BDBM50152850 1-HEXYLDECANOIC ACID::CHEMBL82293::Hexadecanoic acid::Hexadecanoic acid anion::Palmitic acid (PA)
SMILES CCCCCCCCCCCCCCCC(O)=O
InChI Key InChIKey=IPCSVZSSVZVIGE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 23 hits for monomerid = 50152850
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 336nMAssay Description:Displacement of 1,8-ANS from aFABP by fluorescence based-assayMore data for this Ligand-Target Pair
Affinity DataKi: 670nM ΔG°: -8.56kcal/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
Affinity DataKi: 690nM ΔG°: -8.54kcal/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
Affinity DataKi: 802nMAssay Description:Displacement of 1,8-ANS from eFABP by fluorescence based-assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.06E+3nM ΔG°: -7.64kcal/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibitory concentration against intestinal fatty acid binding protein(I-FABP)More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibitory concentration against epithelial fatty acid binding protein(E-FABP)More data for this Ligand-Target Pair
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP)More data for this Ligand-Target Pair
Affinity DataKd: 802nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
University of Oslo
Curated by ChEMBL
University of Oslo
Curated by ChEMBL
Affinity DataEC50: 3.50E+4nMAssay Description:Agonist activity at recombinant human PPARalpha LBD (168 to 468 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by lucif...More data for this Ligand-Target Pair
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKd: 8.30E+4nMAssay Description:Binding affinity against Adipocyte lipid binding proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of TLR2 agonist Pam3Cys-Ser-(Lys)4-OH-mediated IL8 secretion in THP1 cellsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
National Research Council (CNR)
Curated by ChEMBL
National Research Council (CNR)
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
National Research Council (CNR)
Curated by ChEMBL
National Research Council (CNR)
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured at 1...More data for this Ligand-Target Pair
Affinity DataKd: 3.72E+3nMAssay Description:Binding affinity against Fatty acid-binding proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
University of Oslo
Curated by ChEMBL
University of Oslo
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 mins by photometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibitory concentration against heart and muscle fatty acid binding protein(H-FABP)More data for this Ligand-Target Pair