TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: 221nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: 282nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: 338nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: 447nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: 583nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: 1.93E+3nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: 7.90E+3nMAssay Description:Inhibition of human Phosphodiesterase 7More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 5 isolated from human tracheaMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bos taurus)
Glaxo Wellcome Research
Curated by ChEMBL
Glaxo Wellcome Research
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of bovine Phosphodiesterase 2More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics
Curated by ChEMBL
Fount Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair