Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 50007936
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514120(CHEMBL3407553)
Affinity DataKi:  400nMAssay Description:Competitive inhibition of UCHL1 in human H1299 cells using Ub-AMC substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514118(CHEMBL4590454)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of USP7 (unknown origin) using Ub-Rh110 substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCOP9 signalosome complex subunit 5(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514114(CHEMBL4528101)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of CSN5 (unknown origin) using fluorescence-labeled CRL substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 4(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514113(CHEMBL4593739)
Affinity DataIC50:  50nMAssay Description:Inhibition of USP4 in human U2OS using Ub-TAMRA substrate by Ub-Rhodamine fluorescent intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514119(CHEMBL4515625)
Affinity DataIC50:  52nMAssay Description:Inhibition of USP7 C-terminal domain (unknown origin) (208 to 1102 residues) expressed in Sf9 cells using monoubiquitinated ubiquitin-rhodamine subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCOP9 signalosome complex subunit 5(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514115(CHEMBL4447716)
Affinity DataIC50:  60nMAssay Description:Inhibition of CSN5 (unknown origin) using fluorescence-labeled CRL substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514122(CHEMBL4548694)
Affinity DataIC50:  90nMAssay Description:Inhibition of human full-length USP7 (1 to 1102 amino acids) expressed in Escherichia coli BL21(DE3) incubated 30 mins by Ubiquitin-AMC assayMore data for this Ligand-Target Pair
TargetSTAM-binding protein(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514117(CHEMBL4586347)
Affinity DataIC50:  330nMAssay Description:Inhibition of human STAMBP expressed in Sf21 cells pre-incubated for 20 mins before Ubiquitinated NALP7 substrate addition and measured after 1 hr by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 28(Homo sapiens)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514121(CHEMBL4442615)
Affinity DataIC50:  600nMAssay Description:Inhibition of USP28 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50250947(CHEMBL4092976)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of recombinant USP7 (unknown origin) by mass spectrometry based activity assayMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514116(CHEMBL4458718)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-AMC substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50437694(CHEMBL1410015)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of full-length human USP14 using Ub-AMC substrateMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514113(CHEMBL4593739)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of USP7 in human U2OS using Ub-TAMRA substrate by Ub-Rhodamine fluorescent intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed