Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50035176
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358043BDBM50358043(GW-5074 | CHEMBL1794051)
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095423BDBM50095423(methyl 5-tert-butyl-3-(3-phenylureido)thiophene-2-...)
Affinity DataIC50: 290nMAssay Description:Inhibition of Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105619BDBM50105619(1-(5-tert-butylisoxazol-3-yl)-3-(4-phenoxyphenyl)u...)
Affinity DataIC50: 360nMAssay Description:Inhibition of Escherichia coli derived Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105619BDBM50105619(1-(5-tert-butylisoxazol-3-yl)-3-(4-phenoxyphenyl)u...)
Affinity DataIC50: 540nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105601BDBM50105601(methyl 5-tert-butyl-3-(3-(5-methyl-1,3,4-thiadiazo...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095399BDBM50095399(methyl 5-tert-butyl-3-(3-p-tolylureido)thiophene-2...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105621BDBM50105621(5-tert-Butyl-3-[3-(5-cyclopropyl-[1,3,4]thiadiazol...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105597BDBM50105597(5-tert-Butyl-3-[3-(5-ethyl-[1,3,4]thiadiazol-2-yl)...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095396BDBM50095396(5-tert-Butyl-3-(3-p-tolyl-ureido)-furan-2-carboxyl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095428BDBM50095428(5-tert-Butyl-3-(3-p-tolyl-ureido)-1H-pyrrole-2-car...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105606BDBM50105606(5-tert-Butyl-3-[3-(4-methyl-thiophen-2-yl)-ureido]...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105620BDBM50105620(5-tert-Butyl-3-[3-(5-methyl-thiophen-2-yl)-ureido]...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105612BDBM50105612(methyl 5-isopropyl-3-(3-p-tolylureido)thiophene-2-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095403BDBM50095403(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095414BDBM50095414(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105599BDBM50105599(5-Bromomethyl-3-(3-p-tolyl-ureido)-thiophene-2-car...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105615BDBM50105615(5-tert-Butyl-3-[3-(5-trifluoromethyl-[1,3,4]thiadi...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105613BDBM50105613(methyl 5-tert-butyl-3-(3-(1-methyl-1H-pyrazol-3-yl...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095420BDBM50095420(5-tert-Butyl-3-[3-(4-chloro-phenyl)-ureido]-thioph...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105598BDBM50105598(methyl 5-tert-butyl-3-(3-(1-ethyl-1H-pyrrol-3-yl)u...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095394BDBM50095394(5-tert-Butyl-3-[3-(3,4-dichloro-phenyl)-ureido]-fu...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105596BDBM50105596(5-tert-Butyl-3-[3-(1-ethyl-1H-pyrazol-3-yl)-ureido...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105614BDBM50105614(5-tert-Butyl-3-[3-(1-isopropyl-1H-pyrrol-3-yl)-ure...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105604BDBM50105604(methyl 5-tert-butyl-3-(3-(5-tert-butyl-1,3,4-thiad...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105602BDBM50105602(5-tert-Butyl-3-[3-(1-propyl-1H-pyrrol-3-yl)-ureido...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105610BDBM50105610(5-tert-Butyl-3-(3-thiophen-2-yl-ureido)-thiophene-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105607BDBM50105607(methyl 5-tert-butyl-3-(3-(3,4-dichlorophenyl)ureid...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105617BDBM50105617(3-[3-(1-Benzyl-1H-pyrazol-3-yl)-ureido]-5-tert-but...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105611BDBM50105611(1-(2-Aminomethyl-5-tert-butyl-thiophen-3-yl)-3-p-t...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095411BDBM50095411(methyl 5-tert-butyl-3-(3-(4-hydroxyphenyl)ureido)t...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105618BDBM50105618(5-tert-butyl-N,N-dimethyl-3-(3-p-tolylureido)thiop...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105600BDBM50105600(5-tert-Butyl-3-[3-(3,4-dimethyl-phenyl)-ureido]-th...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105608BDBM50105608(methyl 5-tert-butyl-3-(3-(1-isopropyl-1H-pyrazol-3...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095423BDBM50095423(methyl 5-tert-butyl-3-(3-phenylureido)thiophene-2-...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095395BDBM50095395(methyl 3-(3-(4-aminophenyl)ureido)-5-tert-butylthi...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105605BDBM50105605(5-tert-Butyl-3-[3-(1-propyl-1H-pyrazol-3-yl)-ureid...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105616BDBM50105616(5-tert-Butyl-3-(3-m-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105603BDBM50105603(methyl 5-tert-butyl-3-(3-(3,4-dichlorophenyl)ureid...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105609BDBM50105609(5-tert-Butyl-3-[3-(3-chloro-phenyl)-ureido]-thioph...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed