Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.720nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard University
Curated by ChEMBL
Harvard University
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 19nMAssay Description:α7 nAChR: The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affin...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard University
Curated by ChEMBL
Harvard University
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard University
Curated by ChEMBL
Harvard University
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard University
Curated by ChEMBL
Harvard University
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 26nMAssay Description:α7 nAChR: The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affin...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 29nMAssay Description:α7 nAChR: The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affin...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:h-5HT3: In brief, Chinese Hamster Ovary (CHO) cells stably expressing human 5-HT3 serotonin receptors, grown to confluence in 175 cm2 flasks. Followi...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:h-5HT3: In brief, Chinese Hamster Ovary (CHO) cells stably expressing human 5-HT3 serotonin receptors, grown to confluence in 175 cm2 flasks. Followi...More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 36nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 37nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard University
Curated by ChEMBL
Harvard University
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
Affinity DataKi: 43.5nMAssay Description:h-5HT3: In brief, Chinese Hamster Ovary (CHO) cells stably expressing human 5-HT3 serotonin receptors, grown to confluence in 175 cm2 flasks. Followi...More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:h-5HT3: In brief, Chinese Hamster Ovary (CHO) cells stably expressing human 5-HT3 serotonin receptors, grown to confluence in 175 cm2 flasks. Followi...More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:h-5HT3: In brief, Chinese Hamster Ovary (CHO) cells stably expressing human 5-HT3 serotonin receptors, grown to confluence in 175 cm2 flasks. Followi...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 47nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard University
Curated by ChEMBL
Harvard University
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard University
Curated by ChEMBL
Harvard University
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 54.5nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:h-5HT3: In brief, Chinese Hamster Ovary (CHO) cells stably expressing human 5-HT3 serotonin receptors, grown to confluence in 175 cm2 flasks. Followi...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 58nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 59.5nMAssay Description:α7 nAChR: The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affin...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard University
Curated by ChEMBL
Harvard University
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 61nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard University
Curated by ChEMBL
Harvard University
Curated by ChEMBL
Affinity DataKi: 64nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair