Compile Data Set for Download or QSAR
Report error Found 181 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2'
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648759(CHEMBL5612684)
Affinity DataKd:  7.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648760(CHEMBL5614248)
Affinity DataKd:  4.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648761(CHEMBL5613485)
Affinity DataKd:  5.10E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648762(CHEMBL5614154)
Affinity DataKd:  4.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648763(CHEMBL5613338)
Affinity DataKd:  3.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648764(CHEMBL5612969)
Affinity DataKd:  3.60E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648765(CHEMBL5611897)
Affinity DataKd:  5.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648766(CHEMBL5613882)
Affinity DataKd:  4.70E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648759(CHEMBL5612684)
Affinity DataKd:  6.10E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648760(CHEMBL5614248)
Affinity DataKd:  4.70E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648761(CHEMBL5613485)
Affinity DataKd:  4.10E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648762(CHEMBL5614154)
Affinity DataKd:  1.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648763(CHEMBL5613338)
Affinity DataKd:  2.90E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648764(CHEMBL5612969)
Affinity DataKd:  2.40E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648765(CHEMBL5611897)
Affinity DataKd:  4.40E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648766(CHEMBL5613882)
Affinity DataKd:  3.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648767(CHEMBL5613061)
Affinity DataKd:  3.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648760(CHEMBL5614248)
Affinity DataKd:  1.40E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648765(CHEMBL5611897)
Affinity DataKd:  1.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648766(CHEMBL5613882)
Affinity DataKd:  2.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50648768(CHEMBL5613508)
Affinity DataKd:  1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  488nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  176nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50586355(CHEMBL5087243)
Affinity DataIC50: 23nMAssay Description:Inhibition of 2-FAM-InsP5 binding to human SHIP2 catalytic domain (419 to 832 residues) assessed as change in polarization by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50586354(CHEMBL5078323)
Affinity DataIC50: 27nMAssay Description:Inhibition of 2-FAM-InsP5 binding to human SHIP2 catalytic domain (419 to 832 residues) assessed as change in polarization by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50586353(CHEMBL5092991)
Affinity DataIC50: 29nMAssay Description:Inhibition of 2-FAM-InsP5 binding to human SHIP2 catalytic domain (419 to 832 residues) assessed as change in polarization by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50586357(CHEMBL5080660)
Affinity DataIC50: 31nMAssay Description:Inhibition of 2-FAM-InsP5 binding to human SHIP2 catalytic domain (419 to 832 residues) assessed as change in polarization by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50586356(CHEMBL5081948)
Affinity DataIC50: 61nMAssay Description:Inhibition of 2-FAM-InsP5 binding to human SHIP2 catalytic domain (419 to 832 residues) assessed as change in polarization by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 200nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 200nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 200nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 200nMAssay Description:PTP assays were conducted as previously described in Kontaridis et al., J Biol Chem. 2006; 281:6785-6792, using para-nitrophenyl phosphate (pNPP, obt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 200nMAssay Description:PTP assays were conducted as previously described in Kontaridis et al., J Biol Chem. 2006; 281:6785-6792, using para-nitrophenyl phosphate (pNPP, obt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054257(US9522881, 11a-21 L97L08 | CHEMBL3319376 | US98445...)
Affinity DataIC50: 220nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054257(US9522881, 11a-21 L97L08 | CHEMBL3319376 | US98445...)
Affinity DataIC50: 220nMAssay Description:PTP assays were conducted as previously described in Kontaridis et al., J Biol Chem. 2006; 281:6785-6792, using para-nitrophenyl phosphate (pNPP, obt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054258(US9522881, 11a-22 L97L07 | CHEMBL3319377 | US98445...)
Affinity DataIC50: 310nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054258(US9522881, 11a-22 L97L07 | CHEMBL3319377 | US98445...)
Affinity DataIC50: 310nMAssay Description:PTP assays were conducted as previously described in Kontaridis et al., J Biol Chem. 2006; 281:6785-6792, using para-nitrophenyl phosphate (pNPP, obt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054259(US9522881, 11a-23 L97L03 | CHEMBL3319378)
Affinity DataIC50: 370nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM362880(US9844535, ID 11a-23 L97L03)
Affinity DataIC50: 370nMAssay Description:PTP assays were conducted as previously described in Kontaridis et al., J Biol Chem. 2006; 281:6785-6792, using para-nitrophenyl phosphate (pNPP, obt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054260(US9522881, 11a-24 L97L05 | CHEMBL3319379 | US98445...)
Affinity DataIC50: 380nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054260(US9522881, 11a-24 L97L05 | CHEMBL3319379 | US98445...)
Affinity DataIC50: 380nMAssay Description:PTP assays were conducted as previously described in Kontaridis et al., J Biol Chem. 2006; 281:6785-6792, using para-nitrophenyl phosphate (pNPP, obt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Mouse)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50511342(CHEMBL4538474)
Affinity DataIC50: 390nMAssay Description:Inhibition of SHIP2 in serum-starved mouse Mm1 cells assessed as reduction in Akt phosphorylation incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054261(US9522881, 11a-25 L97L06 | CHEMBL3319380 | US98445...)
Affinity DataIC50: 420nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054261(US9522881, 11a-25 L97L06 | CHEMBL3319380 | US98445...)
Affinity DataIC50: 420nMAssay Description:PTP assays were conducted as previously described in Kontaridis et al., J Biol Chem. 2006; 281:6785-6792, using para-nitrophenyl phosphate (pNPP, obt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054406(US9522881, 11a-2 (L97N08) | CHEMBL3319357 | US9844...)
Affinity DataIC50: 620nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50430584(CHEMBL2337806)
Affinity DataIC50: 620nMAssay Description:Inhibition of SHIP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054406(US9522881, 11a-2 (L97N08) | CHEMBL3319357 | US9844...)
Affinity DataIC50: 620nMAssay Description:PTP assays were conducted as previously described in Kontaridis et al., J Biol Chem. 2006; 281:6785-6792, using para-nitrophenyl phosphate (pNPP, obt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054262(US9522881, 11a-26 L97L02 | CHEMBL3319381 | US98445...)
Affinity DataIC50: 630nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054262(US9522881, 11a-26 L97L02 | CHEMBL3319381 | US98445...)
Affinity DataIC50: 630nMAssay Description:PTP assays were conducted as previously described in Kontaridis et al., J Biol Chem. 2006; 281:6785-6792, using para-nitrophenyl phosphate (pNPP, obt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
Institute of Biostructures and Bioimaging

Curated by ChEMBL
LigandPNGBDBM50054405(US9522881, 11a-3 (L97M50) | CHEMBL3319358 | US9844...)
Affinity DataIC50: 660nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

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