126 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 1.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
3,4-Diaza-bicyclo[4.1.0]hept-4-en-2-one phenoxypropylamine analogs of irdabisant (CEP-26401) as potent histamine-3 receptor inverse agonists with robust wake-promoting activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Teva Global R & D.
Studies on molecular properties prediction and histamine H3 receptor affinities of novel ligands with uracil-based motifs.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
University of Catania
Benzylpiperidine variations on histamine H3 receptor ligands for improved drug-likeness.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Johann Wolfgang Goethe University
Discovery of (1R,6S)-5-[4-(1-cyclobutyl-piperidin-4-yloxy)-phenyl]-3,4-diaza-bicyclo[4.1.0]hept-4-en-2-one (R,S-4a): histamine H(3) receptor inverse agonist demonstrating potent cognitive enhancing and wake promoting activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Teva Pharmaceutical Global R & D
Identification of clinical candidates from the benzazepine class of histamine H3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Glaxosmithkline
The discovery of the benzazepine class of histamine H3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Glaxosmithkline
Identification and profiling of 3,5-dimethyl-isoxazole-4-carboxylic acid [2-methyl-4-((2S,3'S)-2-methyl-[1,3']bipyrrolidinyl-1'-yl)phenyl] amide as histamine H(3) receptor antagonist for the treatment of depression.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Sanofi Us
Synthesis, characterization, and biological assessment of the four stereoisomers of the H(3) receptor antagonist 5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl)phenyl]benzamide.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Sanofi Us
Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part II).![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Sanofi Us
Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part I).![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Sanofi Us
Dibasic biphenyl H3 receptor antagonists: Steric tolerance for a lipophilic side chain.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Universit£
Rigidified 2-aminopyrimidines as histamine H4 receptor antagonists: effects of substitution about the rigidifying ring.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Johnson & Johnson Pharmaceutical Research & Development
Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Universit£
Synthesis and SAR of aminoalkoxy-biaryl-4-carboxamides: novel and selective histamine H3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 2: binding preference for D-amino acids motifs.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
Diphenylmethyl ethers: synthesis and histamine H3-receptor antagonist in vitro and in vivo activity![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Radiofluorinated histamine H3 receptor antagonist as a potential probe for in vivo PET imaging: radiosynthesis and pharmacological evaluation.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Eth Zurich (Swiss Federal Institute of Technology)
Discovery of two clinical histamine H(3) receptor antagonists: trans-N-ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) and trans-3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]-N-(2-methylpropyl)cyclobutanecarboxamide (PF-03654764).![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Pfizer
Synthesis and evaluation of 4- and 5-pyridazin-3-one phenoxypropylamine analogues as histamine-3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
Substituted phenoxypropyl-(R)-2-methylpyrrolidine aminomethyl ketones as histamine-3 receptor inverse agonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
Synthesis of constrained benzocinnolinone analogues of CEP-26401 (irdabisant) as potent, selective histamine H3 receptor inverse agonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
2-(Pyrrolidin-1-yl)ethyl-3,4-dihydroisoquinolin-1(2H)-one derivatives as potent and selective histamine-3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Pfizer
Radiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofuran chemotype.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
National Institute of Mental Health
Synthesis and evaluation of a new series of 1'-cyclobutyl-6-(4-piperidyloxy)spiro[benzopyran-2,4'-piperidine] derivatives as high affinity and selective histamine-3 receptor (H3R) antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
Synthesis and structure-activity relationships of 4,5-fused pyridazinones as histamine H3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
Identification of pyridazin-3-one derivatives as potent, selective histamine H3 receptor inverse agonists with robust wake activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
Discovery and characterization of 6-{4-[3-(R)-2-methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, irdabisant): a potent, selective histamine H3 receptor inverse agonist.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity rela![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Pfizer
Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: identification of candidates for clinical development.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Johnson & Johnson Pharmaceutical Research & Development
5-hydroxyindole-2-carboxylic acid amides: novel histamine-3 receptor inverse agonists for the treatment of obesity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
F. Hoffmann-La Roche
Diether derivatives of homo- or substituted piperidines as non-imidazole histamine H3 receptor ligands.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Jagiellonian University Medical College
A new family of H3 receptor antagonists based on the natural product Conessine.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Arena Pharmaceuticals
In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Universit£
4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H3 receptor antagonists potently enhance cognition and attention.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
Influence of bulky substituents on histamine h(3) receptor agonist/antagonist properties.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie Universit£T Berlin
Development of a pharmacophore model for histamine H3 receptor antagonists, using the newly developed molecular modeling program SLATE.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
De Novo Pharmaceuticals
Novel histamine H(3)-receptor antagonists with carbonyl-substituted 4-(3-(phenoxy)propyl)-1H-imidazole structures like ciproxifan and related compounds.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie Universit£T Berlin
Diastereoselective synthesis of trans-2-(1-triphenylmethyl-1H-imidazol-4-yl)cyclopropanecarboxylic acids: key intermediates for the preparation of potent and chiral histamine H3 receptor agents![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Novel morpholine ketone analogs as potent histamine H3 receptor inverse agonists with wake activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
4-phenoxypiperidine pyridazin-3-one histamine H(3) receptor inverse agonists demonstrating potent and robust wake promoting activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
Synthesis and structure-activity relationship of 5-pyridazin-3-one phenoxypiperidines as potent, selective histamine H(3) receptor inverse agonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: discovery of (R)-1-(2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916).![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Arena Pharmaceuticals
Ligand based design of novel histamine H4 receptor antagonists; fragment optimization and analysis of binding kinetics.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Griffin Discoveries
Synthesis and evaluation of 4-alkoxy-[1'-cyclobutyl-spiro(3,4-dihydrobenzopyran-2,4'-piperidine)] analogues as histamine-3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
4,5-dihydropyridazin-3-one derivatives as histamine H3 receptor inverse agonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
Synthesis and evaluation of pyridone-phenoxypropyl-R-2-methylpyrrolidine analogues as histamine H3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
Synthesis and evaluation of pyridazinone-phenethylamine derivatives as selective and orally bioavailable histamine H3 receptor antagonists with robust wake-promoting activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Cephalon
Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Johnson & Johnson Pharmaceutical Research and Development
Diaryldiamines with dual inhibition of the histamine H(3) receptor and the norepinephrine transporter and the efficacy of 4-(3-(methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in pain.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
Discovery of potent and selective histamine H3 receptor inverse agonists based on the 3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one scaffold.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
F. Hoffmann-La Roche
Discovery of substituted benzyl tetrazoles as histamine H3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Evotec (Uk)
In vitro studies on a class of quinoline containing histamine H3 antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Johnson & Johnson Pharmaceutical Research & Development
Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Jagiellonian University Medical College
Benzimidazole- and indole-substituted 1,3'-bipyrrolidine benzamides as histamine H3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Wyeth Research
Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Arena Pharmaceuticals
Synthesis, structure-activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H(3) receptor inverse agonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Tsukuba Research Institute
Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Tsukuba Research Institute
Design of a new histamine H3 receptor antagonist chemotype: (3aR,6aR)-5-alkyl-1-aryl-octahydropyrrolo[3,4-b]pyrroles, synthesis, and structure-activity relationships.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
2-Aryloxymethylmorpholine histamine H(3) antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Johnson & Johnson Pharmaceutical Research & Development
Imetit and N-methyl derivatives. The transition from potent agonist to antagonist at histamine H3 receptors.1![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Novel imidazole-based histamine H3 antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Johnson & Johnson Pharmaceutical Research & Development
Synthesis and evaluation of structurally constrained quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Tsukuba Research Institute
Total synthesis and biological evaluation of the marine bromopyrrole alkaloid dispyrin: elucidation of discrete molecular targets with therapeutic potential.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Vanderbilt University
Synthesis, structure-activity relationships, and biological profiles of a quinazolinone class of histamine H3 receptor inverse agonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Tsukuba Research Institute
Novel H3 receptor antagonists with improved pharmacokinetic profiles.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Arena Pharmaceuticals
Diamine derivatives containing imidazolidinylidene propanedinitrile as a new class of histamine H3 receptor antagonists. Part I.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Kyowa Hakko Kogyo
Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
A new class of histamine H3 receptor antagonists derived from ligand based design.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
F. Hoffmann-La Roche
4-[6-(2-Aminoethyl)naphthalen-2-yl]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
Aplysamine-1 and related analogs as histamine H3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Johnson & Johnson Pharmaceutical Research and Development
Synthesis and SAR of 5-amino- and 5-(aminomethyl)benzofuran histamine H3 receptor antagonists with improved potency.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
University College London
4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie UniversitäT Berlin
A new class of potent non-imidazole H(3) antagonists: 2-aminoethylbenzofurans.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 3: 5-Substituted 3-phenyl-1,2,4-oxadiazoles as potent antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
A new class of histamine H(3)-receptor antagonists: synthesis and structure-activity relationships of 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolines.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Abbott Laboratories
Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Hokkaido University
Structural modifications in the distal, regulatory region of histamine H![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Jagiellonian University Medical College
Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Soochow University
Novel human histamine H(3) receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Johnson and Johnson Pharmaceutical Research and Development
Different antagonist binding properties of human and rat histamine H3 receptors.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie UniversitäT Berlin
Analogues and derivatives of ciproxifan, a novel prototype for generating potent histamine H3-receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie UniversitäT Berlin
New histamine H(3)-receptor ligands of the proxifan series: imoproxifan and other selective antagonists with high oral in vivo potency.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie UniversitäT Berlin
Novel partial agonists for the histamine H(3) receptor with high in vitro and in vivo activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie UniversitäT Berlin
Design, synthesis, and structure-activity relationships of acetylene-based histamine H3 receptor antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Gliatech
Development of chiral N-alkylcarbamates as new leads for potent and selective H3-receptor antagonists: synthesis, capillary electrophoresis, and in vitro and oral in vivo activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie UniversitäT Berlin
Discovery and Development of N-[4-(1-Cyclobutylpiperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide Dihydrochloride (SUVN-G3031): A Novel, Potent, Selective, and Orally Active Histamine H![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Suven Life Sciences
General construction pattern of histamine H3-receptor antagonists: change of a paradigm.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie UniversitäT Berlin
New acetylene based histamine H3 receptor antagonists derived from the marine natural product verongamine.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Gliatech
4-Alkynylphenyl imidazolylpropyl ethers as selective histamine H3-receptor antagonists with high oral central nervous system activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie UniversitäT Berlin
Synthesis and evaluation of histamine H![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Jiangsu Marine Resources Development Research Institute
A novel series of (phenoxyalkyl)imidazoles as potent H3-receptor histamine antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
University College London
Novel carbamates as potent histamine H3 receptor antagonists with high in vitro and oral in vivo activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie UniversitäT Berlin
[125I]iodoproxyfan and related compounds: a reversible radioligand and novel classes of antagonists with high affinity and selectivity for the histamine H3 receptor.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Freie UniversitäT Berlin
Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Solvay Duphar
Design of potent non-thiourea H3-receptor histamine antagonists.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
University College London
Dibasic non-imidazole histamine H3 receptor antagonists with a rigid biphenyl scaffold.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Universit£
Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
University of Kuopio
Characterization of the binding site of the histamine H3 receptor. 1. Various approaches to the synthesis of 2-(1H-imidazol-4-yl)cyclopropylamine and histaminergic activity of (1R,2R)- and (1S,2S)-2-(1H-imidazol-4-yl)-cyclopropylamine.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Vrije Universiteit
Synthesis and Biological Evaluation of Fused Tricyclic Heterocycle Piperazine (Piperidine) Derivatives As Potential Multireceptor Atypical Antipsychotics.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Huazhong University of Science and Technology
Design, synthesis, and biological evaluation of novel oxadiazole- and thiazole-based histamine H![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Heinrich Heine University D£Sseldorf
Synthesis and biological activity of novel tert-amylphenoxyalkyl (homo)piperidine derivatives as histamine H![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Jagiellonian University Medical College
Novel naphthyloxy derivatives - Potent histamine H![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Jagiellonian University Medical College
Histamine H3 ligands: just pharmacological tools or potential therapeutic agents?![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Vrije Universiteit
Identification and pharmacological characterization of a series of new 1H-4-substituted-imidazoyl histamine H3 receptor ligands.![BDB](/images/logo_bindingdb.png)
![BDB](/images/logo_bindingdb.png)
Gliatech
Stable expression of human H1-histamine-receptor cDNA in Chinese hamster ovary cells. Pharmacological characterisation of the protein, tissue distribution of messenger RNA and chromosomal localisation of the gene.![BDB](/images/logo_bindingdb.png)
![BDB](/images/logo_bindingdb.png)
UniversitÉ