BDB TargetNames

Target Names are taken from UniProtKB. To view the associated UniProt page, click on the UniProt ID. When we have data for a given Target in multiple species or for mutants of a given Target, we provide a header row (upper case, bold font) with all of the data followed by a separate for each species or variant of the Target.

Target Name
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Target Name

Organism

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D(1) dopamine receptor P35406

Goldfish

Ki: 9 EC50: 39

D(1A) DOPAMINE RECEPTOR O77680 P14416 P18901 P19020 P20288 P21728 P21917 P21918 P25115 P30728 P30729 P35462 P50130 P51436 P61168 P61169 Q61616 Q8BLD9 Q95136

Ki: 4183 IC50: 1499 Kd: 44 EC50: 781

D(1A) dopamine receptor P21728

Human

Ki: 2091 IC50: 365 Kd: 37 EC50: 740

D(1A) dopamine receptor Q61616

Mouse

Ki: 54 IC50: 6 EC50: 3

D(1A) dopamine receptor P18901

Rat

Ki: 1158 IC50: 402 Kd: 4 EC50: 37

D(1A) dopamine receptor Q95136

Bovine

Ki: 431 IC50: 59 Kd: 2

D(1A) dopamine receptor O77680

Rhesus macaque

Ki: 2

D(1A) dopamine receptor P50130

Pig

Ki: 306

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P14416 P21728 P21917 P21918 P35462

Human

Ki: 15 IC50: 8 EC50: 1

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P18901 P19020 P25115 P30729 P61169

Rat

Ki: 117 IC50: 523 Kd: 1

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P30728 P51436 P61168 Q61616 Q8BLD9

Mouse

IC50: 1

D(1A)/D(2) dopamine receptor P20288 Q95136

Bovine

Ki: 9 IC50: 135

D(1B) DOPAMINE RECEPTOR P14416 P18901 P19020 P21728 P21917 P21918 P25115 P30728 P30729 P35462 P51436 P61168 P61169 Q61616 Q8BLD9 Q95137

Ki: 854 IC50: 548 Kd: 5 EC50: 137

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P14416 P21728 P21917 P21918 P35462

Human

Ki: 15 IC50: 8 EC50: 1

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P18901 P19020 P25115 P30729 P61169

Rat

Ki: 117 IC50: 523 Kd: 1

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P30728 P51436 P61168 Q61616 Q8BLD9

Mouse

IC50: 1

D(1B) dopamine receptor P21918

Human

Ki: 659 IC50: 16 Kd: 4 EC50: 134

D(1B) dopamine receptor Q8BLD9

Mouse

Ki: 2 EC50: 2

D(1B) dopamine receptor P25115

Rat

Ki: 59

D(1B) dopamine receptor Q95137

Bovine

Ki: 1

D(1B) dopamine receptor P21918 P25115

Rat

Ki: 1

D(2) DOPAMINE RECEPTOR A0A1U7QAF5 A0A1V4J7Y5 F1SM69 G1T1Q0 P14416 P18901 P19020 P20288 P21728 P21917 P21918 P25115 P30728 P30729 P35462 P41594 P51436 P52702 P61168 P61169 Q61616 Q8BLD9 Q95136 Q9GJU1

Ki: 18758 IC50: 4735 Kd: 278 EC50: 1752

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P14416 P21728 P21917 P21918 P35462

Human

Ki: 15 IC50: 8 EC50: 1

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P18901 P19020 P25115 P30729 P61169

Rat

Ki: 117 IC50: 523 Kd: 1

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P30728 P51436 P61168 Q61616 Q8BLD9

Mouse

IC50: 1

D(1A)/D(2) dopamine receptor P20288 Q95136

Bovine

Ki: 9 IC50: 135

D(2) dopamine receptor P14416

Human

Ki: 167 IC50: 2

D(2) dopamine receptor P61169

Rat

Ki: 4491 IC50: 2273 Kd: 99 EC50: 111

D(2) dopamine receptor P14416

Human

Ki: 13427 IC50: 1433 Kd: 175 EC50: 1635

D(2) dopamine receptor P61168

Mouse

Ki: 54 IC50: 159

D(2) dopamine receptor Q9GJU1

Dog

Ki: 7 IC50: 1

D(2) dopamine receptor P20288

Bovine

Ki: 386 IC50: 197 Kd: 3

D(2) dopamine receptor A0A1U7QAF5

Golden hamster

Ki: 1

D(2) dopamine receptor F1SM69

Pig

Ki: 28

D(2) dopamine receptor A0A1V4J7Y5

pigeon

Ki: 7

D(2) dopamine receptor G1T1Q0

Rabbit

Ki: 21

D(2) dopamine receptor P52702

Green monkey

Ki: 26

D(2) dopamine receptor P14416 P61169

Rat

Ki: 2

D(2) dopamine receptor/Metabotropic glutamate receptor 5 P14416 P41594

Human

IC50: 3 EC50: 5

D(3) DOPAMINE RECEPTOR A0A1V4J3K6 A0A3Q0CXS4 F1N454 P14416 P18901 P19020 P21728 P21917 P21918 P25115 P30728 P30729 P35462 P51436 P52703 P61168 P61169 Q61616 Q8BLD9

Ki: 8793 IC50: 974 Kd: 24 EC50: 745

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P14416 P21728 P21917 P21918 P35462

Human

Ki: 15 IC50: 8 EC50: 1

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P18901 P19020 P25115 P30729 P61169

Rat

Ki: 117 IC50: 523 Kd: 1

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P30728 P51436 P61168 Q61616 Q8BLD9

Mouse

IC50: 1

D(3) dopamine receptor P35462

Human

Ki: 6645 IC50: 323 Kd: 3 EC50: 551

D(3) dopamine receptor P19020

Rat

Ki: 1127 IC50: 77 Kd: 6 EC50: 8

D(3) dopamine receptor P30728

Mouse

Ki: 6

D(3) dopamine receptor F1N454

Bovine

Ki: 4

D(3) dopamine receptor A0A3Q0CXS4

Chinese hamster

Ki: 1

D(3) dopamine receptor A0A1V4J3K6

pigeon

Ki: 6

D(3) dopamine receptor P35462

Human

Ki: 860 IC50: 42 Kd: 14 EC50: 185

D(3) dopamine receptor P52703

Green monkey

Ki: 12

D(4) DOPAMINE RECEPTOR P14416 P18901 P19020 P21728 P21917 P21918 P25115 P30728 P30729 P35462 P51436 P61168 P61169 Q61616 Q8BLD9

Ki: 3958 IC50: 969 Kd: 11 EC50: 419

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P14416 P21728 P21917 P21918 P35462

Human

Ki: 15 IC50: 8 EC50: 1

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P18901 P19020 P25115 P30729 P61169

Rat

Ki: 117 IC50: 523 Kd: 1

D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor P30728 P51436 P61168 Q61616 Q8BLD9

Mouse

IC50: 1

D(4) dopamine receptor P21917

Human

Ki: 3502 IC50: 433 Kd: 10 EC50: 403

D(4) dopamine receptor P51436

Mouse

Ki: 19

D(4) dopamine receptor P30729

Rat

Ki: 305 IC50: 1 EC50: 15

D(4) dopamine receptor [281-332] P21917

Human

IC50: 3

D-3-PHOSPHOGLYCERATE DEHYDROGENASE O43175

Human

Ki: 5 IC50: 910 Kd: 34 EC50: 2

D-3-phosphoglycerate dehydrogenase O43175

Human

Ki: 5 IC50: 908 Kd: 34 EC50: 2

D-3-phosphoglycerate dehydrogenase [3-314] O43175

Human

IC50: 2

D-ALANINE--D-ALANINE LIGASE Q1CTD3 Q47758

Ki: 2 IC50: 25 Kd: 1

D-alanine--D-alanine ligase Q1CTD3

Helicobacter pylori (strain HPAG1)

Ki: 2 IC50: 2 Kd: 1

D-alanine--D-alanine ligase Q47758

Enterococcus faecalis (strain ATCC 700802 / V583)

IC50: 23

D-alanine--D-alanine ligase B P07862

Escherichia coli (strain K12)

IC50: 3

D-ALANINE--D-ALANYL CARRIER PROTEIN LIGASE P59591 Q3XZT7 Q830N0

IC50: 189

D-alanine--D-alanyl carrier protein ligase Q830N0

Enterococcus faecalis (strain ATCC 700802 / V583)

IC50: 63

D-alanine--D-alanyl carrier protein ligase Q3XZT7

Enterococcus faecium E1679

IC50: 63

D-alanine--D-alanyl carrier protein ligase P59591

Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)

IC50: 63

D-alanyl-D-alanine carboxypeptidase P39045

Actinomadura sp. (strain R39)

Ki: 6 IC50: 26

D-alanyl-D-alanine carboxypeptidase DacA P08750

Bacillus subtilis (strain 168)

Kon: 2

D-alanyl-D-alanine dipeptidase Q06241

Enterococcus faecium

Ki: 6 IC50: 6

D-AMINO-ACID OXIDASE O35078 P00371 P14920 P18894 Q95XG9

Ki: 15 IC50: 1200 Kd: 57 EC50: 74

D-amino-acid oxidase P00371

Pig

Ki: 2 IC50: 123 Kd: 13

D-amino-acid oxidase P14920

Human

Ki: 13 IC50: 1014 Kd: 44 EC50: 39

D-amino-acid oxidase O35078

Rat

IC50: 43

D-amino-acid oxidase P18894

Mouse

IC50: 20 EC50: 33

D-amino-acid oxidase Q95XG9

Caenorhabditis elegans

EC50: 2

D-ASPARTATE OXIDASE D3ZDM7 P31228 Q922Z0 Q99489

Ki: 9 IC50: 86

D-aspartate oxidase Q99489

Human

Ki: 3 IC50: 80

D-aspartate oxidase P31228

Bovine

IC50: 6

D-aspartate oxidase Q922Z0

Mouse

Ki: 3

RCG38204, isoform CRA_d D3ZDM7

Rat

Ki: 3

D-aspartate oxidase 1 O45307

Caenorhabditis elegans

EC50: 2

D-aspartate oxidase 2 Q19564

Caenorhabditis elegans

EC50: 2

D-aspartate oxidase 3 O01739

Caenorhabditis elegans

EC50: 2

D-beta-D-heptose 7-phosphate kinase B4EB35

Burkholderia cepacia (strain J2315 / LMG 16656) (Burkholderiacenocepacia (strain J2315))

IC50: 2

DCN1-LIKE PROTEIN 1 P61081 Q96GG9

Human

Ki: 36 IC50: 1391 Kd: 15 EC50: 11

DCN1-like protein 1 Q96GG9

Human

Ki: 36 IC50: 701 Kd: 15 EC50: 11

DCN1-like protein 1/NEDD8-conjugating enzyme Ubc12 P61081 Q96GG9

Human

IC50: 690

DCN1-like protein 2 Q6PH85

Human

Ki: 4

DCN1-like protein 3 Q8IWE4

Human

Ki: 4

DCN1-like protein 4 Q92564

Human

Ki: 4

DCN1-like protein 5 Q9BTE7

Human

Ki: 4

dCTP deaminase Q9PN07

Campylobacter jejuni subsp. jejuni

Ki: 11

dCTP pyrophosphatase 1 Q9H773

Human

Ki: 5 IC50: 194

DDB1- and CUL4-associated factor 1 Q9Y4B6

Human

Kd: 28 EC50: 1

DDB1- AND CUL4-ASSOCIATED FACTOR 15 Q14498 Q66K64

Human

Kd: 16 EC50: 178

DDB1- and CUL4-associated factor 15 Q66K64

Human

Kd: 16 EC50: 45

RNA-binding protein 39 [150-331]/DDB1- and CUL4-associated factor 15 Q14498 Q66K64

Human

EC50: 133

Death-associated protein kinase 1 P53355

Human

Ki: 3 IC50: 73 Kd: 137 EC50: 1

Death-associated protein kinase 2 Q9UIK4

Human

IC50: 18 Kd: 133

Death-associated protein kinase 3 O43293

Human

Ki: 7 IC50: 52 Kd: 174

Decaprenyl diphosphate synthase P9WFF6

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

IC50: 94

DECAPRENYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE A0R211 P9WMW5

IC50: 7

Decaprenyl-phosphate N-acetylglucosaminephosphotransferase P9WMW5

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 6

Decaprenyl-phosphate N-acetylglucosaminephosphotransferase A0R211

Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacteriumsmegmatis)

IC50: 1

DECAPRENYLPHOSPHORYL-BETA-D-RIBOSE OXIDASE A0R607 P9WJF1

IC50: 148

Decaprenylphosphoryl-beta-D-ribose oxidase A0R607

Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacteriumsmegmatis)

IC50: 1

Decaprenylphosphoryl-beta-D-ribose oxidase P9WJF1

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 147

Dedicator of cytokinesis protein 2 Q92608

Human

IC50: 8

DEDICATOR OF CYTOKINESIS PROTEIN 5 B2RY04 Q9H7D0

IC50: 12

Dedicator of cytokinesis protein 5 B2RY04

Mouse

IC50: 2

Dedicator of cytokinesis protein 5 Q9H7D0

Human

IC50: 10

Dehaloperoxidase B Q9NAV7

Amphitrite ornata

Kd: 3

DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 9 Q8VD48 Q9BPW9

IC50: 24

Dehydrogenase/reductase SDR family member 9 Q9BPW9

Human

IC50: 3

Dehydrogenase/reductase SDR family member 9 Q8VD48

Rat

IC50: 21

Delta and Notch-like epidermal growth factor-related receptor Q8NFT8

Human

IC50: 1

Delta carbonic anhydrase Q5U9J1

Thalassiosira weissflogii

Ki: 40

Delta(14)-sterol reductase B4FS76

Maize

IC50: 10

Delta(24)-sterol reductase Q15392

Human

IC50: 13

Delta(7)-sterol 5(6)-desaturase O93875

Yeast

IC50: 12

DELTA-AMINOLEVULINIC ACID DEHYDRATASE C3LPU7 F4MUJ9 P0ACB2 P13716 Q59643 Q5GSR3 Q9VTV9

Ki: 21 IC50: 54 EC50: 12

Delta-aminolevulinic acid dehydratase P0ACB2

Escherichia coli (strain K12)

Ki: 20 EC50: 3

Delta-aminolevulinic acid dehydratase P13716

Human

Ki: 1 IC50: 20

Delta-aminolevulinic acid dehydratase Q5GSR3

Wolbachia sp. subsp. Brugia malayi (strain TRS)

IC50: 14

Delta-aminolevulinic acid dehydratase C3LPU7

Vibrio cholerae

IC50: 2 EC50: 3

Delta-aminolevulinic acid dehydratase F4MUJ9

Yersinia enterocolitica W22703

EC50: 3

Delta-aminolevulinic acid dehydratase Q59643

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)

IC50: 3 EC50: 3

Delta-aminolevulinic acid dehydratase Q9VTV9

Fruit fly

IC50: 15

Delta-aminolevulinic acid dehydratase, chloroplastic P30124

Garden pea

IC50: 15

DELTA-TYPE OPIOID RECEPTOR O55242 P32300 P33533 P33534 P33535 P34975 P35372 P41143 P41145 P42866 P79291 Q9R0C9

Ki: 8453 IC50: 3450 Kd: 61 EC50: 1929

Delta-type opioid receptor P41143

Human

Ki: 5109 IC50: 1332 Kd: 11 EC50: 1726

Delta-type opioid receptor P33533

Rat

Ki: 2450 IC50: 528 Kd: 28 EC50: 86

Delta-type opioid receptor P79291

Pig

Ki: 69

Delta-type opioid receptor P32300

Mouse

Ki: 719 IC50: 971 Kd: 8 EC50: 47

Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 O55242 P32300 P33534 P42866

Mouse

IC50: 66

Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 P33533 P33535 P34975 Q9R0C9

Rat

Ki: 89 IC50: 362 Kd: 12 EC50: 14

Delta-type/Kappa-type/Mu-type opioid receptor P33533 P33535 P34975

Rat

Ki: 2 IC50: 55 Kd: 2 EC50: 42

Delta-type/Kappa-type/Mu-type opioid receptor P35372 P41143 P41145

Human

Ki: 1 IC50: 136

Delta-type/Kappa-type/Mu-type opioid receptor P32300 P33534 P42866

Mouse

Ki: 14

Delta-type/Mu-type opioid receptor P32300 P42866

Mouse

EC50: 14

DEOXYCYTIDINE KINASE P27707 P43346

Ki: 22 IC50: 157 EC50: 55

Deoxycytidine kinase P27707

Human

Ki: 22 IC50: 125 EC50: 54

Deoxycytidine kinase P43346

Mouse

IC50: 32 EC50: 1

Deoxyguanosine kinase, mitochondrial Q16854

Human

IC50: 1

Deoxyhypusine hydroxylase Q9BU89

Human

IC50: 5

DEOXYHYPUSINE SYNTHASE P49366 Q6AY53 Q9GSW0

Ki: 2 IC50: 136

Deoxyhypusine synthase P49366

Human

IC50: 85

Deoxyhypusine synthase Q6AY53

Rat

IC50: 51

Deoxyhypusine synthase Q9GSW0

malaria parasite P. falciparum

Ki: 2

Deoxynucleoside kinase Q9XZT6

Fruit fly

IC50: 67

DEOXYPYRIMIDINE KINASE A3RLP8 O72346 P04407 P06479 P09250 P13159 Q0H0G9 Q6L709 Q6QCL9 Q9PPP5 Q9QNF7

Ki: 9 IC50: 470 EC50: 303

Thymidine kinase O72346

HHV-1

Ki: 1 IC50: 29

Thymidine kinase P04407

HHV-2

Ki: 1 IC50: 29

Thymidine kinase Q9QNF7

HHV-1

Ki: 1 IC50: 61

Thymidine kinase P09250

HHV-3

IC50: 55

Thymidine kinase Q6L709

HHV-2

IC50: 85

Thymidine kinase Q0H0G9

Staphylococcus aureus

Ki: 2

Thymidine kinase Q9PPP5

Ureaplasma parvum

IC50: 10

Thymidine kinase P13159

FeHV-1

IC50: 4

Thymidine kinase Q9QNF7

HHV-1

Ki: 2 IC50: 49

Thymidine kinase A3RLP8

CeHV-1

IC50: 17

Thymidine kinase P06479

HHV-1

Ki: 2 IC50: 127 EC50: 97

Thymidine kinase Q6QCL9

HHV-3

IC50: 4 EC50: 206

Deoxyribonuclease gamma Q13609

Human

IC50: 5

DEOXYRIBONUCLEASE-1 P00639 P24855

IC50: 73

Deoxyribonuclease-1 P00639

Bovine

IC50: 13

Deoxyribonuclease-1 P24855

Human

IC50: 60

DEOXYRIBONUCLEASE-2-ALPHA O00115 O62855

Ki: 1 IC50: 4

Deoxyribonuclease-2-alpha O62855

Pig

IC50: 4

Deoxyribonuclease-2-alpha O00115

Human

Ki: 1

Deoxyuridine 5'-triphosphate nucleotidohydrolase Q8II92

Plasmodium falciparum (isolate 3D7)

Ki: 113

Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial P33316

Human

Ki: 156 IC50: 294 EC50: 21

Deoxyuridine triphosphatase, putative Q4DI50

Trypanosoma cruzi (strain CL Brener)

Ki: 12

DEP domain-containing mTOR-interacting protein Q8TB45

Human

Kd: 1

Deubiquitinase OTUD6B Q8N6M0

Human

IC50: 1

Deubiquitinating protein VCPIP1 Q96JH7

Human

IC50: 1

Diacylglycerol acyltransferase/mycolyltransferase Ag85C P9WQN9

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 35

Diacylglycerol kinase 1 Q01583

Fruit fly

IC50: 4

DIACYLGLYCEROL KINASE ALPHA P20192 P23743 P51556 Q13574

Ki: 8 IC50: 3998

Diacylglycerol kinase alpha P23743

Human

Ki: 8 IC50: 3737

Diacylglycerol kinase alpha P20192

Pig

IC50: 7

Diacylglycerol kinase alpha P51556

Rat

IC50: 2

Diacylglycerol kinase alpha [9-727] P23743

Human

IC50: 251

Diacylglycerol kinase alpha/zeta P23743 Q13574

Human

IC50: 1

Diacylglycerol kinase beta Q9Y6T7

Human

IC50: 5

Diacylglycerol kinase delta Q16760

Human

IC50: 126

Diacylglycerol kinase gamma P49619

Human

IC50: 5

Diacylglycerol kinase iota O75912

Human

IC50: 6

Diacylglycerol kinase kappa Q5KSL6

Human

IC50: 2

DIACYLGLYCEROL KINASE ZETA P23743 Q13574

Human

IC50: 2530

Diacylglycerol kinase alpha/zeta P23743 Q13574

Human

IC50: 1

Diacylglycerol kinase zeta Q13574

Human

IC50: 13

Diacylglycerol kinase zeta Q13574

Human

IC50: 2516

DIACYLGLYCEROL LIPASE-ALPHA Q6WQJ1 Q9Y4D2

Ki: 8 IC50: 412

Diacylglycerol lipase-alpha Q9Y4D2

Human

Ki: 1 IC50: 385

Diacylglycerol lipase-alpha Q6WQJ1

Mouse

Ki: 7 IC50: 27

DIACYLGLYCEROL LIPASE-BETA Q8NCG7 Q91WC9

IC50: 94

Diacylglycerol lipase-beta Q8NCG7

Human

IC50: 70

Diacylglycerol lipase-beta Q91WC9

Mouse

IC50: 24

DIACYLGLYCEROL O-ACYLTRANSFERASE 1 O75907 Q9ERM3 Q9Z2A7

Ki: 17 IC50: 2104 EC50: 56

Diacylglycerol O-acyltransferase 1 O75907

Human

Ki: 17 IC50: 1742 EC50: 45

Diacylglycerol O-acyltransferase 1 Q9Z2A7

Mouse

IC50: 313 EC50: 11

Diacylglycerol O-acyltransferase 1 Q9ERM3

Rat

IC50: 34

Diacylglycerol O-acyltransferase 1 [89-488] O75907

Human

IC50: 15

DIACYLGLYCEROL O-ACYLTRANSFERASE 2 Q5FVP8 Q96PD7

IC50: 2044 Other: 2

Diacylglycerol O-acyltransferase 2 Q96PD7

Human

IC50: 2042 Other: 2

Diacylglycerol O-acyltransferase 2 Q5FVP8

Rat

IC50: 2

Diacylglycerol O-acyltransferase 2-like protein 6 Q6ZPD8

Human

IC50: 1

Diamine acetyltransferase 1 P21673

Human

Ki: 3 IC50: 2

DIAMINE OXIDASE [COPPER-CONTAINING] P19801 P36633 Q9TRC7

Ki: 12 IC50: 98

Amiloride-sensitive amine oxidase [copper-containing] P19801

Human

Ki: 12 IC50: 59

Amiloride-sensitive amine oxidase [copper-containing] P36633

Rat

IC50: 22

Amiloride-sensitive amine oxidase [copper-containing] Q9TRC7

Pig

IC50: 17

DICKKOPF-RELATED PROTEIN 1 O54908 O94907

IC50: 1 EC50: 6

Dickkopf-related protein 1 O94907

Human

EC50: 6

Dickkopf-related protein 1 O54908

Mouse

IC50: 1

DIHYDROFOLATE REDUCTASE A0A0B4ZMU3 A0A0W4ZHR8 A0EPY1 B0BL08 C7C2U7 J7IFZ2 O30463 P00374 P00375 P00376 P00378 P00381 P07807 P0A017 P0ABQ4 P16184 P22906 P9WNX1 Q4H3Y3 Q54801 Q6FPH0 Q81E04 Q81R22 Q8NWQ9 Q8Z9J9 Q920D2 Q9UUP5

Ki: 2014 IC50: 5337 Kd: 152 EC50: 7 Koff: 5 Kon: 5 Other: 1

Dihydrofolate reductase A0A0W4ZHR8

Human pneumocystis pneumonia agent

IC50: 10

Dihydrofolate reductase A0EPY1

Human pneumocystis pneumonia agent

IC50: 18

Dihydrofolate reductase P22906

Yeast

Ki: 18 IC50: 116

Dihydrofolate reductase P00374

Human

Ki: 516 IC50: 1537 Kd: 87 EC50: 6 Other: 1

Dihydrofolate reductase P0ABQ4

Escherichia coli (strain K12)

Ki: 30 IC50: 173 Kd: 2 EC50: 1

Dihydrofolate reductase Q81R22

Bacillus anthracis

Ki: 18 IC50: 46

Dihydrofolate reductase O30463

Mycobacterium avium

IC50: 158

Dihydrofolate reductase P0A017

Staphylococcus aureus

Ki: 133 IC50: 68

Dihydrofolate reductase Q54801

Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

Ki: 2 IC50: 4

Dihydrofolate reductase P16184

Pneumocystis carinii

Ki: 56 IC50: 894

Dihydrofolate reductase A0A0B4ZMU3

Streptococcus pneumoniae

Ki: 2 IC50: 2

Dihydrofolate reductase Q920D2

Rat

Ki: 14 IC50: 1207

Dihydrofolate reductase Q81E04

Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)

IC50: 27

Dihydrofolate reductase P00375

Mouse

Ki: 110 IC50: 100

Dihydrofolate reductase Q6FPH0

Yeast

IC50: 25

Dihydrofolate reductase J7IFZ2

Streptococcus pyogenes (Firmicutes)

IC50: 15

Dihydrofolate reductase Q4H3Y3

Staphylococcus aureus

IC50: 9

Dihydrofolate reductase C7C2U7

Staphylococcus aureus

IC50: 9

Dihydrofolate reductase P00376

Bovine

Ki: 121 IC50: 360

Dihydrofolate reductase B0BL08

Escherichia coli

Ki: 384 IC50: 170 Kd: 57 Koff: 5 Kon: 5

Dihydrofolate reductase P00378

Chicken

Ki: 288 IC50: 19 Kd: 6

Dihydrofolate reductase P07807

Baker's yeast

IC50: 49

Dihydrofolate reductase P00381

Lactobacillus casei

Ki: 261 IC50: 212

Dihydrofolate reductase Q8NWQ9

Staphylococcus aureus (strain MW2)

IC50: 11

Dihydrofolate reductase P9WNX1

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Ki: 1 IC50: 47

Dihydrofolate reductase Q8Z9J9

Salmonella typhi

Ki: 58

Dihydrofolate reductase Q9UUP5

Human pneumocystis pneumonia agent

IC50: 30

Dihydrofolate reductase O30463 P0ABQ4

Mycobacterium avium

IC50: 19

Dihydrofolate reductase [F98Y] P0A017

Staphylococcus aureus (strain NCTC 8325 / PS 47)

Ki: 2 IC50: 2

Dihydrofolate reductase type 1 P00382

Escherichia coli

Ki: 43

Dihydrofolate reductase type 1 from Tn4003 P13955

Staphylococcus aureus

IC50: 9

Dihydrofolate synthase/folylpolyglutamate synthase P08192

Escherichia coli (strain K12)

Ki: 1

DIHYDROLIPOYL DEHYDROGENASE P9WHH8 P9WHH9 Q6KCB6

Ki: 5 IC50: 147 Other: 1

Dihydrolipoyl dehydrogenase P9WHH8

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

Ki: 5 IC50: 22

Dihydrolipoyl dehydrogenase P9WHH9

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 124 Other: 1

Dihydrolipoyl dehydrogenase Q6KCB6

malaria parasite P. falciparum

IC50: 1

Dihydrolipoyl dehydrogenase, mitochondrial P09623

Pig

IC50: 1

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex P9WIS7

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 54

Pyruvate dehydrogenase complex component E2 P10515

Human

Kd: 1

DIHYDROOROTASE P05020 Q81WF0

Ki: 3 IC50: 2 Kd: 17

Dihydroorotase P05020

Escherichia coli (strain K12)

Ki: 3

Dihydroorotase Q81WF0

Bacillus anthracis

IC50: 2 Kd: 17

DIHYDROOROTATE DEHYDROGENASE (FUMARATE) P28272 Q4QEW7

IC50: 126

Dihydroorotate dehydrogenase (fumarate) P28272

Baker's yeast

IC50: 14

Dihydroorotate dehydrogenase (fumarate) Q4QEW7

Leishmania major

IC50: 112

DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL A0A0L7M6L3 A0A1G4H0K4 A0A509AEH5 A0A8I3N262 A5K1N1 G4VFD7 O35435 Q02127 Q08210 Q54A96 Q63707

Ki: 296 IC50: 4313 Kd: 4 EC50: 43

Dihydroorotate dehydrogenase (quinone), mitochondrial A0A1G4H0K4

malaria parasite P. vivax

IC50: 13

Dihydroorotate dehydrogenase (quinone), mitochondrial Q08210

Plasmodium falciparum (isolate 3D7)

Ki: 32 IC50: 212 EC50: 12

Dihydroorotate dehydrogenase (quinone), mitochondrial A0A8I3N262

Dog

IC50: 7

Dihydroorotate dehydrogenase (quinone), mitochondrial A0A0L7M6L3

Plasmodium falciparum (isolate Dd2)

EC50: 5

Dihydroorotate dehydrogenase (quinone), mitochondrial Q54A96

malaria parasite P. falciparum

IC50: 248

Dihydroorotate dehydrogenase (quinone), mitochondrial Q63707

Rat

IC50: 139 Kd: 1

Dihydroorotate dehydrogenase (quinone), mitochondrial A5K1N1

Plasmodium vivax

IC50: 11

Dihydroorotate dehydrogenase (quinone), mitochondrial Q02127

Human

Ki: 264 IC50: 3420 Kd: 3 EC50: 26

Dihydroorotate dehydrogenase (quinone), mitochondrial G4VFD7

Blood fluke

IC50: 32

Dihydroorotate dehydrogenase (quinone), mitochondrial O35435

Mouse

IC50: 105

Dihydroorotate dehydrogenase (quinone), mitochondrial [100-517] A0A509AEH5

Plasmodium berghei (strain Anka)

IC50: 53

Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] Q02127

Human

IC50: 45

Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] Q63707

Rat

IC50: 2

Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] Q54A96

malaria parasite P. falciparum

IC50: 13

Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] Q54A96

malaria parasite P. falciparum

IC50: 13

Putative dihydropicolinate synthase Q93RY0

Streptomyces coelicolor

Ki: 1 IC50: 18

DIHYDROPTERIDINE REDUCTASE P09417 P11348

Ki: 4

Dihydropteridine reductase P11348

Rat

Ki: 3

Dihydropteridine reductase P09417

Human

Ki: 1

DIHYDROPTEROATE SYNTHASE P0AC13 Q81VW8

IC50: 28 Kd: 14

Dihydropteroate synthase P0AC13

Escherichia coli (strain K12)

Kd: 12

Dihydropteroate synthase Q81VW8

Bacillus anthracis

IC50: 28 Kd: 2

Dihydropyrimidine dehydrogenase [NADP(+)] Q12882

Human

IC50: 6

Dihydroxyacetone phosphate acyltransferase O15228

Human

Ki: 3 IC50: 4

Dioxygenase O87171

Pseudomonas paucimobilis

Ki: 1 IC50: 7

DIPEPTIDASE 1 P16444 P22412

Ki: 188 IC50: 33

Dipeptidase 1 P16444

Human

IC50: 33

Dipeptidase 1 P22412

Pig

Ki: 188

Dipeptidyl carboxypeptidase P24171

Escherichia coli (strain K12)

IC50: 1

DIPEPTIDYL PEPTIDASE 1 O97578 P53634 P80067 P97821 Q3ZCJ8

Ki: 38 IC50: 2381 Kd: 1

Dipeptidyl peptidase 1 P53634

Human

Ki: 30 IC50: 2355 Kd: 1

Dipeptidyl peptidase 1 P97821

Mouse

Ki: 8 IC50: 21

Dipeptidyl peptidase 1 Q3ZCJ8

Bovine

IC50: 3

Dipeptidyl peptidase 1 O97578

Dog

IC50: 1

Dipeptidyl peptidase 1 P80067

Rat

IC50: 1

DIPEPTIDYL PEPTIDASE 2 Q9EPB1 Q9UHL4

Ki: 42 IC50: 1903

Dipeptidyl peptidase 2 Q9UHL4

Human

Ki: 42 IC50: 1888

Dipeptidyl peptidase 2 Q9EPB1

Rat

IC50: 15

DIPEPTIDYL PEPTIDASE 3 L8I2E6 Q9NY33

Ki: 8 IC50: 51 Kd: 1

Dipeptidyl peptidase 3 Q9NY33

Human

Ki: 1 IC50: 44 Kd: 1

Dipeptidyl peptidase 3 L8I2E6

wild yak

Ki: 7 IC50: 7

DIPEPTIDYL PEPTIDASE 4 P14740 P22411 P27487 P28843 P81425

Ki: 669 IC50: 5947 Kd: 26 EC50: 4 Other: 1

Dipeptidyl peptidase 4 P27487

Human

Ki: 621 IC50: 5538 Kd: 26 EC50: 4

Dipeptidyl peptidase 4 P22411

Pig

Ki: 40 IC50: 93 Other: 1

Dipeptidyl peptidase 4 P14740

Rat

Ki: 8 IC50: 216

Dipeptidyl peptidase 4 P81425

Bovine

IC50: 5

Dipeptidyl peptidase 4 P28843

Mouse

IC50: 63

Dipeptidyl peptidase 4 [K6R,T557I] P27487

Human

IC50: 32

DIPEPTIDYL PEPTIDASE 8 Q6V1X1 Q86TI2

Human

Ki: 225 IC50: 2028 Kd: 4

Dipeptidyl peptidase 8 Q6V1X1

Human

Ki: 225 IC50: 1951 Kd: 4

Dipeptidyl peptidase 8/9 Q6V1X1 Q86TI2

Human

IC50: 77

DIPEPTIDYL PEPTIDASE 9 E1BI31 Q6V1X1 Q86TI2

Ki: 218 IC50: 1628

Dipeptidyl peptidase 8/9 Q6V1X1 Q86TI2

Human

IC50: 77

Dipeptidyl peptidase 9 Q86TI2

Human

Ki: 203 IC50: 1544

Dipeptidyl peptidase 9 E1BI31

Bovine

IC50: 7

Dipeptidyl peptidase 9 [D301A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [E286A,E297A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [E286A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [H289A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [I288A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [K299A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [L295A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [R298A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [S292A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [V285A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [V290A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [Y277A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [Y303D] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [Y305A] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase 9 [Y305D] Q86TI2

Human

Ki: 1

Dipeptidyl peptidase IV O31048

Porphyromonas gingivalis

Ki: 1 IC50: 76

DIPEPTIDYL-PEPTIDASE IV E1BI31 Q86TI2

Ki: 203 IC50: 1551

Dipeptidyl peptidase 9 Q86TI2

Human

Ki: 203 IC50: 1544

Dipeptidyl peptidase 9 E1BI31

Bovine

IC50: 7

DIPHOSPHOMEVALONATE DECARBOXYLASE A0A0H2ZN59 P53602

Ki: 2 IC50: 353

Diphosphomevalonate decarboxylase A0A0H2ZN59

Streptococcus pneumoniae D39

IC50: 348

Diphosphomevalonate decarboxylase P53602

Human

Ki: 2 IC50: 5

Disabled homolog 2 P98082

Human

Ki: 3

DISCOIDIN DOMAIN-CONTAINING RECEPTOR 2 Q16832

Human

Ki: 25 IC50: 455 Kd: 183 EC50: 2

Discoidin domain-containing receptor 2 Q16832

Human

Ki: 25 IC50: 455 Kd: 170 EC50: 2

Discoidin domain-containing receptor 2 [A642S] Q16832

Human

Kd: 13

Disintegrin and metalloproteinase domain-containing protein 10 O14672

Human

Ki: 20 IC50: 782

Disintegrin and metalloproteinase domain-containing protein 12 O43184

Human

IC50: 5

DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17 O77636 P78536 Q9Z0F8 Q9Z1K9

Ki: 535 IC50: 3750 EC50: 10

Disintegrin and metalloproteinase domain-containing protein 17 P78536

Human

Ki: 425 IC50: 3241 EC50: 10

Disintegrin and metalloproteinase domain-containing protein 17 O77636

Pig

Ki: 23 IC50: 403

Disintegrin and metalloproteinase domain-containing protein 17 Q9Z0F8

Mouse

Ki: 1 IC50: 98

Disintegrin and metalloproteinase domain-containing protein 17 Q9Z1K9

Rat

IC50: 8

Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] P78536

Human

Ki: 86

Disintegrin and metalloproteinase domain-containing protein 33 Q9BZ11

Human

Ki: 1 IC50: 13

Disintegrin and metalloproteinase domain-containing protein 8 P78325

Human

IC50: 28

Disintegrin and metalloproteinase domain-containing protein 9 Q13443

Human

Ki: 2 IC50: 69

Disks large homolog 4 P78352

Human

Ki: 130

Disulfide bond formation protein B P0A6M2

Escherichia coli (strain K12)

IC50: 8

DITRANS,POLYCIS-UNDECAPRENYL-DIPHOSPHATE SYNTHASE ((2E,6E)-FARNESYL-DIPHOSPHATE SPECIFIC) A0A080SPQ8 P60472 Q9HXY2 V5VCK8

IC50: 9

Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) Q9HXY2

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)

IC50: 2

Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) A0A080SPQ8

Pseudomonas aeruginosa (g-Proteobacteria)

IC50: 2

Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) V5VCK8

Acinetobacter baumannii

IC50: 2

Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) P60472

Escherichia coli (strain K12)

IC50: 3

DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 P13864 P26358

Ki: 3 IC50: 1191 Kd: 2 EC50: 22

DNA (cytosine-5)-methyltransferase 1 P26358

Human

Ki: 3 IC50: 1172 EC50: 22

DNA (cytosine-5)-methyltransferase 1 P13864

Mouse

IC50: 13 Kd: 2

DNA (cytosine-5)-methyltransferase 1 [351-1600] P26358

Human

IC50: 1

DNA (cytosine-5)-methyltransferase 1 [601-1600] P26358

Human

IC50: 2

DNA (cytosine-5)-methyltransferase 1 [621-1600] P26358

Human

IC50: 3

DNA (CYTOSINE-5)-METHYLTRANSFERASE 3-LIKE Q9UBC3 Q9UJW3 Q9Y6K1

Human

IC50: 21

DNA (cytosine-5)-methyltransferase 3-like Q9UJW3

Human

IC50: 19

DNA (cytosine-5)-methyltransferase 3-like/3A Q9UJW3 Q9Y6K1

Human

IC50: 1

DNA (cytosine-5)-methyltransferase 3-like/3B Q9UBC3 Q9UJW3

Human

IC50: 1

DNA (CYTOSINE-5)-METHYLTRANSFERASE 3A O88508 Q9UJW3 Q9Y6K1

Ki: 8 IC50: 111 Kd: 6 EC50: 26

DNA (cytosine-5)-methyltransferase 3-like/3A Q9UJW3 Q9Y6K1

Human

IC50: 1

DNA (cytosine-5)-methyltransferase 3A Q9Y6K1

Human

Ki: 8 IC50: 106 EC50: 26

DNA (cytosine-5)-methyltransferase 3A O88508

Mouse

IC50: 3 Kd: 6

DNA (cytosine-5)-methyltransferase 3A [590-912] Q9Y6K1

Human

IC50: 1

DNA (CYTOSINE-5)-METHYLTRANSFERASE 3B O88509 Q9UBC3 Q9UJW3

IC50: 70 EC50: 11

DNA (cytosine-5)-methyltransferase 3-like/3B Q9UBC3 Q9UJW3

Human

IC50: 1

DNA (cytosine-5)-methyltransferase 3B Q9UBC3

Human

IC50: 66 EC50: 11

DNA (cytosine-5)-methyltransferase 3B O88509

Mouse

IC50: 3

DNA helicase [35-727] Q8I3W6

malaria parasite P. falciparum

IC50: 9

DNA adenine methylase P0AEE8

Escherichia coli K-12

IC50: 5

DNA cross-link repair 1A protein Q6PJP8

Human

IC50: 3

DNA DAMAGE-BINDING PROTEIN 1 O60885 Q16531 Q96SW2

Human

IC50: 248 Kd: 838

Bromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon O60885 Q16531 Q96SW2

Human

IC50: 37

DNA damage-binding protein 1 Q16531

Human

IC50: 1 Kd: 192

DNA damage-binding protein 1/Protein Cereblon [40-442] Q16531 Q96SW2

Human

IC50: 9

DNA damage-binding protein 1/Protein cereblon Q16531 Q96SW2

Human

IC50: 201 Kd: 646

DNA damage-inducible transcript 3 protein P35639

Mouse

IC50: 1880

DNA dC->dU-editing enzyme APOBEC-3A P31941

Human

IC50: 777

DNA dC->dU-editing enzyme APOBEC-3G Q9HC16

Human

IC50: 1055

DNA excision repair protein ERCC-1/repair endonuclease XPF P07992 Q92889

Human

Kd: 1

DNA excision repair protein ERCC-5 P28715

Human

IC50: 128

DNA gyrase inhibitor P33012

Escherichia coli (strain K12)

IC50: 110

DNA GYRASE SUBUNIT A C3SLN2 P05652 P05653 P0A0K8 P0AES4 P0AES6 P20831 P66936 P9WG45 P9WG47 Q47245 Q59556 Q932M0

Ki: 51 IC50: 1504 Kd: 8

DNA gyrase subunit A P20831

Staphylococcus aureus

IC50: 77

DNA gyrase subunit A P0AES4

Escherichia coli (strain K12)

IC50: 139

DNA gyrase subunit A P9WG47

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 12

DNA gyrase subunit A Q59556

Mycobacterium smegmatis

IC50: 8

DNA gyrase subunit A Q47245

Escherichia coli

IC50: 13

DNA gyrase subunit A/B P05652 P05653

Bacillus subtilis (strain 168)

IC50: 5

DNA gyrase subunit A/B P0A0K8 P20831

Staphylococcus aureus

Ki: 26 IC50: 506

DNA gyrase subunit A/B P0AES4 P0AES6

Escherichia coli (strain K12)

Ki: 25 IC50: 741 Kd: 8

DNA gyrase subunit A/B P9WG45 P9WG47

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 1

DNA gyrase subunit A/B P66936 Q932M0

Staphylococcus aureus subsp. aureus Mu50

IC50: 1

DNA gyrase subunit A/B C3SLN2 Q47245

Escherichia coli

IC50: 1

DNA GYRASE SUBUNIT B C3SLN2 C3SLN3 P05652 P05653 P0A0K8 P0A4L9 P0AES4 P0AES6 P0C559 P20831 P66936 P9WG45 P9WG47 Q47245 Q932M0

Ki: 54 IC50: 2336 Kd: 16 ITC: 4

DNA Gyrase C3SLN3

Escherichia coli

IC50: 46 ITC: 4

DNA gyrase subunit A/B P05652 P05653

Bacillus subtilis (strain 168)

IC50: 5

DNA gyrase subunit A/B P0A0K8 P20831

Staphylococcus aureus

Ki: 26 IC50: 506

DNA gyrase subunit A/B P0AES4 P0AES6

Escherichia coli (strain K12)

Ki: 25 IC50: 741 Kd: 8

DNA gyrase subunit A/B P9WG45 P9WG47

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 1

DNA gyrase subunit A/B P66936 Q932M0

Staphylococcus aureus subsp. aureus Mu50

IC50: 1

DNA gyrase subunit A/B C3SLN2 Q47245

Escherichia coli

IC50: 1

DNA gyrase subunit B P0A0K8

Staphylococcus aureus

Ki: 1 IC50: 371

DNA gyrase subunit B P0AES6

Escherichia coli (strain K12)

Ki: 2 IC50: 149 Kd: 6

DNA gyrase subunit B C3SLN2

Escherichia coli

Kd: 2

DNA gyrase subunit B P0A4L9

Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

IC50: 35

DNA gyrase subunit B P0C559

Mycobacterium smegmatis

IC50: 353

DNA gyrase subunit B P9WG45

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 121

DNA gyrase subunit B P66936

Staphylococcus aureus subsp. aureus Mu50

IC50: 6

DNA helicase IV P15038

Escherichia coli (strain K12)

IC50: 5

DNA LIGASE P00970 Q9AIU7

IC50: 80 Kd: 3

DNA ligase P00970

Enterobacteria phage T4

IC50: 11

DNA ligase Q9AIU7

Staphylococcus aureus

IC50: 69 Kd: 3

DNA ligase 1 P18858

Human

Ki: 112 IC50: 102

DNA ligase 3 P49916

Human

IC50: 2

DNA ligase 4 P49917

Human

IC50: 1

DNA ligase A P9WNV1

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 13

DNA NUCLEOTIDYLEXOTRANSFERASE P04053 P06526

Ki: 6 IC50: 29

DNA nucleotidylexotransferase P04053

Human

Ki: 6 IC50: 20

DNA nucleotidylexotransferase P06526

Bovine

IC50: 9

DNA oxidative demethylase ALKBH2 Q6NS38

Human

IC50: 20

DNA polymerase P06856

VACV

IC50: 35

DNA POLYMERASE ALPHA CATALYTIC SUBUNIT P09884 P26019

Ki: 23 IC50: 119 EC50: 26

DNA polymerase alpha catalytic subunit P09884

Human

Ki: 23 IC50: 115 EC50: 26

DNA polymerase alpha catalytic subunit P26019

Fruit fly

IC50: 4

DNA polymerase alpha subunit B Q58D13

Bovine

Ki: 2 IC50: 10

DNA POLYMERASE BETA P06746 P06766 Q8K409

Ki: 17 IC50: 319 Kd: 1

DNA polymerase beta P06746

Human

Ki: 5 IC50: 206 Kd: 1

DNA polymerase beta Q8K409

Mouse

IC50: 22

DNA polymerase beta P06766

Rat

Ki: 12 IC50: 91

DNA POLYMERASE CATALYTIC SUBUNIT P04292 P04293 P08546 P09252 P28857

IC50: 217

DNA polymerase catalytic subunit P08546

HHV-5

IC50: 104

DNA polymerase catalytic subunit P04293

HHV-1

IC50: 61

DNA polymerase catalytic subunit P28857

HHV-6 variant A

IC50: 36

DNA polymerase catalytic subunit P09252

HHV-3

IC50: 12

DNA polymerase catalytic subunit P04292

HHV-1

IC50: 4

DNA POLYMERASE DELTA CATALYTIC SUBUNIT P28340 P54358

IC50: 21

DNA polymerase delta catalytic subunit P54358

Fruit fly

IC50: 4

DNA polymerase delta catalytic subunit P28340

Human

IC50: 17

DNA polymerase eta Q9Y253

Human

IC50: 49

DNA polymerase I P00582

Escherichia coli (strain K12)

IC50: 4

DNA polymerase I, thermostable P19821

Thermus aquaticus

IC50: 53 EC50: 43

DNA POLYMERASE III POLC-TYPE P0C1P9 P13267

Ki: 153 IC50: 18

DNA polymerase III PolC-type P13267

Bacillus subtilis (strain 168)

Ki: 153

DNA polymerase III PolC-type P0C1P9

Staphylococcus aureus

IC50: 18

DNA POLYMERASE III SUBUNIT ALPHA O34623 P10443

Ki: 51

DNA polymerase III subunit alpha O34623

Bacillus subtilis (strain 168)

Ki: 27

DNA polymerase III subunit alpha P10443

Escherichia coli (strain K12)

Ki: 24

DNA polymerase III subunit tau P06710

Escherichia coli (strain K12)

Ki: 13

DNA POLYMERASE IOTA Q6R3M4 Q9UNA4

IC50: 12

DNA polymerase iota Q6R3M4

Mouse

IC50: 8

DNA polymerase iota Q9UNA4

Human

IC50: 4

DNA polymerase kappa Q9UBT6

Human

Ki: 2 IC50: 18

DNA POLYMERASE LAMBDA Q9QXE2 Q9UGP5

IC50: 59

DNA polymerase lambda Q9UGP5

Human

IC50: 55

DNA polymerase lambda Q9QXE2

Mouse

IC50: 4

DNA polymerase nu Q7Z5Q5

Human

IC50: 4

DNA polymerase subunit gamma-1 P54098

Human

Ki: 2 IC50: 29 Kd: 2

DNA polymerase theta O75417

Human

IC50: 242 Kd: 14

DNA PRIMASE A0A6L8PXB3 P10236 P9WNW0

IC50: 19

DNA primase A0A6L8PXB3

Bacillus anthracis

IC50: 5

DNA primase P9WNW0

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

IC50: 2

DNA primase P10236

HHV-1

IC50: 12

DNA primase TraC P27189

Escherichia coli

IC50: 1

DNA repair and recombination protein RAD54-like Q92698

Human

EC50: 1

DNA repair and recombination protein RadA O74036

Pyrococcus furiosus

Kd: 8

DNA REPAIR ENDONUCLEASE XPF P07992 Q92889

Human

IC50: 4 Kd: 3

DNA excision repair protein ERCC-1/repair endonuclease XPF P07992 Q92889

Human

Kd: 1

DNA repair endonuclease XPF Q92889

Human

IC50: 4 Kd: 2

DNA-(apurinic or apyrimidinic site) endonuclease P27695

Human

Ki: 27 IC50: 296 Kd: 4 Other: 8

DNA repair protein complementing XP-A cells P23025

Human

IC50: 32

DNA REPAIR PROTEIN RAD51 HOMOLOG 1 P51587 Q06609

Human

Ki: 6 IC50: 312 Kd: 9 EC50: 214

Breast cancer type 2 susceptibility protein/DNA repair protein RAD51 homolog 1 P51587 Q06609

Human

EC50: 2

DNA repair protein RAD51 homolog 1 Q06609

Human

Ki: 6 IC50: 312 Kd: 9 EC50: 212

DNA repair protein RAD52 homolog P43351

Human

IC50: 14

DNA repair protein REV1 Q9UBZ9

Human

Ki: 20 IC50: 22 Kd: 22

DNA TOPOISOMERASE A0JN73 E9BRC0 F1MN93 Q98254

IC50: 40 Kd: 2

DNA topoisomerase A0JN73

Bovine

IC50: 4

DNA topoisomerase I E9BRC0

Leishmania donovani

IC50: 30 Kd: 2

DNA topoisomerase I F1MN93

Bovine

IC50: 4

DNA topoisomerase I Q98254

MOCV

IC50: 2

DNA topoisomerase (ATP-hydrolyzing) Q7X1P7

Streptococcus pneumoniae

IC50: 35

DNA TOPOISOMERASE 1 A0A2S9PM60 P04786 P06612 P11387 P9WG49 Q04750 Q7YR26 Q9WUL0

Ki: 1 IC50: 755 Kd: 4 EC50: 201

DNA topoisomerase 1 P06612

Escherichia coli (strain K12)

IC50: 28

DNA topoisomerase 1 P9WG49

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 3

DNA topoisomerase 1 P11387

Human

Ki: 1 IC50: 670 Kd: 4 EC50: 171

DNA topoisomerase 1 A0A2S9PM60

Yersinia pestis

IC50: 22

DNA topoisomerase 1 Q04750

Mouse

IC50: 20 EC50: 30

DNA topoisomerase 1 Q7YR26

Green monkey

IC50: 4

DNA topoisomerase 1 Q9WUL0

Rat

IC50: 2

DNA topoisomerase 1 P04786

Baker's yeast

IC50: 6

DNA TOPOISOMERASE 2 P06786 P15348

IC50: 8

DNA topoisomerase 2 P06786

Baker's yeast

IC50: 1

DNA topoisomerase 2 P15348

Fruit fly

IC50: 7

DNA TOPOISOMERASE 2-ALPHA P11388 Q02880

Human

Ki: 2 IC50: 995 Kd: 1 EC50: 244

DNA topoisomerase 2-alpha P11388

Human

Ki: 1 IC50: 754 Kd: 1 EC50: 20

DNA topoisomerase 2-alpha/2-beta P11388 Q02880

Human

Ki: 1 IC50: 241 EC50: 224

DNA TOPOISOMERASE 2-BETA P11388 Q02880

Human

Ki: 9 IC50: 302 EC50: 247

DNA topoisomerase 2-alpha/2-beta P11388 Q02880

Human

Ki: 1 IC50: 241 EC50: 224

DNA topoisomerase 2-beta Q02880

Human

Ki: 8 IC50: 61 EC50: 23

DNA TOPOISOMERASE 2-BINDING PROTEIN 1 P49760 Q13535 Q8WXE1 Q92547

Human

Ki: 32 EC50: 18

ATR-interacting protein/DNA topoisomerase 2-binding protein 1/Dual specificity protein kinase CLK2/Serine/threonine-protein kinase ATR P49760 Q13535 Q8WXE1 Q92547

Human

Ki: 32

DNA topoisomerase 2-binding protein 1 Q92547

Human

EC50: 18

DNA topoisomerase 3 P96583

Bacillus subtilis (strain 168)

Ki: 132

DNA TOPOISOMERASE 4 SUBUNIT A P0AFI2 P0C1U9 P20083 Q2FYS4 Q2FYS5 Q45066 Q59192 Q931S2

Ki: 25 IC50: 340

DNA topoisomerase 4 subunit A P0AFI2

Escherichia coli (strain K12)

IC50: 44

DNA topoisomerase 4 subunit A P0C1U9

Staphylococcus aureus

IC50: 107

DNA topoisomerase 4 subunit A Q931S2

Staphylococcus aureus subsp. aureus Mu50

IC50: 7

DNA topoisomerase 4 subunit A [V210L]/B Q45066 Q59192

Bacillus subtilis (strain 168)

IC50: 5

DNA topoisomerase 4 subunit A/B P0AFI2 P20083

Escherichia coli (strain K12)

Ki: 22

DNA topoisomerase 4 subunit A/B P0C1U9 Q2FYS5

Staphylococcus aureus (strain NCTC 8325 / PS 47)

Ki: 2 IC50: 177

DNA topoisomerase 4 subunit A/B Q2FYS4 Q2FYS5

Staphylococcus aureus (strain NCTC 8325 / PS 47)

Ki: 1

DNA TOPOISOMERASE 4 SUBUNIT B P0AFI2 P0C1U9 P20083 Q2FYS4 Q2FYS5 Q45066 Q59192

Ki: 27 IC50: 214

DNA topoisomerase 4 subunit A [V210L]/B Q45066 Q59192

Bacillus subtilis (strain 168)

IC50: 5

DNA topoisomerase 4 subunit A/B P0AFI2 P20083

Escherichia coli (strain K12)

Ki: 22

DNA topoisomerase 4 subunit A/B P0C1U9 Q2FYS5

Staphylococcus aureus (strain NCTC 8325 / PS 47)

Ki: 2 IC50: 177

DNA topoisomerase 4 subunit A/B Q2FYS4 Q2FYS5

Staphylococcus aureus (strain NCTC 8325 / PS 47)

Ki: 1

DNA topoisomerase 4 subunit B P20083

Escherichia coli (strain K12)

IC50: 20

DNA topoisomerase 4 subunit B Q2FYS5

Staphylococcus aureus (strain NCTC 8325 / PS 47)

Ki: 2 IC50: 12

DNA TOPOISOMERASE I E9B7X3 E9BRC0 F1MN93 Q98254

IC50: 46 Kd: 2

DNA topoisomerase I E9BRC0

Leishmania donovani

IC50: 30 Kd: 2

DNA topoisomerase I F1MN93

Bovine

IC50: 4

DNA topoisomerase I Q98254

MOCV

IC50: 2

DNA topoisomerase I/type IB small subunit E9B7X3 E9BRC0

Leishmania donovani

IC50: 10

Topoisomerase I subunit B Q95Z89

Leishmania major

EC50: 4

DNA-3-methyladenine glycosylase P29372

Human

IC50: 9

DNA-3-methyladenine glycosylase 1 P05100

Escherichia coli (strain K12)

IC50: 5

DNA-BINDING PROTEIN IKAROS Q13422 Q96SW2

Human

EC50: 29

DNA-binding protein Ikaros Q13422

Human

EC50: 28

DNA-binding protein Ikaros/Protein cereblon Q13422 Q96SW2

Human

EC50: 1

DNA-binding transcriptional activator DevR/DosR P9WMF9

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 10

Virulence factor transcriptional regulator MvfR A0A072ZLE6

Pseudomonas aeruginosa

IC50: 5 Kd: 18 EC50: 8

DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT O00329 P00519 P00523 P08631 P09619 P12931 P35968 P42336 P42338 P42345 P54760 P78527 P97313 Q504U8

Ki: 43 IC50: 2762 Kd: 6 EC50: 6

DNA-dependent protein kinase catalytic subunit P78527

Human

Ki: 43 IC50: 2743 Kd: 6 EC50: 6

DNA-dependent protein kinase catalytic subunit P97313

Mouse

IC50: 3

DNA-dependent protein kinase catalytic subunit/Ephrin type-B receptor 4 P54760 P78527

Human

IC50: 1

DNA-dependent protein kinase catalytic subunit/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform P42336 P78527

Human

IC50: 2

DNA-dependent protein kinase catalytic subunit/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform P42338 P78527

Human

IC50: 2

DNA-dependent protein kinase catalytic subunit/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform O00329 P78527

Human

IC50: 2

DNA-dependent protein kinase catalytic subunit/Platelet-derived growth factor receptor beta [525-1106] P09619 P78527

Human

IC50: 1

DNA-dependent protein kinase catalytic subunit/Proto-oncogene tyrosine-protein kinase Src P12931 P78527

Human

IC50: 1

DNA-dependent protein kinase catalytic subunit/Proto-oncogene tyrosine-protein kinase Src P00523 P78527

Chicken

IC50: 1

DNA-dependent protein kinase catalytic subunit/Receptor protein-tyrosine kinase P78527 Q504U8

Human

IC50: 1

DNA-dependent protein kinase catalytic subunit/Serine/threonine-protein kinase mTOR P42345 P78527

Human

IC50: 2

DNA-dependent protein kinase catalytic subunit/Tyrosine-protein kinase ABL1 P00519 P78527

Human

IC50: 1

DNA-dependent protein kinase catalytic subunit/Tyrosine-protein kinase HCK P08631 P78527

Human

IC50: 1

DNA-dependent protein kinase catalytic subunit/Vascular endothelial growth factor receptor 2 P35968 P78527

Human

IC50: 1

DNA-directed DNA polymerase P04415

Enterobacteria phage T4

IC50: 9

DNA-directed DNA/RNA polymerase mu Q9NP87

Human

IC50: 9

DNA-directed RNA polymerase I subunit RPA1 O95602

Human

IC50: 78

DNA-directed RNA polymerase II subunit RPB1 P24928

Human

IC50: 4

DNA-DIRECTED RNA POLYMERASE SUBUNIT ALPHA P0A7Z4 P0A800 P0A8T7 P0A8V2 P66706 P9WGZ1

IC50: 61

DNA-directed RNA polymerase subunit alpha P9WGZ1

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 20

DNA-directed RNA polymerase subunit alpha P66706

Staphylococcus aureus subsp. aureus N315

IC50: 20

DNA-directed RNA polymerase subunit alpha P0A7Z4

Escherichia coli (strain K12)

IC50: 20

DNA-directed RNA polymerase subunit alpha/beta/beta'/omega P0A7Z4 P0A800 P0A8T7 P0A8V2

Escherichia coli (strain K12)

IC50: 1

DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA A0A0E2LB94 P0A7Z4 P0A800 P0A8T7 P0A8V2 P9WGY9 Q3YUZ7

IC50: 275

DNA-directed RNA polymerase subunit alpha/beta/beta'/omega P0A7Z4 P0A800 P0A8T7 P0A8V2

Escherichia coli (strain K12)

IC50: 1

DNA-directed RNA polymerase subunit beta A0A0E2LB94

Escherichia coli

IC50: 171

DNA-directed RNA polymerase subunit beta P0A8V2

Escherichia coli (strain K12)

IC50: 89

DNA-directed RNA polymerase subunit beta P9WGY9

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 8

DNA-directed RNA polymerase subunit beta [D516V] Q3YUZ7

Escherichia coli

IC50: 2

DNA-directed RNA polymerase subunit beta [H526D] Q3YUZ7

Escherichia coli

IC50: 2

DNA-directed RNA polymerase subunit beta [S531L] Q3YUZ7

Escherichia coli

IC50: 2

DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' P0A7Z4 P0A800 P0A8T7 P0A8V2 P0C1T4

IC50: 49

DNA-directed RNA polymerase subunit alpha/beta/beta'/omega P0A7Z4 P0A800 P0A8T7 P0A8V2

Escherichia coli (strain K12)

IC50: 1

DNA-directed RNA polymerase subunit beta' P0C1T4

Staphylococcus aureus

IC50: 44

DNA-directed RNA polymerase subunit beta' P0A8T7

Escherichia coli (strain K12)

IC50: 4

DNA-directed RNA polymerase subunit alpha/beta/beta'/omega P0A7Z4 P0A800 P0A8T7 P0A8V2

Escherichia coli (strain K12)

IC50: 1

DNA-directed RNA polymerase, mitochondrial O00411

Human

IC50: 107

DnaJ homolog subfamily A member 1 P31689

Human

EC50: 2

Zn finger protein Q43570

Common tobacco

Ki: 22

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit P39656

Human

Ki: 13

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 P41543

Baker's yeast

Ki: 8

Dolichyl-phosphate-mannose--protein mannosyltransferase 1 O74189

Yeast

IC50: 51

DOPAMINE BETA-HYDROXYLASE P09172 P15101 Q05754

Ki: 42 IC50: 248

Dopamine beta-hydroxylase P09172

Human

IC50: 101

Dopamine beta-hydroxylase P15101

Bovine

Ki: 42 IC50: 93

Dopamine beta-hydroxylase Q05754

Rat

IC50: 54

D1 dopamine receptor Q5I6B7

Crab-eating macaque

Ki: 4

DOPAMINE RECEPTOR D4 Q589Y6 Q8WNT0

Ki: 41

Dopamine receptor D4 Q589Y6

Dog

Ki: 40

Dopamine receptor D4 Q8WNT0

Bovine

Ki: 1

Double-strand break repair protein MRE11 P49959

Human

IC50: 46 Kd: 1

Drug resistance protein 2 Q19S54

Yeast

EC50: 11

DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE P9WH09 P9WH10

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

Ki: 2 IC50: 398

dTDP-4-dehydrorhamnose 3,5-epimerase P9WH10

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

Ki: 2 IC50: 397

dTDP-4-dehydrorhamnose 3,5-epimerase/reductase P9WH09 P9WH10

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

IC50: 1

DTDP-4-DEHYDRORHAMNOSE REDUCTASE P9WH09 P9WH10

IC50: 5

dTDP-4-dehydrorhamnose 3,5-epimerase/reductase P9WH09 P9WH10

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

IC50: 1

dTDP-4-dehydrorhamnose reductase P9WH09

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

IC50: 4

DUAL 3',5'-CYCLIC-AMP AND -GMP PHOSPHODIESTERASE 11A P0C1Q2 Q9HCR9

Ki: 15 IC50: 308 EC50: 6

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Q9HCR9

Human

Ki: 15 IC50: 296

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A P0C1Q2

Mus musculus

EC50: 6

Isoform 4 of Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (PDE11A1) Q9HCR9

Human

IC50: 2

Isoform 4 of Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (PDE11A1) 35-489] Q9HCR9

Human

IC50: 10

Dual oxidase 1 Q9NRD9

Human

IC50: 1

Dual oxidase 2 Q9NRD8

Human

IC50: 1

Dual serine/threonine and tyrosine protein kinase Q6XUX3

Human

IC50: 7 Kd: 73

DUAL SPECIFICITY CALCIUM/CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1A O76074 P14100 P54750 Q01061 Q01064 Q14123

Ki: 28 IC50: 2686 Kd: 8

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A P54750

Human

Ki: 19 IC50: 2152 Kd: 8

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A P14100

Bovine

Ki: 1 IC50: 21

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B P14100 Q01061

Bovine

IC50: 84

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C P54750 Q01064 Q14123

Human

Ki: 8 IC50: 377

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C/cGMP-specific 3',5'-cyclic phosphodiesterase O76074 P54750 Q01064 Q14123

Human

IC50: 51

Isoform 6 of Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (PDE1A1) P54750

Human

IC50: 1

DUAL SPECIFICITY CALCIUM/CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1B O76074 P14100 P54750 Q01061 Q01064 Q01066 Q14123 Q63421 Q9EPR9

Ki: 12 IC50: 3418 EC50: 221

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B P14100 Q01061

Bovine

IC50: 84

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C P54750 Q01064 Q14123

Human

Ki: 8 IC50: 377

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C/cGMP-specific 3',5'-cyclic phosphodiesterase O76074 P54750 Q01064 Q14123

Human

IC50: 51

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Q01064

Human

Ki: 4 IC50: 2837 EC50: 221

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Q01061

Bovine

IC50: 6

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B/Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C/Phosphodiesterase Q01066 Q63421 Q9EPR9

Rat

IC50: 63

DUAL SPECIFICITY CALCIUM/CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1C O76074 P54750 Q01064 Q01066 Q14123 Q63421 Q9EPR9

Ki: 8 IC50: 2709

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C P54750 Q01064 Q14123

Human

Ki: 8 IC50: 377

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C/cGMP-specific 3',5'-cyclic phosphodiesterase O76074 P54750 Q01064 Q14123

Human

IC50: 51

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B/Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C/Phosphodiesterase Q01066 Q63421 Q9EPR9

Rat

IC50: 63

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C Q14123

Human

IC50: 2218

DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 P04049 P15056 P28482 P29678 P31938 P36506 P36507 Q01986 Q02750

Ki: 3 IC50: 1702 Kd: 184 EC50: 74

Dual specificity mitogen-activated protein kinase kinase 1 Q02750

Human

Ki: 3 IC50: 1301 Kd: 184 EC50: 74

Dual specificity mitogen-activated protein kinase kinase 1 P29678

Rabbit

IC50: 1

Dual specificity mitogen-activated protein kinase kinase 1 P31938

Mouse

IC50: 3

Dual specificity mitogen-activated protein kinase kinase 1 [2-31,52-393,S218E,S222D] Q02750

Human

IC50: 44

Dual specificity mitogen-activated protein kinase kinase 1 [K97R] Q02750

Human

IC50: 101

Dual specificity mitogen-activated protein kinase kinase 1/2 P36507 Q02750

Human

IC50: 124

Dual specificity mitogen-activated protein kinase kinase 1/2 P36506 Q01986

Rat

IC50: 1

Dual specificity mitogen-activated protein kinase kinase 1/Mitogen-activated protein kinase 1/Serine/threonine-protein kinase B-raf P15056 P28482 Q02750

Human

IC50: 101

Dual specificity mitogen-activated protein kinase kinase 1/RAF proto-oncogene serine/threonine-protein kinase P04049 Q02750

Human

IC50: 26

DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 P36506 P36507 Q01986 Q02750

Ki: 14 IC50: 180 Kd: 140

Dual specificity mitogen-activated protein kinase kinase 1/2 P36507 Q02750

Human

IC50: 124

Dual specificity mitogen-activated protein kinase kinase 1/2 P36506 Q01986

Rat

IC50: 1

Dual specificity mitogen-activated protein kinase kinase 2 P36507

Human

Ki: 14 IC50: 42 Kd: 140

Dual specificity mitogen-activated protein kinase kinase 2 P36506

Rat

IC50: 13

DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 3 P01106 P46734

Human

IC50: 50 Kd: 139 Koff: 1

Dual specificity mitogen-activated protein kinase kinase 3 P46734

Human

IC50: 17 Kd: 123 Koff: 1

Myc proto-oncogene protein P46734

Human

Kd: 1

Myc proto-oncogene protein P01106

Human

IC50: 33 Kd: 15

DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 P45985 P47809

IC50: 133 Kd: 132

Dual specificity mitogen-activated protein kinase kinase 4 P45985

Human

IC50: 133 Kd: 128

Dual specificity mitogen-activated protein kinase kinase 4 P47809

Mouse

Kd: 4

Dual specificity mitogen-activated protein kinase kinase 5 Q13163

Human

IC50: 18 Kd: 92

Dual specificity mitogen-activated protein kinase kinase 6 P52564

Human

Ki: 3 IC50: 39 Kd: 127

Dual specificity mitogen-activated protein kinase kinase 7 O14733

Human

Ki: 2 IC50: 77 Kd: 89 EC50: 10

DUAL SPECIFICITY PROTEIN KINASE CLK1 P22518 P49759 P49760 Q9HAZ1

Ki: 5 IC50: 1308 Kd: 203 EC50: 41

Dual specificity protein kinase CLK1 P49759

Human

Ki: 5 IC50: 1025 Kd: 187 EC50: 41

Dual specificity protein kinase CLK1 P22518

Mouse

IC50: 274

Dual specificity protein kinase CLK1 [R432A] P49759

Human

Kd: 16

Dual specificity protein kinase CLK1/CLK2 P49759 P49760

Human

IC50: 1

Dual specificity protein kinase CLK1/CLK4 P49759 Q9HAZ1

Human

IC50: 8

DUAL SPECIFICITY PROTEIN KINASE CLK2 O35491 P49759 P49760 P54619 Q13535 Q8WXE1 Q92547 Q9Y478

Ki: 33 IC50: 939 Kd: 165

5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2 P49760 P54619 Q9Y478

Human

IC50: 6

ATR-interacting protein/DNA topoisomerase 2-binding protein 1/Dual specificity protein kinase CLK2/Serine/threonine-protein kinase ATR P49760 Q13535 Q8WXE1 Q92547

Human

Ki: 32

Dual specificity protein kinase CLK1/CLK2 P49759 P49760

Human

IC50: 1

Dual specificity protein kinase CLK2 P49760

Human

Ki: 1 IC50: 789 Kd: 165

Dual specificity protein kinase CLK2 O35491

Mouse

IC50: 143

DUAL SPECIFICITY PROTEIN KINASE CLK3 O35492 P49761

Ki: 4 IC50: 644 Kd: 133

Dual specificity protein kinase CLK3 P49761

Human

Ki: 4 IC50: 216 Kd: 133

Dual specificity protein kinase CLK3 P49761

Human

IC50: 254

Dual specificity protein kinase CLK3 O35492

Mouse

IC50: 174

DUAL SPECIFICITY PROTEIN KINASE CLK4 O35493 P49759 Q9HAZ1

Ki: 2 IC50: 803 Kd: 155

Dual specificity protein kinase CLK1/CLK4 P49759 Q9HAZ1

Human

IC50: 8

Dual specificity protein kinase CLK4 Q9HAZ1

Human

Ki: 2 IC50: 645 Kd: 155

Dual specificity protein kinase CLK4 O35493

Mouse

IC50: 150

DUAL SPECIFICITY PROTEIN KINASE TTK P09211 P33981

Human

Ki: 58 IC50: 2225 Kd: 174 EC50: 3

Dual specificity protein kinase TTK P33981

Human

Ki: 58 IC50: 2196 Kd: 174 EC50: 3

Dual specificity protein kinase TTK [2-857] P33981

Human

IC50: 4

Dual specificity protein kinase TTK/Glutathione S-transferase P P09211 P33981

Human

IC50: 25

DUAL SPECIFICITY PROTEIN PHOSPHATASE 1 P28562 P28563

IC50: 433

Dual specificity protein phosphatase 1 P28562

Human

IC50: 418

Dual specificity protein phosphatase 1 P28563

Mouse

IC50: 15

Dual specificity protein phosphatase 10 Q9Y6W6

Human

Ki: 4 IC50: 28

Dual specificity protein phosphatase 14 O95147

Human

IC50: 1

Dual specificity protein phosphatase 15 Q9H1R2

Human

IC50: 2

Dual specificity protein phosphatase 2 Q05923

Human

IC50: 1

Dual specificity protein phosphatase 22 Q9NRW4

Human

Ki: 1 IC50: 64

Dual specificity protein phosphatase 23 Q9BVJ7

Human

IC50: 17

Dual specificity protein phosphatase 26 Q9BV47

Human

IC50: 14

Dual specificity protein phosphatase 3 P51452

Human

Ki: 32 IC50: 901

Dual specificity protein phosphatase 4 Q13115

Human

IC50: 7

DUAL SPECIFICITY PROTEIN PHOSPHATASE 5 Q16690

Human

Ki: 1 IC50: 24

Dual specificity protein phosphatase 5 Q16690

Human

IC50: 19

Dual specificity protein phosphatase 5 [180-384] Q16690

Human

Ki: 1 IC50: 5

DUAL SPECIFICITY PROTEIN PHOSPHATASE 6 Q16828 Q64346

IC50: 524

Dual specificity protein phosphatase 6 Q64346

Rat

IC50: 476

Dual specificity protein phosphatase 6 Q16828

Human

IC50: 48

Dual specificity protein phosphatase CDC14A Q9UNH5

Human

Ki: 1 IC50: 29

Dual specificity testis-specific protein kinase 1 Q15569

Human

IC50: 27 Kd: 124

Dual specificity testis-specific protein kinase 2 Q96S53

Human

IC50: 23

DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A Q13627 Q61214 Q63470

Ki: 66 IC50: 2918 Kd: 259 EC50: 4437 Koff: 10

Dual specificity tyrosine-phosphorylation-regulated kinase 1A Q13627

Human

Ki: 58 IC50: 2392 Kd: 259 EC50: 4437 Koff: 10

Dual specificity tyrosine-phosphorylation-regulated kinase 1A Q63470

Rat

Ki: 8 IC50: 511

Dual specificity tyrosine-phosphorylation-regulated kinase 1A Q61214

Mouse

IC50: 15

Dual specificity tyrosine-phosphorylation-regulated kinase 1B Q9Y463

Human

Ki: 21 IC50: 1026 Kd: 141

DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 2 Q92630

Human

Ki: 3 IC50: 772 Kd: 84

Dual specificity tyrosine-phosphorylation-regulated kinase 2 Q92630

Human

Ki: 3 IC50: 771 Kd: 84

Dual specificity tyrosine-phosphorylation-regulated kinase 2 [393-601] Q92630

Human

IC50: 1

Dual specificity tyrosine-phosphorylation-regulated kinase 3 O43781

Human

Ki: 1 IC50: 471

Dual specificity tyrosine-phosphorylation-regulated kinase 4 Q9NR20

Human

IC50: 316

DUF3553 DOMAIN-CONTAINING PROTEIN A0A1I7V8J2 A0A7S7LIM2 F6Z813 G5EB00

Ki: 10 IC50: 103

Uncharacterized protein A0A7S7LIM2

Cryptosporidium parvum

IC50: 103

Uncharacterized protein F6Z813

Chicken

Ki: 8

Uncharacterized protein A0A1I7V8J2

Eye worm

Ki: 1

Uncharacterized protein G5EB00

Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL194 / M139) (Aspergillus nidulans)

Ki: 1

DYNAMIN-1 P21575 Q05193

IC50: 185

Dynamin-1 Q05193

Human

IC50: 179

Dynamin-1 P21575

Rat

IC50: 6

Dynamin-1-like protein O00429

Human

IC50: 71

DYNAMIN-2 P39052 P50570

IC50: 44

Dynamin-2 P50570

Human

IC50: 38

Dynamin-2 P39052

Rat

IC50: 6

Dynein light chain 2, cytoplasmic Q96FJ2

Human

IC50: 6

Dystrophin P11532

Human

IC50: 355

Curated by BindingDB

Curated by ChEMBL