TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.00240nMAssay Description:Inhibition of HIV1 recombinant protease after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0310nMAssay Description:Inhibition of HIV1 recombinant protease after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(GUINEA PIG)
Fujisawa Pharmaceutical
Curated by PDSP Ki Database
Fujisawa Pharmaceutical
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sumitomo Dainippon Pharma.
Curated by ChEMBL
Sumitomo Dainippon Pharma.
Curated by ChEMBL
Affinity DataKi: 0.0910nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sumitomo Dainippon Pharma.
Curated by ChEMBL
Sumitomo Dainippon Pharma.
Curated by ChEMBL
Affinity DataKi: 0.0940nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2More data for this Ligand-Target Pair
Affinity DataKi: 0.109nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Binding affinity to human dopamine D1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sumitomo Dainippon Pharma.
Curated by ChEMBL
Sumitomo Dainippon Pharma.
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sumitomo Dainippon Pharma.
Curated by ChEMBL
Sumitomo Dainippon Pharma.
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.154nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium m...More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Binding affinity to rat Dopamine receptor D2 expressesd in CHO cells was determined using [125 I ] iodosulpride as radioligandMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Inhibitory activity of the compound against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Inhibition of HIV1 recombinant protease after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity to human dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.211nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.221nMAssay Description:Agonist activity at human recombinant KOR expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataKi: 0.221nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.225nMAssay Description:Displacement of [3H]U69593 from guinea pig cerebellum kappa opioid receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(GUINEA PIG)
Fujisawa Pharmaceutical
Curated by PDSP Ki Database
Fujisawa Pharmaceutical
Curated by PDSP Ki Database
Affinity DataKi: 0.240nMAssay Description:Binding affinity of the compound to rat Dopamine receptor D3 expressed in CHO cells was determined using [125 I] iodosulpride as radioligandMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Inhibitory activity of the compound against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.265nMAssay Description:Agonist activity at human recombinant KOR expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataKi: 0.274nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.282nMAssay Description:Adenosine A1 receptor binding using [3H]DPCPX in rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.301nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.308nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.313nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.313nMAssay Description:Displacement of [3H]DPDPE from human recombinant DOR expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.325nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.336nMAssay Description:Displacement of [3H]DPDPE from human recombinant DOR expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.356nMAssay Description:Displacement of [3H]DPDPE from human recombinant DOR expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.362nMAssay Description:Displacement of [3H]U-69,593 from human recombinant KOR expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.368nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.383nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
Fujisawa Pharmaceutical
Curated by PDSP Ki Database
Fujisawa Pharmaceutical
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sumitomo Dainippon Pharma.
Curated by ChEMBL
Sumitomo Dainippon Pharma.
Curated by ChEMBL
Affinity DataKi: 0.420nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.455nMAssay Description:Displacement of [3H]DAMGO from human recombinant MOR expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.458nMAssay Description:Displacement of [3H]DPDPE from human recombinant DOR expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.458nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Inhibitory activity of the compound against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.479nMAssay Description:Displacement of [3H]DPDPE from human recombinant DOR expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Binding affinity to human dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Adenosine A1 receptor binding using [3H]DPCOX in rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Adenosine A1 receptor binding using [3H]DPCPX in human cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2More data for this Ligand-Target Pair