TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.370nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 MGC26-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 YU2-induced cell-cell fusion between viral envelope p...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.960nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 92RW-induced cell-cell fusion between viral envelope ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 21.6nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
Affinity DataIC50: 44.9nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity against CCR5 receptor in human TZM-bl cells assessed as inhibition of HIV-1 JR-FL-induced cell-cell fusion between viral envelope...More data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.91E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.51E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.69E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.92E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair