Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with Target = 'DNA polymerase subunit gamma-1'
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408427BDBM50408427(CHEMBL483492)
Affinity DataIC50: 500nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21687BDBM21687(deoxyguanosine triphosphate | ({[({[(2R,3S,5R)-5-(...)
Affinity DataKd:  800nMAssay Description:Binding affinity to exonuclase deficient human recombinant DNA polymerase gamma E200A mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808523BDBM808523((R)-4-chloro-2,5-dimethyl-N-(3-(2- methylpyrrolidi...)
Affinity DataIC50: 800nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248359BDBM50248359(Adefovir dipivoxil | GS-0840 | Hepsera)
Affinity DataKi:  970nMAssay Description:Binding affinity to human DNA polymerase gamma assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808520BDBM808520(N-(3-(3-cyanomorpholine-4- carbonyl)phenyl)-2,5- d...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480766BDBM50480766(CHEBI:16311 | 2''-Deoxycytidine 5''-Triphosphate |...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to human DNA polymerase gamma assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408426BDBM50408426(CHEMBL2092833)
Affinity DataIC50: 1.50E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408426BDBM50408426(CHEMBL2092833)
Affinity DataIC50: 1.50E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808522BDBM808522((R)-4-chloro-2,5-dimethyl-N-(3-(2- methylpiperidin...)
Affinity DataIC50: 2.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408425BDBM50408425(CHEMBL2092835)
Affinity DataIC50: 2.00E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50448482BDBM50448482(CHEMBL3126408)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of DNA polymerase-gamma (unknown origin) assessed as incorporation of Br(d)UTP by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808527BDBM808527(3-((4-chloro-2,5- dimethylphenyl)sulfonamido)-N-(1...)
Affinity DataIC50: 3.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808518BDBM808518((R)-2,5-dimethyl-N-(3-(2- methylpiperidine-1- carb...)
Affinity DataIC50: 3.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808515BDBM808515(N-(3-(2-cyanopiperidine-1- carbonyl)phenyl)-2,5- d...)
Affinity DataIC50: 4.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808525BDBM808525(3-((4-chloro-2,5- dimethylphenyl)sulfonamido)-N,N-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808526BDBM808526((R)-4-chloro-N-(3-fluoro-5-(2- methylpyrrolidine-1...)
Affinity DataIC50: 6.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50478747BDBM50478747(Acyclovir triphosphate)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity to exonuclase deficient human recombinant DNA polymerase gamma E200A mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808532BDBM808532(4-chloro-2,5-dimethyl-N-(2-oxoindolin- 5-yl)benzen...)
Affinity DataIC50: 6.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808514BDBM808514((R)-4-chloro-2,5-dimethyl-N-(3-(3- methylmorpholin...)
Affinity DataIC50: 7.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808533BDBM808533(4-chloro-N-(3-(4-cyclopropyl-1-methyl- 1H-imidazol...)
Affinity DataIC50: 7.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808531BDBM808531(4-chloro-2,5-dimethyl-N-(3-(1-methyl- 1H-imidazol-...)
Affinity DataIC50: 8.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808521BDBM808521((S)-N-(1-cyclopropylethyl)-3-((2,5- dimethylphenyl...)
Affinity DataIC50: 9.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191511BDBM50191511(2-{4-[4'-chloro-4-(2-oxopyrrolidin-1-yl)biphenyl-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DNA polymerase gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808516BDBM808516(2-methyl-N-(3-(piperidine-1- carbonyl)phenyl)benze...)
Affinity DataIC50: 1.00E+4nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428818BDBM50428818(CHEMBL3142662)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of rat DNA polymerase beta using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808528BDBM808528(4-chloro-2,5-dimethyl-N-(3-(thiazol-2- yl)phenyl)b...)
Affinity DataIC50: 1.20E+4nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808519BDBM808519((S)-2,5-dimethyl-N-(3-(2- methylpiperidine-1- carb...)
Affinity DataIC50: 1.20E+4nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138406BDBM50138406([(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-o...)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to human DNA polymerase gamma assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251277BDBM50251277(Kasanosin A | CHEMBL458178)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human DNA polymerase gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808517BDBM808517(N-(cyclopropylmethyl)-3-((2,5- dimethylphenyl)sulf...)
Affinity DataIC50: 4.80E+4nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408425BDBM50408425(CHEMBL2092835)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408427BDBM50408427(CHEMBL483492)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335554BDBM50335554(({[({[2-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)e...)
Affinity DataIC50: 5.94E+4nMAssay Description:Inhibition of human DNA polymerase gamma by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138405BDBM50138405([(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-...)
Affinity DataKd:  6.30E+4nMAssay Description:Binding affinity to human DNA polymerase gamma assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251278BDBM50251278(Kasanosin B | CHEMBL457091)
Affinity DataIC50: 7.29E+4nMAssay Description:Inhibition of human DNA polymerase gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205415BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
Affinity DataIC50: 8.00E+4nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808530BDBM808530(4-chloro-2,5-dimethyl-N-(3-(1-methyl- 1H-pyrazol-3...)
Affinity DataIC50: 8.10E+4nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333127BDBM50333127((beta-D-2',3'-dideoxy-5'-F-cytidine-5'-triphosphat...)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of human DNA polymerase gamma assessed as incorporation of [alpha-32P]dCTP up to 1mM preincubated for 30 mins by whatman DE81 paper bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808524BDBM808524(N-benzyl-3-((4-chloro-2,5- dimethylphenyl)sulfonam...)
Affinity DataIC50: 1.00E+5nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408428BDBM50408428(CHEMBL2092834)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336502BDBM50336502(10-acetyl-11-(2,4-dichlorophenyl)-3,3-dimethyl-2,3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DNA polymerase gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336503BDBM50336503(10-acetyl-11-(3-(benzyloxy)-4-methoxyphenyl)-3,3-d...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DNA polymerase gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591035BDBM50591035(CHEMBL5187422)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DNA polymerase gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808529BDBM808529(4-chloro-2,5-dimethyl-N-(3-(oxazol-2- yl)phenyl)be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408428BDBM50408428(CHEMBL2092834)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021053BDBM50021053(CHEMBL3287609)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DNA polymerase gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090910BDBM50090910(6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DNA polymerase gamma assessed as incorporation of [alpha-32P]dCTP up to 1mM preincubated for 30 mins by whatman DE81 paper bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335556BDBM50335556([({[({2-[2-amino-6-(cyclopropylamino)-9H-purin-9-y...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human DNA polymerase gamma by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428818BDBM50428818(CHEMBL3142662)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human DNA polymerase kappa using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Max Delbruck Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428818BDBM50428818(CHEMBL3142662)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human DNA polymerase mu using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
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