TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate after 20 mins by Dixon and Cornish-Bowden methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 685nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate after 20 mins by Dixon and Cornish-Bowden methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate after 20 mins by Dixon and Cornish-Bowden methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate assessed as dissociation constant for enzyme-inhibitor-substrate complex after 20 mins...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate after 20 mins by Dixon and Cornish-Bowden methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 1.52E+4nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate after 20 mins by Dixon and Cornish-Bowden methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 1.92E+5nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate assessed as dissociation constant for enzyme-inhibitor-substrate complex after 20 mins...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate after 20 mins by Dixon and Cornish-Bowden methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate after 20 mins by Dixon and Cornish-Bowden methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataIC50: 1.63E+4nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate after 20 mins by Dixon and Cornish-Bowden methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataIC50: 1.87E+4nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate after 20 mins by Dixon and Cornish-Bowden methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataIC50: 3.12E+4nMAssay Description:Mixed type inhibition of human NPP1 using pNP-TMP as substrate after 20 mins by Dixon and Cornish-Bowden methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+5nMAssay Description:Antagonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced increase in intracellula...More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at human P2Y6 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at P2Y6 receptor expressed in human 1321N1 cells assessed as inositol phosphate accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at P2Y6 receptor expressed in human 1321N1 cells assessed as inositol phosphate accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 4.5nMAssay Description:Agonist activity at rat brain P2Y1R transfected in HEK293 cells assessed as induction of intracellular calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...More data for this Ligand-Target Pair
Affinity DataEC50: 3.68E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...More data for this Ligand-Target Pair
Affinity DataEC50: 2.90E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...More data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...More data for this Ligand-Target Pair
Affinity DataEC50: 6.70E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 950nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 74nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+4nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 760nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 850nMAssay Description:Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
Affinity DataEC50: 2.20E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
Affinity DataEC50: 2.01E+4nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
Affinity DataEC50: 1.12E+4nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
Affinity DataEC50: 4.30E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
Affinity DataEC50: 900nMAssay Description:Agonist activity at human GFP-tagged P2Y4 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair