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Found
58
Enz. Inhib. hit(s) with all data for entry = 4712
Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM82247
(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
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Ki: 0.300nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50010301
(SKF 83566 | CHEMBL324017 | 8-Bromo-3-methyl-5-phen...)
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Ki: 0.300nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM82247
(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
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Affinity Data
Ki: 0.350nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50010301
(SKF 83566 | CHEMBL324017 | 8-Bromo-3-methyl-5-phen...)
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Affinity Data
Ki: 0.400nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50008735
(CHEMBL8514 | BUTACLAMOL,d- | (+)-3-(tert-butyl)-(3...)
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Ki: 3nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50026957
((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
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Ki: 4nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50026957
((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
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Ki: 8nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
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Ki: 14nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM60917
(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
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Ki: 15nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
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Ki: 21nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50008735
(CHEMBL8514 | BUTACLAMOL,d- | (+)-3-(tert-butyl)-(3...)
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Ki: 27nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 27nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM60917
(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
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Ki: 28nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM82247
(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
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Ki: 35nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM82247
(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
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Ki: 41nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 48nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Ki: 73nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50004822
(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
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Ki: 100nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Ki: 100nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81872
(NSC_161309 | CAS_161309 | Ergocryptine, beta)
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Ki: 113nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Ki: 133nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Ki: 141nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50004822
(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
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Ki: 150nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21395
(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
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Ki: 190nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Ki: 220nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
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Ki: 228nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Ki: 250nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Ki: 300nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001955
(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
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Ki: 363nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81993
(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)
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Ki: 454nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50012994
(SKF-76783 | cid_11957529 | CHEMBL538542 | NPA,(+) ...)
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Ki: 530nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50012994
(SKF-76783 | cid_11957529 | CHEMBL538542 | NPA,(+) ...)
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Ki: 645nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81993
(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)
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Ki: 672nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001955
(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
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Ki: 680nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM60917
(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
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Ki: 800nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81871
(NSC_16 | CAS_16 | ADTN, (+))
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Ki: 909nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50028421
(Permax | CHEMBL1275 | Pergolide | 9-Methylsulfanyl...)
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Ki: 918nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50054062
(CHEMBL104383 | N-0437 | 6-[Propyl-(2-thiophen-2-yl...)
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Ki: 986nM
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Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81777
(NPA,(+) | NPA | CAS_132-66-1 | NSC_8594 | NPA,(-))
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Ki: 1.14E+3nM
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Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50028421
(Permax | CHEMBL1275 | Pergolide | 9-Methylsulfanyl...)
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Ki: 1.36E+3nM
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In Depth
Date in BDB:
11/18/2011
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Article
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81777
(NPA,(+) | NPA | CAS_132-66-1 | NSC_8594 | NPA,(-))
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Ki: 1.82E+3nM
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In Depth
Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM60917
(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
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Ki: 1.82E+3nM
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In Depth
Date in BDB:
11/18/2011
Entry Details
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50054062
(CHEMBL104383 | N-0437 | 6-[Propyl-(2-thiophen-2-yl...)
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Ki: 2.17E+3nM
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In Depth
Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
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Ki: 2.34E+3nM
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In Depth
Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21395
(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
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Ki: 2.50E+3nM
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In Depth
Date in BDB:
11/18/2011
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Article
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Ki: 3.00E+3nM
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In Depth
Date in BDB:
11/18/2011
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Ki: 4.50E+3nM
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In Depth
Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81871
(NSC_16 | CAS_16 | ADTN, (+))
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Ki: 4.60E+3nM
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In Depth
Date in BDB:
11/18/2011
Entry Details
Article
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PubMed
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Target
D(1B) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50007518
(3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmet...)
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Ki: >1.00E+4nM
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In Depth
Date in BDB:
11/18/2011
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Target
D(1A) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM11638
(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
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Ki: >1.00E+4nM
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In Depth
Date in BDB:
11/18/2011
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