Compile Data Set for Download or QSAR
Report error Found 560 Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 84'
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189503(CHEMBL3828298)
Affinity DataEC50:  0.189nMAssay Description:Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189503(CHEMBL3828298)
Affinity DataEC50:  0.189nMAssay Description:Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataKi:  0.219nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50548387(CHEMBL4794652)
Affinity DataKd:  0.240nMAssay Description:Binding affinity to recombinant human N-terminal epitope tagged/eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cell membrane incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511034(CHEMBL4444010)
Affinity DataKi:  0.317nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189527(CHEMBL3827310)
Affinity DataKi:  0.324nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50089889(6-(4-Phenyl-butylamino)-1H-pyrimidine-2,4-dione | ...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511014(CHEMBL4547165)
Affinity DataKi:  0.582nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50548398(CHEMBL3718309)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at recombinant human GPR84 stably overexpressed in HEK293T cell membranes co-expressing G-alpha assessed as inhibition of DIM-sti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189502(CHEMBL3827832)
Affinity DataKi:  0.626nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511013(CHEMBL4538049)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189515(CHEMBL3828415)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511011(CHEMBL125436)
Affinity DataKi:  0.726nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  0.790nMAssay Description:Agonist activity at recombinant human N-terminal epitope tagged/C-terminal eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cell membranes a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511042(CHEMBL4468895)
Affinity DataKi:  0.866nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at human Flag-tagged Gialpha-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as reduction in PSB-16671-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  1nMAssay Description:Agonist activity at recombinant human N-terminal epitope tagged/C-terminal eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cell membranes a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511010(CHEMBL4521587)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511044(CHEMBL4580884)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189504(CHEMBL3827638)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189505(CHEMBL13302)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511001(CHEMBL4439640)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50078852(CHEMBL221598)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human GPR84 expressed in HEK293 cells assessed as reduction in forskolin-stimulated cAMP production incubated for 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189503(CHEMBL3828298)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511046(CHEMBL4528940)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50510998(CHEMBL4571353)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511034(CHEMBL4444010)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cells co-expressing beta-galactosidase/beta-arrestin2 assessed as inhibition of forskoli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511025(CHEMBL4438595)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50028344(6-Hexylamino-1H-pyrimidine-2,4-dione | CHEMBL12497...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511019(CHEMBL4528577)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50028344(6-Hexylamino-1H-pyrimidine-2,4-dione | CHEMBL12497...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cells assessed as beta-arrestin 2 recruitment measured after 90 mins by beta-galactosida...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511049(CHEMBL4562761)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511026(CHEMBL4534827)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511020(CHEMBL4568775)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511003(CHEMBL4467630)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511053(CHEMBL4468678)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50603899(CHEMBL5205352)
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in 6-OAU induced intracellular calcium resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50599123(CHEMBL5170226)
Affinity DataIC50: 4.70nMAssay Description:Antagonist activity at human Galphai2-fused GPR84 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of PSB-16671-induced [35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at GPR84 in LPS-treated human THP-1 cell membrane assessed as reduction in PSB-16671-induced stimulation of [35S]GTPgammaS bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511016(CHEMBL4473999)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50028344(6-Hexylamino-1H-pyrimidine-2,4-dione | CHEMBL12497...)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cells co-expressing beta-galactosidase/beta-arrestin2 assessed as inhibition of forskoli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50548387(CHEMBL4794652)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at recombinant human GPR84 stably overexpressed in HEK293T cell membranes co-expressing G-alpha assessed as inhibition of DIM-sti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50599096(CHEMBL5186088)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human Galphai2-fused GPR84 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of PSB-16671-induced [35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50599101(CHEMBL5180818)
Affinity DataIC50: 5.20nMAssay Description:Antagonist activity at human Galphai2-fused GPR84 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of PSB-16671-induced [35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50548393(CHEMBL3716446)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at recombinant human GPR84 receptor expressed in HEK293 cells co-expressing GNAO1 transcription variant 1 assessed as reduction i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50189507(CHEMBL3828303)
Affinity DataEC50:  6.10nMAssay Description:Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50603880(CHEMBL5191944)
Affinity DataIC50: 6.70nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in 6-OAU induced intracellular calcium resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50511035(CHEMBL4451909)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50599063(CHEMBL5171669)
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity at human Galphai2-fused GPR84 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of PSB-16671-induced [35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity at human Flag-tagged Gialpha-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as reduction in ZQ-16-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
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