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Found 209 with Last Name = 'guy breitenbucher' and Initial = 'j'
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254419(CHEMBL511391 | N2-(2,6-dichlorophenyl)-N7-(4-(pyrr...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254080((3,5-dichloro-4-(7-(4-(trifluoromethyl)phenylamino...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254419(CHEMBL511391 | N2-(2,6-dichlorophenyl)-N7-(4-(pyrr...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254080((3,5-dichloro-4-(7-(4-(trifluoromethyl)phenylamino...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254325(CHEMBL469302 | N7-(4-tert-butylphenyl)-N2-(2,6-dic...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254077(CHEMBL517566 | N2-(2,6-dichlorophenyl)-N5-isobutyl...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254154(CHEMBL468470 | N2-(2-chloro-6-methylphenyl)-N7-(4-...)
Affinity DataIC50:  1.60nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254077(CHEMBL517566 | N2-(2,6-dichlorophenyl)-N5-isobutyl...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254326(2-(4-(2-(2,6-dichlorophenylamino)thiazolo[5,4-d]py...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254421(CHEMBL465990 | N7-(3-chloro-4-(trifluoromethyl)phe...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560624(CHEMBL4747373)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of rat FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560624(CHEMBL4747373)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254078(CHEMBL460373 | N5-(cyclopropylmethyl)-N2-(2,6-dich...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254421(CHEMBL465990 | N7-(3-chloro-4-(trifluoromethyl)phe...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254136(CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254078(CHEMBL460373 | N5-(cyclopropylmethyl)-N2-(2,6-dich...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254324(CHEMBL512298 | N2-(2,6-dichlorophenyl)-N7-(4-isopr...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254376(CHEMBL467851 | N2-(2,6-dichlorophenyl)-N7-(4-(meth...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560652(CHEMBL4777574)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of rat FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560616(CHEMBL4755710)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254322(CHEMBL467007 | N2-(2,6-dichlorophenyl)-N7-(6-(trif...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254136(CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]RTX from rat TRPV1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254376(CHEMBL467851 | N2-(2,6-dichlorophenyl)-N7-(4-(meth...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560621(CHEMBL4758524)
Affinity DataIC50:  5nMAssay Description:Inhibition of rat FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254136(CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of low pH-induced calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254153(CHEMBL511589 | N2-(2,6-dimethylphenyl)-N7-(4-(trif...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560616(CHEMBL4755710)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254154(CHEMBL468470 | N2-(2-chloro-6-methylphenyl)-N7-(4-...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254054(CHEMBL462276 | N2-(2,6-dichlorophenyl)-N5-isopropy...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254420(CHEMBL517044 | N7-(3-chloro-4-(trifluoromethyl)phe...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560640(CHEMBL4788479)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of rat FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254324(CHEMBL512298 | N2-(2,6-dichlorophenyl)-N7-(4-isopr...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560653(CHEMBL4764954)
Affinity DataIC50:  11nMAssay Description:Inhibition of rat FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254079(CHEMBL459320 | N2-(2,6-dichlorophenyl)-N5-(2-morph...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254325(CHEMBL469302 | N7-(4-tert-butylphenyl)-N2-(2,6-dic...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560654(CHEMBL4795579)
Affinity DataIC50:  12nMAssay Description:Inhibition of rat FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254375(CHEMBL467639 | N2-(2,6-dichlorophenyl)-N7-(4-(meth...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254136(CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50253983(CHEMBL462688 | N2-(2,6-dichlorophenyl)-5-(pyrrolid...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254054(CHEMBL462276 | N2-(2,6-dichlorophenyl)-N5-isopropy...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254173(CHEMBL465986 | N2-o-tolyl-N7-(4-(trifluoromethyl)p...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254322(CHEMBL467007 | N2-(2,6-dichlorophenyl)-N7-(6-(trif...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254114(CHEMBL461658 | N-(4-(trifluoromethyl)phenyl)-7-(3-...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254029(CHEMBL460146 | N2-(2,6-dichlorophenyl)-5-morpholin...)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560620(CHEMBL4760472)
Affinity DataIC50:  17nMAssay Description:Inhibition of human FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254136(CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of low pH-induced calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560628(CHEMBL4787317)
Affinity DataIC50:  20nMAssay Description:Inhibition of rat FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560622(CHEMBL4760330)
Affinity DataIC50:  20nMAssay Description:Inhibition of rat FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50254420(CHEMBL517044 | N7-(3-chloro-4-(trifluoromethyl)phe...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50560630(CHEMBL4790902)
Affinity DataIC50:  21nMAssay Description:Inhibition of rat FAAH1 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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