Compile Data Set for Download or QSAR
maximum 50k data
Found 24 with Last Name = 'barbas' and Initial = 'cf'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50:  0.370nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 MGC26-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50:  0.430nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 YU2-induced cell-cell fusion between viral envelope p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50446234(CHEMBL3109175)
Affinity DataIC50:  0.960nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197001(CHEMBL238539 | N-[2'-(isoxazol-5-ylsulfamoyl)-4-ox...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 92RW-induced cell-cell fusion between viral envelope ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197003(CHEMBL241460 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-(2...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50:  1.60nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50446232(CHEMBL3109173)
Affinity DataIC50:  2.60nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50446231(CHEMBL3109172)
Affinity DataIC50:  3nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197002(CHEMBL268201 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197000(CHEMBL429019 | N-(35-{[4-(3,5-dioxohexyl)phenyl]ca...)
Affinity DataIC50:  7.70nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197004(3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenyl...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50196999(CHEMBL413001 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)
Affinity DataIC50:  21.6nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50446233(CHEMBL3109174)
Affinity DataIC50:  27nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197005(CHEMBL436821 | N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexy...)
Affinity DataIC50:  44.9nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50446236(CHEMBL3109177)
Affinity DataIC50:  360nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50446235(CHEMBL3109176)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197003(CHEMBL241460 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-(2...)
Affinity DataIC50:  1.11E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197002(CHEMBL268201 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)
Affinity DataIC50:  1.91E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197000(CHEMBL429019 | N-(35-{[4-(3,5-dioxohexyl)phenyl]ca...)
Affinity DataIC50:  4.51E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197004(3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenyl...)
Affinity DataIC50:  4.69E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50196999(CHEMBL413001 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)
Affinity DataIC50:  4.92E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197001(CHEMBL238539 | N-[2'-(isoxazol-5-ylsulfamoyl)-4-ox...)
Affinity DataIC50:  6.00E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197005(CHEMBL436821 | N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed