Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 10214
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520619BDBM520619(US11147801, Compound 8 | 2-methyl-6-(2'-methyl-[1,...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520620BDBM520620(US11147801, Compound 12 | 5-(4-(2,5-dimethyl-1H-py...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520621BDBM520621(US11147801, Compound 19 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520622BDBM520622(US11147801, Compound 24 | 2-methyl-6-(2,3,5,6-tetr...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520617BDBM520617(US11147801, Compound 1 | 1-methyl-5-(2'-methyl-[1,...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520618BDBM520618(US11147801, Compound 2 | 1-methyl-5-(2'-methyl-[1,...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520623BDBM520623(US11147801, Compound 3 | 5-([1,1'-biphenyl]-4-yl)-...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520624BDBM520624(US11147801, Compound 4 | 6-([1,1'-biphenyl]-4-yl)-...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520625BDBM520625(US11147801, Compound 11 | 2-methyl-6-(2'-methyl-[1...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520626BDBM520626(US11147801, Compound 13 | 6-(4-(2,5-dimethyl-1H-py...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520627BDBM520627(US11147801, Compound 25 | 1-methyl-5-(2'-(morpholi...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520628BDBM520628(US11147801, Compound 29 | 1-methyl-5-(2'-((4-methy...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520629BDBM520629(US11147801, Compound 33 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520630BDBM520630(US11147801, Compound 34 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520631BDBM520631(US11147801, Compound 36 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520632BDBM520632(US11147801, Compound 38 | 2-methyl-6-(2,3,5,6-tetr...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520633BDBM520633(US11147801, Compound 39 | 2-methyl-6-(2,3,5,6-tetr...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520634BDBM520634(US11147801, Compound 40 | 5-(3'-((dimethylamino)me...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520635BDBM520635(US11147801, Compound 15 | 1-methyl-5-(3'-(morpholi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520636BDBM520636(US11147801, Compound 16 | 2-methyl-6-(3'-(morpholi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520637BDBM520637(US11147801, Compound 17 | 1-methyl-5-(3'-(pyrrolid...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520638BDBM520638(US11147801, Compound 20 | 1-methyl-6-(3'-(piperidi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520639BDBM520639(US11147801, Compound 26 | 2-methyl-6-(2'-(morpholi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520640BDBM520640(US11147801, Compound 27 | 1-methyl-5-(2'-(pyrrolid...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520641BDBM520641(US11147801, Compound 30 | 2-methyl-6-(2'-((4-methy...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520642BDBM520642(US11147801, Compound 31 | 1-methyl-5-(4'-(morpholi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520643BDBM520643(US11147801, Compound 32 | 5-(3'-acetamido-[1,1'-bi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520644BDBM520644(US11147801, Compound 35 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 520645BDBM520645(US11147801, Compound 37 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent