Compile Data Set for Download or QSAR
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Found 126 of affinity data for UniProtKB/TrEMBL: P00807
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM39816(Acylglycineboronic acid, 15)
Affinity DataKi:  390nMpH: 7.0Assay Description:Enzyme inhibition assay using AmpC or TEM-1 from escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM39856(Amide and sulfonamide derivatives, 41)
Affinity DataKi:  2.00E+3nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM39849(Amide and sulfonamide derivatives, 33)
Affinity DataKi:  3.20E+3nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50115621((2-(thiophen-2-yl)acetamido)methylboronic acid | A...)
Affinity DataKi:  6.50E+3nMpH: 7.0Assay Description:Enzyme inhibition assay using AmpC or TEM-1 from escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50115620(3-(2-Chloro-phenyl)-5-methyl-2,3-dihydro-isoxazole...)
Affinity DataKi:  6.80E+3nMpH: 7.0Assay Description:Enzyme inhibition assay using AmpC or TEM-1 from escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM39809(Acylglycineboronic acid, 6)
Affinity DataKi:  1.38E+4nMpH: 7.0Assay Description:Enzyme inhibition assay using AmpC or TEM-1 from escherichia coli.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM39808(Acylglycineboronic acid, 3)
Affinity DataKi:  3.80E+4nMpH: 7.0Assay Description:Enzyme inhibition assay using AmpC or TEM-1 from escherichia coli.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50202233(Acylglycineboronic acid, 5 | CHEMBL227673 | acetam...)
Affinity DataKi:  1.62E+5nMpH: 7.0Assay Description:Enzyme inhibition assay using AmpC or TEM-1 from escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM39817(Boric acid | Boronic Acid)
Affinity DataKi:  1.50E+6nMpH: 7.0Assay Description:Enzyme inhibition assay using AmpC or TEM-1 from escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM39818(Methylboronic Acid)
Affinity DataKi:  2.50E+6nMpH: 7.0Assay Description:Enzyme inhibition assay using AmpC or TEM-1 from escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079694(CHEMBL294608 | Sodium; (2S,3R)-3-methyl-4,4,7-trio...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against serine Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079695(CHEMBL294203 | sodium (2S,3R,5R,6Z)-3-[(acetyloxy)...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against serine Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079686(CHEMBL292093 | disodium (2S,3R,5R,6Z)-3-methyl-6-(...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against serine beta-lactamase, PC1 (class A) derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50021959(CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...)
Affinity DataIC50:  25.1nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails DrugBank

TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079689(CHEMBL303053 | Sodium; (2S,3R)-3-[2-(3,4-dihydroxy...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against serine Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50033680(CHEMBL268919 | Sodium; (R)-3-acetoxymethyl-7-[1-te...)
Affinity DataIC50:  30nMAssay Description:The compound was evaluated for inhibition against Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079694(CHEMBL294608 | Sodium; (2S,3R)-3-methyl-4,4,7-trio...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against serine Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212641(Brobactam)
Affinity DataIC50:  46.4nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079689(CHEMBL303053 | Sodium; (2S,3R)-3-[2-(3,4-dihydroxy...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against serine Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079695(CHEMBL294203 | sodium (2S,3R,5R,6Z)-3-[(acetyloxy)...)
Affinity DataIC50:  62nMAssay Description:Inhibitory activity against serine Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212643(CHEMBL308516)
Affinity DataIC50:  71.8nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50021959(CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against Penicillinase from Staphylococcus aureus TH-14 using piperacillin (40 uM) as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50088831(CHEMBL353613 | Sodium; 3-((E)-2-carbamoyl-vinyl)-5...)
Affinity DataIC50:  100nMAssay Description:Inhibition of class A beta-lactamase derived from Staphylococcus aureus strain PC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212634(CHEMBL309009)
Affinity DataIC50:  104nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079684(CHEMBL305361 | disodium (2S,3R,5R,6Z)-3-({[(3,4-di...)
Affinity DataIC50:  105nMAssay Description:Inhibitory activity against serine Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212642(CHEMBL70269)
Affinity DataIC50:  116nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212636(CHEMBL310221)
Affinity DataIC50:  125nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50021959(CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Staphylococcus aureus Russell beta-lactamase assessed as inhibition of nitrocefin hydrolysis pre-incubated for 5 mins by microtiter pla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  166nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079685(CHEMBL61762 | disodium (2S,3R,5R,6Z)-3-[(acetyloxy...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against serine Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212638(CHEMBL302512)
Affinity DataIC50:  181nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079682(CHEMBL64793 | disodium (2S,3R,5R,6Z)-3-{[(chloroac...)
Affinity DataIC50:  196nMAssay Description:Inhibitory activity against serine Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50088825(CHEMBL353422 | Sodium; 3-((E)-2-nitro-vinyl)-5,5,8...)
Affinity DataIC50:  200nMAssay Description:Inhibition of class A beta-lactamase derived from Staphylococcus aureus strain PC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079692(CHEMBL292506 | Disodium; (2S,3R)-6-[1-carboxy-meth...)
Affinity DataIC50:  233nMAssay Description:Inhibitory activity against serine beta-lactamase, PC1 (class A) derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50076680(CHEMBL6461 | Ro-48-1220 | Sodium; (2S,3R,5R)-3-((Z...)
Affinity DataIC50:  250nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Staphylococcus aureus PCIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50021956(CHEMBL285387 | Sodium; 3-methyl-2,2,6-trioxo-3-[1,...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity against Penicillinase from Staphylococcus aureus TH-14 using piperacillin (40 uM) as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212639(CHEMBL302241)
Affinity DataIC50:  289nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)
Affinity DataIC50:  290nMAssay Description:The compound was evaluated for inhibition against Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50421413(CL-307579 | TAZOBACTAM SODIUM | Tazocillin)
Affinity DataIC50:  297nMAssay Description:Inhibitory activity against serine Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50088834(CHEMBL169392 | Sodium; 3-((E)-2-methoxycarbonyl-vi...)
Affinity DataIC50:  300nMAssay Description:Inhibition of class A beta-lactamase derived from Staphylococcus aureus strain PC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079690(CHEMBL304709 | sodium (2S,3R,5R,6Z)-3-[(acetyloxy)...)
Affinity DataIC50:  310nMAssay Description:Inhibitory activity against serine Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212645(CHEMBL305908)
Affinity DataIC50:  342nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079684(CHEMBL305361 | disodium (2S,3R,5R,6Z)-3-({[(3,4-di...)
Affinity DataIC50:  370nMAssay Description:Inhibitory activity against serine Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079694(CHEMBL294608 | Sodium; (2S,3R)-3-methyl-4,4,7-trio...)
Affinity DataIC50:  390nMAssay Description:Inhibitory activity against serine Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212646(CHEMBL72972)
Affinity DataIC50:  419nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212640(CHEMBL423309)
Affinity DataIC50:  461nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  500nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Staphylococcus aureus PCIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212644(CHEMBL73450)
Affinity DataIC50:  509nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50079686(CHEMBL292093 | disodium (2S,3R,5R,6Z)-3-methyl-6-(...)
Affinity DataIC50:  540nMAssay Description:Inhibitory activity against serine beta-lactamase, PC1 (class A) derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Northwestern University

LigandPNGBDBM50212637(CHEMBL72046)
Affinity DataIC50:  570nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
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