Report error Found 214 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, kainate 3'
Affinity DataKi: 3.84nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR7More data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H](2S, 4R)-4-MeGlu (SYM-2081) from GluK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5.69nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR7More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Ability to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 32.8nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR7More data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou...More data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Compound was tested for binding affinity against human Ionotropic glutamate receptor ionotropic kainate 3 in HEK293 cells using [3H]kainate as radiol...More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 57.3nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR7More data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:In vitro activity at Ionotropic glutamate receptor using cortical wedge assays in rat brain synaptosomaMore data for this Ligand-Target Pair
Affinity DataKi: 123nMAssay Description:Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou...More data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Potency on Ionotropic glutamate receptor kainate in dorsal root ganglion cellsMore data for this Ligand-Target Pair
Affinity DataKi: 142nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 185nMAssay Description:Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou...More data for this Ligand-Target Pair
Affinity DataKi: 199nMAssay Description:Displacement of [3H]SYM from rat recombinant GluR7A expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 217nMAssay Description:Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou...More data for this Ligand-Target Pair
Affinity DataKi: 239nMAssay Description:Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou...More data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Displacement of [3H]-KA from rat GluK3More data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:In vitro activity at Ionotropic glutamate receptor using cortical wedge assays in rat brain synaptosomaMore data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou...More data for this Ligand-Target Pair
Affinity DataKi: 376nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR7More data for this Ligand-Target Pair
Affinity DataKi: 376nMAssay Description:Displacement of [3H]SYM2081 from rat cloned iGluR7More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Binding affinity against Ionotropic glutamate receptor using ACPD sensitive [3H]- glutamate displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
Affinity DataKi: 423nMAssay Description:Ability to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Displacement of [3H]SYM2081 from rat iGluR7 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 494nMAssay Description:Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou...More data for this Ligand-Target Pair
Affinity DataKi: 494nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR7More data for this Ligand-Target Pair
Affinity DataKi: 518nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 617nMAssay Description:Ability to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 617nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
Affinity DataKi: 680nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Compound was tested in vitro for binding affinity against Ionotropic glutamate receptor kainate using [3H]kainate as the radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 789nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
Affinity DataKi: 789nMAssay Description:Ability to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 1.01E+3nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR7More data for this Ligand-Target Pair
Affinity DataKi: 1.02E+3nMAssay Description:Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+3nMAssay Description:Binding affinity against Ionotropic glutamate receptor using ACPD sensitive [3H]- glutamate displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
Affinity DataKi: 1.19E+3nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.38E+3nMAssay Description:Displacement of [3H]SYM from rat recombinant GluR7A expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.67E+3nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR7More data for this Ligand-Target Pair
Affinity DataKi: 1.74E+3nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK3a expressed in sS9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+3nMAssay Description:Binding affinity against Ionotropic glutamate receptor using ACPD sensitive [3H]- glutamate displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+3nMAssay Description:Binding affinity against Ionotropic glutamate receptor using ACPD sensitive [3H]- glutamate displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
Affinity DataKi: 2.15E+3nMAssay Description:Displacement of [3H]SYM2081 from recombinant homomeric rat GluK3 receptor expressed in baculovirus infected Sf9 insect cell membranesMore data for this Ligand-Target Pair









































