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Found 178 with Last Name = 'benkova' and Initial = 'm'
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50555835(CHEMBL4752175)
Affinity DataKi:  0.456nMAssay Description:Noncompetitive inhibition of human acetylcholinesterase assessed as affinity towards free enzyme using acetylthiocholine iodide as substrate measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50555837(CHEMBL4747577)
Affinity DataKi:  8.30nMAssay Description:Mixed inhibition of human butyrylcholinesterase assessed as affinity towards free enzyme using butyrylthiocholine iodide as substrate measured by Ell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50555837(CHEMBL4747577)
Affinity DataKi:  76nMAssay Description:Mixed inhibition of human butyrylcholinesterase assessed as affinity towards enzyme-substrate complex using butyrylthiocholine iodide as substrate me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465901(CHEMBL4285826)
Affinity DataKi:  1.20E+4nMAssay Description:Reversible inhibition of recombinant human recombinant AChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465900(CHEMBL4281350)
Affinity DataKi:  2.10E+4nMAssay Description:Reversible inhibition of recombinant human recombinant AChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465902(CHEMBL4277895)
Affinity DataKi:  2.20E+4nMAssay Description:Reversible inhibition of recombinant human recombinant AChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465903(CHEMBL4289221)
Affinity DataKi:  2.40E+4nMAssay Description:Reversible inhibition of recombinant human recombinant AChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50020522(1-(((4-carbamoylpyridinium-1-yl)methoxy)methyl)-2-...)
Affinity DataKi:  2.50E+4nMAssay Description:Reversible inhibition of recombinant human recombinant AChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465904(CHEMBL4284764)
Affinity DataKi:  3.60E+4nMAssay Description:Reversible inhibition of recombinant human recombinant AChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465899(CHEMBL4292643)
Affinity DataKi:  4.20E+4nMAssay Description:Reversible inhibition of recombinant human recombinant AChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50333782(4-(aminocarbonyl)-1-(3-{4-[(E)-(hydroxyimino)methy...)
Affinity DataKi:  7.30E+4nMAssay Description:Reversible inhibition of human erythrocytic AChE using acetylthiocholine iodide as substrate measured up to 2 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50333783((E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomet...)
Affinity DataKi:  9.00E+4nMAssay Description:Reversible inhibition of human erythrocytic AChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50025010(CHEMBL116379)
Affinity DataKi:  1.10E+5nMAssay Description:Reversible inhibition of human erythrocytic AChE using acetylthiocholine iodide as substrate measured up to 2 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465901(CHEMBL4285826)
Affinity DataKi:  1.40E+5nMAssay Description:Reversible inhibition of human plasma BChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM234367(Pralidoxime (3))
Affinity DataKi:  1.80E+5nMAssay Description:Reversible inhibition of recombinant human recombinant AChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465902(CHEMBL4277895)
Affinity DataKi:  1.87E+5nMAssay Description:Reversible inhibition of human plasma BChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465900(CHEMBL4281350)
Affinity DataKi:  1.95E+5nMAssay Description:Reversible inhibition of human plasma BChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50020522(1-(((4-carbamoylpyridinium-1-yl)methoxy)methyl)-2-...)
Affinity DataKi:  2.15E+5nMAssay Description:Reversible inhibition of human plasma BChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465904(CHEMBL4284764)
Affinity DataKi:  2.65E+5nMAssay Description:Reversible inhibition of human plasma BChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465899(CHEMBL4292643)
Affinity DataKi:  2.73E+5nMAssay Description:Reversible inhibition of human plasma BChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50465903(CHEMBL4289221)
Affinity DataKi:  2.94E+5nMAssay Description:Reversible inhibition of human plasma BChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM234367(Pralidoxime (3))
Affinity DataKi:  3.90E+5nMAssay Description:Reversible inhibition of human plasma BChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50333783((E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomet...)
Affinity DataKi:  9.10E+5nMAssay Description:Reversible inhibition of human plasma BChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523376(CHEMBL4589980)
Affinity DataIC50:  0.00800nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50028685(CHEMBL3356536)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523394(CHEMBL4448188)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50099602(CHEMBL3343931)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523387(CHEMBL4556281)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523391(CHEMBL4449083)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523377(CHEMBL4559593)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523376(CHEMBL4589980)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523387(CHEMBL4556281)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523377(CHEMBL4559593)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523375(CHEMBL4555818)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM8987(6-chloro-1,2,3,4-tetrahydroacridin-9-amine | 6-chl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523388(CHEMBL4556575)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523389(CHEMBL4559477)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523383(CHEMBL4438120)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523393(CHEMBL4466307)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523375(CHEMBL4555818)
Affinity DataIC50:  52nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523379(CHEMBL4467355)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50265253((S)-2-amino-3-(1H-indol-3-yl)-N-(2-(1,2,3,4-tetrah...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523373(CHEMBL4552440)
Affinity DataIC50:  62nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523371(CHEMBL4456435)
Affinity DataIC50:  64nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523386(CHEMBL4541558)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523382(CHEMBL4563209)
Affinity DataIC50:  74nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523382(CHEMBL4563209)
Affinity DataIC50:  76nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523371(CHEMBL4456435)
Affinity DataIC50:  76nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM50523380(CHEMBL4586157)
Affinity DataIC50:  78nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defense

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
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