Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 11521
TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622567BDBM622567(US20230312587, Compound 275 | (7S)-4,7,8-trimethyl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622568BDBM622568(US20230312587, Compound 311 | (7S)-4,7,8-trimethyl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622569BDBM622569(US20230312587, Compound 335 | (7S)-4,7,8-trimethyl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622555BDBM622555(US20230312587, Compound 192 | (7S)-4,7,8-trimethyl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622556BDBM622556(US20230312587, Compound 221 | 2′-(((1-(4-flu...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622557BDBM622557(US20230312587, Compound 223 | 2′-(((1-(4-flu...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622558BDBM622558(US20230312587, Compound 224 | 2-(((1-(4-fluorobenz...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622551BDBM622551(US20230312587, Compound 116 | (7S)-2-(((1-(2,3-dih...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622552BDBM622552(US20230312587, Compound 136 | (7S)-4,7,8-trimethyl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622553BDBM622553(US20230312587, Compound 138 | (7S)-2-(((1-((3,5-di...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622554BDBM622554(US20230312587, Compound 160 | (7S)-4,7,8-trimethyl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622563BDBM622563(US20230312587, Compound 253 | (7S)-4,5,7,8-tetram...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622564BDBM622564(US20230312587, Compound 254 | (7S)-4,7,8-trimethyl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622565BDBM622565(US20230312587, Compound 267 | (S)-4,7,8-trimethyl-...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622566BDBM622566(US20230312587, Compound 268 | (S)-4,7,8-trimethyl-...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622559BDBM622559(US20230312587, Compound 229 | 5,7,7,8-tetramethyl-...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622560BDBM622560(US20230312587, Compound 234 | (7R)-5,7,8-triethyl-...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622561BDBM622561(US20230312587, Compound 246 | (7S)-4,7,8-trimethyl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622562BDBM622562(US20230312587, Compound 247 | (7S)-4,7,8-trimethy...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622539BDBM622539(US20230312587, Compound 30 | 5,8-diethyl-2-(((1-(4...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622540BDBM622540(US20230312587, Compound 32 | (R)-7-ethyl-2-(((1-(4...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622541BDBM622541(US20230312587, Compound 34 | (7S)-5,7,8-triethyl-2...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622542BDBM622542(US20230312587, Compound 44 | (7S)-2-(((1-(3,5-difl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622535BDBM622535(US20230312587, Compound 19 | (7S)-5,7-Diethyl-2-((...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622536BDBM622536(US20230312587, Compound 22 | (7S)-8-ethyl-2-(((1-(...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622537BDBM622537(US20230312587, Compound 23 | 5,8-dimethyl-7-propyl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622538BDBM622538(US20230312587, Compound 24 | 2-(((1-(4-fluorobenzy...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622547BDBM622547(US20230312587, Compound 51 | (7S)-5-ethyl-8-isopro...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622548BDBM622548(US20230312587, Compound 54 | (7S)-2-(((6-(4-fluoro...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622549BDBM622549(US20230312587, Compound 112 | (7S)-2-(((trans-1-(...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622550BDBM622550(US20230312587, Compound 113 | (7S)-2-(((1-(2-cyclo...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622543BDBM622543(US20230312587, Compound 46 | (7S)-2-(((1-(3,5-difl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622544BDBM622544(US20230312587, Compound 47 | (7S)-4,7,8-trimethyl-...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622545BDBM622545(US20230312587, Compound 48 | (7S)-2-(((1-(3,5-difl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622546BDBM622546(US20230312587, Compound 50 | (7S)-2-(((1-(3,5-difl...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622504BDBM622504(US20230312587, Compound 1)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622525BDBM622525(US20230312587, Compound 2)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622526BDBM622526(US20230312587, Compound 3)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622531BDBM622531(US20230312587, Compound 8)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622532BDBM622532(US20230312587, Compound 9)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622533BDBM622533(US20230312587, Compound 14 | (7S)-4,5,7,8-tetramet...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622534BDBM622534(US20230312587, Compound 15 | (7S)-7-Ethyl-5,8-dime...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622527BDBM622527(US20230312587, Compound 4)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622528BDBM622528(US20230312587, Compound 5)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622529BDBM622529(US20230312587, Compound 6)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 622530BDBM622530(US20230312587, Compound 7)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent