Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50003267
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431893(ARRY-520 | CHEMBL2347655)
Affinity DataIC50:  6nMAssay Description:Inhibition of microtubule-stimulated Eg5 ATPase activity in human HL-60 cells after 48 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50463316(KF 89617 | KF-89617 | Kf89617 | LY 2523355 | LY-25...)
Affinity DataIC50:  26nMAssay Description:Inhibition of microtubule-stimulated human Eg5 ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468755(CHEMBL4283764)
Affinity DataIC50:  493nMAssay Description:Inhibition of N-terminal His6-tagged microtubule-stimulated ATPase activity of human Eg5 motor domain (1 to 368 residues) expressed in Escherichia co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468755(CHEMBL4283764)
Affinity DataIC50:  580nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  740nMAssay Description:Inhibition of N-terminal His6-tagged microtubule-stimulated ATPase activity of human Eg5 motor domain (1 to 368 residues) expressed in Escherichia co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  740nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468752(CHEMBL3735751)
Affinity DataIC50:  840nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468759(CHEMBL1391655)
Affinity DataIC50:  950nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of microtubule-stimulated recombinant human Eg5 ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468750(CHEMBL3735259)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468758(CHEMBL1369692)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468763(CHEMBL4283187)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468751(CHEMBL4287823)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468754(CHEMBL1565660)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468762(CHEMBL3735499)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468757(CHEMBL4288387)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468760(CHEMBL1373238)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468765(CHEMBL1599833)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468753(CHEMBL1712931)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM90458(MLS000693062 | N-(4-acetyl-5-methyl-5-pyridin-2-yl...)
Affinity DataIC50:  3.72E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468749(CHEMBL4279312)
Affinity DataIC50:  4.11E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468761(CHEMBL4283892)
Affinity DataIC50:  4.69E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468764(CHEMBL4288725)
Affinity DataIC50:  5.39E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468756(CHEMBL4293322)
Affinity DataIC50:  5.99E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataKd:  665nMAssay Description:Binding affinity to N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468755(CHEMBL4283764)
Affinity DataKd:  220nMAssay Description:Binding affinity to N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed