Compile Data Set for Download or QSAR
maximum 50k data
Found 275 with Last Name = 'xu' and Initial = 'yj'
LigandPNGBDBM50374977(CHEMBL270849)
Affinity DataIC50:  9nMAssay Description:Inhibition of cloned CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468557(CHEMBL4294787)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50309525(2-(5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-6-m...)
Affinity DataIC50:  10nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50309525(2-(5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-6-m...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human p38alpha after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375063(CHEMBL255607)
Affinity DataIC50:  10nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374956(CHEMBL272978)
Affinity DataIC50:  12nMAssay Description:Inhibition of cloned CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375073(CHEMBL402340)
Affinity DataIC50:  13nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50309524(2-(6-chloro-5-(4-(4-fluorobenzyl)piperidine-1-carb...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human p38alpha after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50132378(((1S,3R)-4-Benzyl-2,5-dimethyl-piperazin-1-yl)-(6-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50132378(((1S,3R)-4-Benzyl-2,5-dimethyl-piperazin-1-yl)-(6-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375061(CHEMBL271648)
Affinity DataIC50:  21nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)
Affinity DataIC50:  30nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
LigandPNGBDBM50375062(CHEMBL402533)
Affinity DataIC50:  32nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374982(CHEMBL403446)
Affinity DataIC50:  34nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374982(CHEMBL403446)
Affinity DataIC50:  34nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375072(CHEMBL403337)
Affinity DataIC50:  38nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374954(CHEMBL271045)
Affinity DataIC50:  42nMAssay Description:Inhibition of cloned CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375071(CHEMBL270032)
Affinity DataIC50:  46nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468570(CHEMBL4290513)
Affinity DataIC50:  50nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50309531(2-(5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-6-m...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human p38alpha after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468565(CHEMBL4277125)
Affinity DataIC50:  60nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50374963(CHEMBL402428)
Affinity DataIC50:  64nMAssay Description:Inhibition of cloned CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374965(CHEMBL255617)
Affinity DataIC50:  66nMAssay Description:Inhibition of cloned CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175932(1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  75nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50309529(2-(3-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-2-m...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human p38alpha after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50309528(2-(6-chloro-5-(4-(4-fluorobenzyl)piperidine-1-carb...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human p38alpha after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375077(CHEMBL430412)
Affinity DataIC50:  110nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374956(CHEMBL272978)
Affinity DataIC50:  110nMAssay Description:Inhibition of CaMK2delta-mediated vimentin phosphorylation in human HL2 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM15240(4-[1-methyl-2-(piperidin-4-yl)-4-[3-(trifluorometh...)
Affinity DataIC50:  110nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
LigandPNGBDBM50375070(CHEMBL411724)
Affinity DataIC50:  110nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175938(1,3-bis(4-(7-methyl-1H-benzo[d]imidazol-2-yl)pheny...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375064(CHEMBL402152)
Affinity DataIC50:  150nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175931(1-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3-(4-(7-met...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175936(1,3-bis(4-(6-methyl-1H-benzo[d]imidazol-2-yl)pheny...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375069(CHEMBL271426)
Affinity DataIC50:  170nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374966(CHEMBL402524)
Affinity DataIC50:  170nMAssay Description:Inhibition of cloned CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
LigandPNGBDBM50374989(CHEMBL412302)
Affinity DataIC50:  180nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374989(CHEMBL412302)
Affinity DataIC50:  180nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375080(CHEMBL270141)
Affinity DataIC50:  190nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375067(CHEMBL271043)
Affinity DataIC50:  190nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374972(CHEMBL403766)
Affinity DataIC50:  210nMAssay Description:Inhibition of cloned CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175811(CHEMBL200215 | N-(4-{[4-(1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374997(CHEMBL256827)
Affinity DataIC50:  230nMAssay Description:Inhibition of CaMK2delta using 3 weeks old stock solution of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374952(CHEMBL403054)
Affinity DataIC50:  240nMAssay Description:Inhibition of cloned CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175939(1,3-bis-[4-(1H-benzoimidazol-2-yl)phenyl]urea | CH...)
Affinity DataIC50:  270nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375066(CHEMBL256460)
Affinity DataIC50:  280nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374988(CHEMBL408434)
Affinity DataIC50:  280nMAssay Description:Inhibition of CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175813(CHEMBL200831 | N-(4-{[5-(1H-benzoimidazol-2-yl)-py...)
Affinity DataIC50:  290nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50374960(CHEMBL255633)
Affinity DataIC50:  290nMAssay Description:Inhibition of cloned CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 275 total ) | Next | Last >>
Jump to: