Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50005286
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035208(1-Pyridin-4-yl-1a,2,3,7b-tetrahydro-1H-cyclopropa[...)
Affinity DataIC50: 66nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035206(4-(5-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 69nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035209(4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...)
Affinity DataIC50: 185nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 265nMAssay Description:In vitro inhibition of rat ovarian microsomal Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035211(1-Pyridin-4-yl-1a,2,3,7b-tetrahydro-1H-cyclopropa[...)
Affinity DataIC50: 330nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035213(4-(6-Methoxy-1-methyl-1a,2,3,7b-tetrahydro-1H-cycl...)
Affinity DataIC50: 370nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035205(4-(5-Bromo-6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclo...)
Affinity DataIC50: 920nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035205(4-(5-Bromo-6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclo...)
Affinity DataIC50: 920nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035209(4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035212(4-(4-Methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 3.35E+3nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035210(4-(7-Bromo-4-methoxy-1a,2,3,7b-tetrahydro-1H-cyclo...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035207(1-(pyridin-4-yl)-1a,2,3,7b-tetrahydro-1H-cycloprop...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 6.20E+3nMAssay Description:In vitro inhibition of rat ovarian microsomal Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035208(1-Pyridin-4-yl-1a,2,3,7b-tetrahydro-1H-cyclopropa[...)
Affinity DataIC50: 7.00E+3nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibition of ACTH-stimulated corticosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibition of ACTH-stimulated corticosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035208(1-Pyridin-4-yl-1a,2,3,7b-tetrahydro-1H-cyclopropa[...)
Affinity DataIC50: 7.60E+4nMAssay Description:In vitro inhibition of ACTH-stimulated corticosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 8.00E+4nMAssay Description:In vitro inhibition of ACTH-stimulated corticosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 8.00E+4nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50: 9.50E+4nMAssay Description:In vitro inhibition of ACTH-stimulated corticosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed