Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50006375
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499290BDBM50499290(CHEMBL3734797)
Affinity DataIC50: 2nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499298BDBM50499298(CHEMBL3734847)
Affinity DataIC50: 3nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499292BDBM50499292(CHEMBL3734764)
Affinity DataIC50: 4nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499286BDBM50499286(CHEMBL3735388)
Affinity DataIC50: 23nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499289BDBM50499289(CHEMBL3735235)
Affinity DataIC50: 60nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 360598BDBM360598(methyl 3-(8-((3-(2,3- dichlorophenyl)ureido)methyl...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499288BDBM50499288(CHEMBL3736485)
Affinity DataIC50: 140nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 360543BDBM360543(N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)sp...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499297BDBM50499297(CHEMBL3736366)
Affinity DataIC50: 300nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499297BDBM50499297(CHEMBL3736366)
Affinity DataIC50: 400nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499295BDBM50499295(CHEMBL3735591)
Affinity DataIC50: 500nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499285BDBM50499285(CHEMBL3736092)
Affinity DataIC50: 540nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499287BDBM50499287(CHEMBL3734770)
Affinity DataIC50: 600nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499285BDBM50499285(CHEMBL3736092)
Affinity DataIC50: 760nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499287BDBM50499287(CHEMBL3734770)
Affinity DataIC50: 800nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499290BDBM50499290(CHEMBL3734797)
Affinity DataIC50: 800nMAssay Description:Inhibition of voltage-gated calcium channel (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499289BDBM50499289(CHEMBL3735235)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499290BDBM50499290(CHEMBL3734797)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499296BDBM50499296(CHEMBL3736151)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499290BDBM50499290(CHEMBL3734797)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499291BDBM50499291(CHEMBL3735666)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499295BDBM50499295(CHEMBL3735591)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499290BDBM50499290(CHEMBL3734797)
Affinity DataIC50: 2.34E+3nMAssay Description:Displacement of [35S]-MK-0499 from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499286BDBM50499286(CHEMBL3735388)
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499292BDBM50499292(CHEMBL3734764)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 360543BDBM360543(N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)sp...)
Affinity DataIC50: 4.77E+3nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499288BDBM50499288(CHEMBL3736485)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499296BDBM50499296(CHEMBL3736151)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499290BDBM50499290(CHEMBL3734797)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse MGAT2 by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499290BDBM50499290(CHEMBL3734797)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499298BDBM50499298(CHEMBL3734847)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499290BDBM50499290(CHEMBL3734797)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse DGAT1 by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499290BDBM50499290(CHEMBL3734797)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DGAT1 by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499290BDBM50499290(CHEMBL3734797)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MGAT2 by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499285BDBM50499285(CHEMBL3736092)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DGAT1 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499293BDBM50499293(CHEMBL3735532)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499290BDBM50499290(CHEMBL3734797)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499294BDBM50499294(CHEMBL3735953)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499291BDBM50499291(CHEMBL3735666)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 360598BDBM360598(methyl 3-(8-((3-(2,3- dichlorophenyl)ureido)methyl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MGAT2 (unknown origin) by CPM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499294BDBM50499294(CHEMBL3735953)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DGAT2 expressed in Sf9 cell membranes assessed as triolein formation by LC/MS/MS analysis using oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50499285BDBM50499285(CHEMBL3736092)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GPAT1 (unknown origin) by CPM assay using glycerol-3-phosphate and oleoyl-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed