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Found 320 with Last Name = 'middya' and Initial = 's'
LigandPNGBDBM50323728(2-((4-amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyrazo...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
LigandPNGBDBM50323728(2-((4-amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyrazo...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of PI3Kdelta (unknown origin) in presence of [gamma-32P]ATP by phosphorimaging assayMore data for this Ligand-Target Pair
LigandPNGBDBM50201717(CHEMBL3907591)
Affinity DataIC50:  3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201728(CHEMBL3914552)
Affinity DataIC50:  4nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201716(CHEMBL3942550)
Affinity DataIC50:  7nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201720(CHEMBL3896635)
Affinity DataIC50:  8nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201721(CHEMBL3964073)
Affinity DataIC50:  8nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388180(CHEMBL2057912)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of BTK (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201723(CHEMBL3905578)
Affinity DataIC50:  9nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201721(CHEMBL3964073)
Affinity DataIC50:  12nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201727(CHEMBL3924678)
Affinity DataIC50:  13nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201729(CHEMBL3923573)
Affinity DataIC50:  14nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50:  24nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50:  24nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201717(CHEMBL3907591)
Affinity DataIC50:  27nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201724(CHEMBL3983045)
Affinity DataIC50:  32nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201729(CHEMBL3923573)
Affinity DataIC50:  33nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50323728(2-((4-amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyrazo...)
Affinity DataIC50:  33nMAssay Description:Inhibition of PI3Kgamma (unknown origin) in presence of [gamma-32P]ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201725(CHEMBL3948373)
Affinity DataIC50:  35nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201719(CHEMBL3957821)
Affinity DataIC50:  43nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50:  47nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201726(CHEMBL3897842)
Affinity DataIC50:  47nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201718(CHEMBL3925929)
Affinity DataIC50:  55nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201718(CHEMBL3925929)
Affinity DataIC50:  55nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201716(CHEMBL3942550)
Affinity DataIC50:  61nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201720(CHEMBL3896635)
Affinity DataIC50:  67nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201724(CHEMBL3983045)
Affinity DataIC50:  84nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201723(CHEMBL3905578)
Affinity DataIC50:  86nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201725(CHEMBL3948373)
Affinity DataIC50:  104nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201728(CHEMBL3914552)
Affinity DataIC50:  142nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201719(CHEMBL3957821)
Affinity DataIC50:  172nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201718(CHEMBL3925929)
Affinity DataIC50:  176nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50201718(CHEMBL3925929)
Affinity DataIC50:  176nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate after 20 mins by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387452(N3-(3-Chloro-4- fluorophenyl)- 5-methoxy-7- methyl...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387576(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)fu...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387577(N3-(3-chloro-4- fluorophenyl)- 7-(3,4- difluorophe...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387578(N3-(3-Chloro-4- fluorophenyl)- 7-(2,3,4- trifluoro...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387579(7-Bromo-N3-(3- chloro-4- fluorophenyl)- 5-methoxy-...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387580(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)-5...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387581(N3-(3-chloro-4- fluorophenyl)- 7-(4- fluorophenyl)...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387582(4-(2-amino-3- ((3-chloro-4- fluorophenyl) amino)-5...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387585(N3-(3-chloro-4- fluorophenyl)- 7-fluorofuro [2,3-c...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387586(5-Chloro-N3- (3-chloro-4- fluorophenyl) furo[2,3-c...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387587(N3-(3-chloro-4- fluorophenyl)- 6-nitrobenzo- furan...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387588(N3-(3-Chloro-4- fluorophenyl)- 5-fluoro-7- (pyridi...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387589(N3-(3-Chloro-4- fluorophenyl)- 5-fluorofuro [2,3-c...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387590(2-Amino-3-((2- chlorophenyl) amino)furo [2,3-c]pyr...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387591(2-Amino-3- ((4-fluoro-3- (trifluoro- methyl)phenyl...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387592(N3-(3,4- difluoro- phenyl)-7- (pyridin-4- yl)furo[...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Curadev Pharma

US Patent
LigandPNGBDBM387603(N3-(3,4- Difluoro- phenyl)-5- fluoro-7- (pyridin-4...)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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