Compile Data Set for Download or QSAR
Report error Found 334 Enz. Inhib. hit(s) with all data for entry = 558
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278614BDBM278614((2E)-3-(1-{[3-(2,6- Dichlorophenyl)-5-(3- methoxyo...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278561BDBM278561( (2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(propan-2-yl...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278633BDBM278633(US10040791, Example 95)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278569BDBM278569( (2E)-3-(1-{[5-(2-Methoxypropan-2-yl)-3-(2,4,6-tri...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278628BDBM278628((2E)-3-(1-{[5-(1-Aminocyclobutyl)-3-(2,4,6-trichlo...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278540BDBM278540( (2E)-3-(3-Methyl-1-{[5-(3-methyloxetan-3-yl)-3-(2...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278541BDBM278541( (2E)-3-(1-{[5-(3-Methoxyoxetan-3-yl)-3-(2,4,6-tri...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278566BDBM278566( (2E)-3-(1-{[3-(2,6-Dichloro-3-fluorophenyl)-5-(pr...)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278542BDBM278542( (2E)-3-(1-{[5-(3-Methoxyoxetan-3-yl)-3-(2,4,6-tri...)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278615BDBM278615((2E)-3-(1-{[3-(2,6- Dichlorophenyl)-5-(2- methylox...)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278624BDBM278624((2E)-[1-({5-[1- (Methylamino)cyclopropyl]-3- (2,4,...)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278546BDBM278546( (2E)-[1-{[5-(3-Methyloxetan-3-yl)-3-(2,4,6-trichl...)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278587BDBM278587((2E)-3-(1-{[3-(2,6-Dichloro-4- fluorophenyl)-5-(2-...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278630BDBM278630(US10040791, Example 92)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278671BDBM278671((2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(dimethylamin...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278703BDBM278703( (2E)-3-(1-Methyl-3-{[5-(1-methylcyclopropyl)-3-(2...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278595BDBM278595((2E)-3-(1-{[5-(1- Methoxycyclopropyl)-3-(2,4,6- tr...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278539BDBM278539((2E)-3-(1-{[5-(3-Methyloxetan-3-yl)-3-(2,4,6-trich...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278702BDBM278702((2E)-3-(3-[5-tert-Butyl-3-(2,4,6-trichlorophenyl)-...)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278543BDBM278543( (2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(3-ethyloxet...)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278697BDBM278697( (2E)-3-[1-({5-[(5R)7-Acryloyl-5-methyl-4,7-diazas...)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278545BDBM278545( (2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(2-hydroxypr...)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278588BDBM278588((2E)-3-(7-Fluoro-1-{[5-(2- fluoropropan-2-yl)-3-(2...)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278565BDBM278565( (2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(2-methoxypr...)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278613BDBM278613((2E)-3-(1-{[3-(2,6- Dichlorophenyl)-5-(3- methylox...)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278621BDBM278621((2E)-3-(3-Methyl-1-{[5-[1-(methylamino)cyclobutyl]...)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278559BDBM278559((2E)-3-(1-{[5-(2-Fluoropropan-2-yl)-3-(2,4,6-trich...)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278631BDBM278631((2E)-3-(1-{[5-(1-Cyanocyclobutyl)-3-(2,4,6-trichlo...)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278568BDBM278568( (2E)-3-(1-{[3-(2,6-Dichloro-3-fluorophenyl)-5-(pr...)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278577BDBM278577( (2E)-3-(1-{[3-(2-Bromo-6-chlorophenyl)-5-(tert-bu...)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278553BDBM278553( (2E)-[1-{[3-(2,4-Dichloro-6-fluorophenyl)-5-(1-me...)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278676BDBM278676( (2E)-3-(1-{[5-(Dimethylamino)-3-(2,4,6-trichlorop...)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278574BDBM278574( (2E)-3-(1-{[5-(2-Fluoropropan-2-yl)-3-(2,4,6-tric...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278575BDBM278575( (2E)-3-(1-{[5-(1-Methylcyclopropyl)-3-(2,4,6-tric...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278583BDBM278583( (2E)-3-(3-Fluoro-1-{[5-(2-fluoropropan-2-yl)-3-(2...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278585BDBM278585((2E)-3-(1-{[3-(2,4-Dichloro-6- fluorophenyl)-5-(2-...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278620BDBM278620((2E)-3-(1-{[5-[1- (Dimethylamino)cyclopropyl]- 3-(...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278549BDBM278549( (2E)-3-(1-{[3-(3,5-Dichloropyridin-2-yl)-5-(2-flu...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278567BDBM278567( (2E)-3-(1-{[5-(Propan-2-yl)-3-(2,4,6-trichlorophe...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278623BDBM278623((2E)-[1-({5-[2- (Methylamino)propan-2-yl]-3- (2,4,...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278552BDBM278552( (2E)-3-(1-{[3-(2,4-Dichloro-6-fluorophenyl)-5-(1-...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278593BDBM278593((2E)-3-(1-{[3-(4-Chloro-2,6- dimethylphenyl)-5-(2-...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278673BDBM278673( (2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(pyrrolidin-...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278604BDBM278604((2E)-3-(3-Chloro-1-{[5-(2- fluoropropan-2-yl)-3-(2...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278606BDBM278606((2E)-3-(1-{[3-(4-Bromo-2,6- dichlorophenyl)-5-(2- ...)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278622BDBM278622((2E)-3-[3-Methyl-1-({5-[2- (methylamino)propan-2-y...)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278601BDBM278601((2E)-3-(1-{[3-(2,4-Dichloro-5- fluorophenyl)-5-(2-...)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278554BDBM278554( (2E)-[1-{[3-(2,4-Dichloro-6-fluorophenyl)-5-(2-fl...)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278594BDBM278594((2E)-3-(1-{[3-(2,6-Dichloro-4- methylphenyl)-5-(2-...)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Daiichi Sankyo

US Patent
LigandChemical structure of BindingDB Monomer ID 278589BDBM278589((2E)-3-(1-{[5-(1,1- Difluoroethyl)-3-(2,4,6- trich...)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
US Patent

Displayed 1 to 50 (of 334 total ) | Next | Last >>
Jump to: