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Found 46 Enz. Inhib. hit(s) with all data for entry = 6421
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128119(US8796297, 25)
Affinity DataKi:  5.75nM ΔG°:  -43.7kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM50361016(CHEMBL501882 | US8796297, 13)
Affinity DataKi:  7.41nM ΔG°:  -43.1kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128117(US8796297, 23)
Affinity DataKi:  12.3nM ΔG°:  -42.0kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128103(US8796297, 6)
Affinity DataKi:  13.2nM ΔG°:  -41.8kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50361016(CHEMBL501882 | US8796297, 13)
Affinity DataKi:  13.8nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128120(US8796297, 2)
Affinity DataKi:  20nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128119(US8796297, 25)
Affinity DataKi:  24nM ΔG°:  -40.4kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128123(US8796297, 12)
Affinity DataKi:  24.5nM ΔG°:  -40.4kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128104(US8796297, 7)
Affinity DataKi:  28.2nM ΔG°:  -40.1kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128116(US8796297, 22)
Affinity DataKi:  33.1nM ΔG°:  -39.7kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128120(US8796297, 2)
Affinity DataKi:  53.7nM ΔG°:  -38.6kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128115(US8796297, 21)
Affinity DataKi:  55nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128114(US8796297, 20)
Affinity DataKi:  58.9nM ΔG°:  -38.4kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128103(US8796297, 6)
Affinity DataKi:  61.7nM ΔG°:  -38.3kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128117(US8796297, 23)
Affinity DataKi:  67.6nM ΔG°:  -38.0kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128123(US8796297, 12)
Affinity DataKi:  72.4nM ΔG°:  -37.9kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128104(US8796297, 7)
Affinity DataKi:  81.3nM ΔG°:  -37.6kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128116(US8796297, 22)
Affinity DataKi:  97.7nM ΔG°:  -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128118(US8796297, 24)
Affinity DataKi:  105nM ΔG°:  -37.0kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128110(US8796297, 16)
Affinity DataKi:  141nM ΔG°:  -36.3kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128113(US8796297, 19)
Affinity DataKi:  158nM ΔG°:  -36.1kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128115(US8796297, 21)
Affinity DataKi:  162nM ΔG°:  -36.0kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128112(US8796297, 18)
Affinity DataKi:  162nM ΔG°:  -36.0kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128106(US8796297, 10)
Affinity DataKi:  162nM ΔG°:  -36.0kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128121(US8796297, 4)
Affinity DataKi:  162nM ΔG°:  -36.0kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128113(US8796297, 19)
Affinity DataKi:  170nM ΔG°:  -35.9kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128106(US8796297, 10)
Affinity DataKi:  178nM ΔG°:  -35.8kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128105(US8796297, 8)
Affinity DataKi:  195nM ΔG°:  -35.6kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128102(US8796297, 3)
Affinity DataKi:  257nM ΔG°:  -35.0kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128114(US8796297, 20)
Affinity DataKi:  302nM ΔG°:  -34.6kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128102(US8796297, 3)
Affinity DataKi: >309nM ΔG°: >-34.5kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128107(US8796297, 11)
Affinity DataKi: >316nM ΔG°: >-34.5kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128122(US8796297, 5)
Affinity DataKi: >316nM ΔG°: >-34.5kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128105(US8796297, 8)
Affinity DataKi:  316nM ΔG°:  -34.5kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128118(US8796297, 24)
Affinity DataKi:  324nM ΔG°:  -34.4kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128121(US8796297, 4)
Affinity DataKi: >331nM ΔG°: >-34.4kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128109(US8796297, 15)
Affinity DataKi: >331nM ΔG°: >-34.4kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128122(US8796297, 5)
Affinity DataKi: >339nM ΔG°: >-34.3kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128111(US8796297, 17)
Affinity DataKi: >339nM ΔG°: >-34.3kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128107(US8796297, 11)
Affinity DataKi: >339nM ΔG°: >-34.3kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128109(US8796297, 15)
Affinity DataKi: >355nM ΔG°: >-34.2kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbvie

US Patent
LigandPNGBDBM128108(US8796297, 14)
Affinity DataKi: >355nM ΔG°: >-34.2kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128110(US8796297, 16)
Affinity DataKi: >363nM ΔG°: >-34.2kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128111(US8796297, 17)
Affinity DataKi: >363nM ΔG°: >-34.2kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128112(US8796297, 18)
Affinity DataKi: >363nM ΔG°: >-34.2kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM128108(US8796297, 14)
Affinity DataKi: >380nM ΔG°: >-34.1kJ/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent