:Inhibition of Staphylococcus aureus DNA parE ATPase activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058511BDBM50058511(CHEMBL3329318)
Affinity DataIC50: 780nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058510BDBM50058510(CHEMBL3329319)
Affinity DataIC50: 800nMAssay Description:Inhibition of Staphylococcus aureus ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058509BDBM50058509(CHEMBL3329317)
Affinity DataIC50: 940nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470407BDBM50470407(CHEMBL4286625)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226181BDBM50226181(Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of Staphylococcus aures ParE using pBR322 DNA as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058510BDBM50058510(CHEMBL3329319)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625844BDBM50625844(CHEMBL5422204)
Affinity DataIC50: 5.38E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625845BDBM50625845(CHEMBL5427814)
Affinity DataIC50: 6.67E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625842BDBM50625842(CHEMBL5419490)
Affinity DataIC50: 6.76E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625843BDBM50625843(CHEMBL5407144)
Affinity DataIC50: 7.81E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550961BDBM50550961(CHEMBL4764715)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Staphylococcus aures ParE using pBR322 DNA as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed